(Q47679613)

4 February 2018

title

MyD88 is required for mounting a robust host immune response to Streptococcus pneumoniae in the CNS. (English)

1 reference

4 February 2018

main subject

Streptococcus pneumoniae

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7

Carsten J Kirschning

1 reference

4 February 2018

Hermann Wagner

5

object named as

Hermann Wagner

1 reference

4 February 2018

Barbara Angele

3

object named as

Barbara Angele

1 reference

4 February 2018

author name string

Uwe Koedel

1

1 reference

4 February 2018

Tobias Rupprecht

2

1 reference

4 February 2018

Juergen Heesemann

4

1 reference

4 February 2018

Hans-Walter Pfister

6

1 reference

4 February 2018

language of work or name

English

0 references

publication date

28 April 2004

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4 February 2018

published in

Brain

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4 February 2018

volume

127

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4 February 2018

page(s)

1437-1445

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4 February 2018

issue

Pt 6

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4 February 2018

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

cites work

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Toll-like receptor 2-deficient mice are highly susceptible to Streptococcus pneumoniae meningitis because of reduced bacterial clearing and enhanced inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

A universal role for MyD88 in TLR/IL-1R-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Pneumococcal meningitis in adults: Spectrum of complications and prognostic factors in a series of 87 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Pathogenesis of bacterial meningitis: from bacteraemia to neuronal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Pathogenesis and pathophysiology of pneumococcal meningitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Role of Caspase-1 in experimental pneumococcal meningitis: Evidence from pharmacologic Caspase inhibition and Caspase-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Toll-like receptor 2 participates in mediation of immune response in experimental pneumococcal meningitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Circulating cell wall components derived from gram-negative, not gram-positive, bacteria cause a profound induction of the gene-encoding Toll-like receptor 2 in the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Current concepts in the pathogenesis of meningitis caused by Streptococcus pneumoniae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

The role of MyD88-like adapters in Toll-like receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

The pneumococcus: carriage, disease and conjugate vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

The burden of invasive pneumococcal disease and the potential for reduction by immunisation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Lack of IL-6 augments inflammatory response but decreases vascular permeability in bacterial meningitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

The Induction of Meningeal Inflammation by Components of the Pneumococcal Cell Wall

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

The role of complement in inflammation during experimental pneumococcal meningitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Decreased virulence of a pneumolysin-deficient strain of Streptococcus pneumoniae in murine meningitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

IL-1 Receptor Type 1 Gene-Deficient Mice Demonstrate an Impaired Host Defense Against Pneumococcal Meningitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Interleukin-18 gene-deficient mice show enhanced defense and reduced inflammation during pneumococcal meningitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

Ventricular involvement in experimental Hemophilus influenzae meningitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWH171

21 January 2018

Identifiers

DOI

10.1093/BRAIN/AWH171

1 reference

4 February 2018

PubMed ID

15115715

1 reference

4 February 2018