(Q47681955)

4 February 2018

title

Antibodies expose multiple weaknesses in the glycan shield of HIV. (English)

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4 February 2018

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1

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4 February 2018

Thomas A. Bowden

object named as

Thomas A Bowden

series ordinal

2

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publication date

1 July 2013

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4 February 2018

Nature Structural & Molecular Biology

published in

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4 February 2018

volume

20

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4 February 2018

issue

7

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4 February 2018

page(s)

771-772

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4 February 2018

N-linked glycosylation of the V3 loop and the immunologically silent face of gp120 protects human immunodeficiency virus type 1 SF162 from neutralization by anti-gp120 and anti-gp41 antibodies

cites work

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The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.

21 January 2018

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Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens.

21 January 2018

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Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

21 January 2018

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Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

21 January 2018

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The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.

21 January 2018

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The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.

21 January 2018

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Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

21 January 2018

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A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals

21 January 2018

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A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

21 January 2018

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Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

21 January 2018

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Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies

21 January 2018

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Antibody neutralization and escape by HIV-1

21 January 2018

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Variable loop glycan dependency of the broad and potent HIV-1-neutralizing antibodies PG9 and PG16.

21 January 2018

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Exploiting the defensive sugars of HIV-1 for drug and vaccine design

21 January 2018

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Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.

21 January 2018

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Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans

21 January 2018

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Yeast-elicited cross-reactive antibodies to HIV Env glycans efficiently neutralize virions expressing exclusively high-mannose N-linked glycans

21 January 2018

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Antibodies against Manalpha1,2-Manalpha1,2-Man oligosaccharide structures recognize envelope glycoproteins from HIV-1 and SIV strains

21 January 2018

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Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/NSMB.2627

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4 February 2018

release_xd24vc2h2nfirki6si4q2yxaxm

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/xd24vc2h2nfirki6si4q2yxaxm

mapped directly with Wikidata item

24 November 2022

based on heuristic

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4 February 2018