(Q47685656)

4 February 2018

title

Identification and functional characterization of diterpene synthases for triptolide biosynthesis from Tripterygium wilfordii (English)

1 reference

4 February 2018

Sandaracopimara-8(14),15-diene

main subject

Tripterygium wilfordii

2 references

1 reference

inferred from

reverse claim

(2R,4aS,6aS,12bR,14aS,14bR)-9-formyl-10,11-dihydroxy-2,4a,6a,12b,14a-pentamethyl-8-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid

1 reference

1 reference

1 reference

ent-Kauran-16-beta-ol

1 reference

inferred from

reverse claim

[(1S,3S,15R,18R,19S,20S,21S,22S,23S,24R,25S,26S)-20,22,23,25-tetraacetyloxy-19,26-dihydroxy-3,15,26-trimethyl-6,16-dioxo-2,5,17-trioxa-11-azapentacyclo[16.7.1.01,21.03,24.07,12]hexacosa-7(12),8,10-trien-21-yl]methyl acetate

1 reference

inferred from

reverse claim

8-methoxy-1,1,4a-trimethyl-7-propan-2-yl-4,9,10,10a-tetrahydro-3H-phenanthren-2-one

1 reference

1 reference

(1S,2S,4S,5S,7S,9S,11S,13S)-7-isopropyl-1-methyl-3,6,10,16-tetraoxaheptacyclo[11.7.0.0²,⁴.0²,⁹.0⁵,⁷.0⁹,¹¹.0¹⁴,¹⁸]icos-14(18)-ene-8,17-dione

1 reference

1 reference

9-(Furan-3-carbonyl)-2-phenyl-1,5,9-triazacyclotridecan-4-one

1 reference

13

1 reference

4 February 2018

author name string

Ping Su

1

1 reference

4 February 2018

Hongyu Guan

2

1 reference

4 February 2018

Yujun Zhao

3

1 reference

4 February 2018

Yuru Tong

4

1 reference

4 February 2018

Meimei Xu

5

1 reference

4 February 2018

Yifeng Zhang

6

1 reference

4 February 2018

Tianyuan Hu

7

1 reference

4 February 2018

Jian Yang

8

1 reference

4 February 2018

Qiqing Cheng

9

1 reference

4 February 2018

Linhui Gao

10

1 reference

4 February 2018

Yujia Liu

11

1 reference

4 February 2018

Jiawei Zhou

12

1 reference

4 February 2018

Luqi Huang

14

1 reference

4 February 2018

Wei Gao

15

1 reference

4 February 2018

publication date

31 October 2017

1 reference

4 February 2018

full work available at URL

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/tpj.13756

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1111/tpj.13756?email=unpaywall_01@example.com

published in

The Plant Journal

1 reference

4 February 2018

volume

93

1 reference

4 February 2018

issue

1

1 reference

4 February 2018

page(s)

50-65

1 reference

4 February 2018

https://api.unpaywall.org/v2/10.1111/tpj.13756?email=unpaywall_01@example.com

1 reference

19 March 2024

access restriction status

open access

1 reference

inferred from online access status

cites work

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1 reference

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29 September 2018

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Two residues determine the product profile of the class II diterpene synthases TPS14 and TPS21 of Tripterygium wilfordii.

29 September 2018

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29 September 2018

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29 September 2018

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The terpene synthase gene family in Tripterygium wilfordii harbors a labdane-type diterpene synthase among the monoterpene synthase TPS-b subfamily.

29 September 2018

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29 September 2018

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One amino acid makes the difference: the formation of ent-kaurene and 16α-hydroxy-ent-kaurane by diterpene synthases in poplar

29 September 2018

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Identification of geranylgeranyl diphosphate synthase genes from Tripterygium wilfordii

29 September 2018

1 reference

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Transcriptional Mechanism of Jasmonate Receptor COI1-Mediated Delay of Flowering Time in Arabidopsis

29 September 2018

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29 September 2018

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Characterization of eight terpenoids from tissue cultures of the Chinese herbal plant, Tripterygium wilfordii, by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry

29 September 2018

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29 September 2018

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29 September 2018

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29 September 2018

1 reference

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Characterization of CYP76AH4 clarifies phenolic diterpenoid biosynthesis in the Lamiaceae

29 September 2018

1 reference

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Triptolide with potential medicinal value for diseases of the central nervous system

29 September 2018

1 reference

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29 September 2018

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Natural product triptolide mediates cancer cell death by triggering CDK7-dependent degradation of RNA polymerase II.

29 September 2018

1 reference

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Terpenoid synthase structures: a so far incomplete view of complex catalysis

29 September 2018

1 reference

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Effects of triptolide on the synaptophysin expression of hippocampal neurons in the AD cellular model

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5848467

Full-length transcriptome assembly from RNA-Seq data without a reference genome

29 September 2018

1 reference

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The family of terpene synthases in plants: a mid-size family of genes for specialized metabolism that is highly diversified throughout the kingdom

29 September 2018

1 reference

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XPB, a subunit of TFIIH, is a target of the natural product triptolide.

29 September 2018

1 reference

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Two rings in them all: the labdane-related diterpenoids

29 September 2018

1 reference

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Triptolide reduces cyst formation in a neonatal to adult transition Pkd1 model of ADPKD

29 September 2018

1 reference

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Identification and functional characterization of monofunctional ent-copalyl diphosphate and ent-kaurene synthases in white spruce reveal different patterns for diterpene synthase evolution for primary and secondary metabolism in gymnosperms

29 September 2018

1 reference

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A functional genomics approach to tanshinone biosynthesis provides stereochemical insights.

29 September 2018

1 reference

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Triptolide exerts anti-tumor effect on oral cancer and KB cells in vitro and in vivo

29 September 2018

1 reference

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29 September 2018

1 reference

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Triptolide inhibits COX-2 expression and PGE2 release by suppressing the activity of NF-kappaB and JNK in LPS-treated microglia

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5848467

Triptolide protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats: implication for immunosuppressive therapy in Parkinson's disease

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5848467

A modular approach for facile biosynthesis of labdane-related diterpenes

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5848467

Identification and functional analysis of bifunctional ent-kaurene synthase from the moss Physcomitrella patens.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5848467

Triptolide, a Chinese herbal extract, protects dopaminergic neurons from inflammation-mediated damage through inhibition of microglial activation

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5848467

Neurotrophic and neuroprotective effects of tripchlorolide, an extract of Chinese herb Tripterygium wilfordii Hook F, on dopaminergic neurons

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5848467

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5848467

The Chinese anti-inflammatory and immunosuppressive herbal remedy Tripterygium wilfordii Hook F.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5848467

The GA2 locus of Arabidopsis thaliana encodes ent-kaurene synthase of gibberellin biosynthesis

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5848467

The CTAB-DNA precipitation method: a common mini-scale preparation of template DNA from phagemids, phages or plasmids suitable for sequencing

29 September 2018

1 reference

12 December 2020

Identification of the single amino acid involved in quenching the ent-kauranyl cation by a water molecule in ent-kaurene synthase of Physcomitrella patens

1 reference

12 December 2020

Mutational analysis of white spruce (Picea glauca) ent-kaurene synthase (PgKS) reveals common and distinct mechanisms of conifer diterpene synthases of general and specialized metabolism

1 reference

12 December 2020

Tumor inhibitors. LXXIV. Triptolide and tripdiolide, novel antileukemic diterpenoid triepoxides from Tripterygium wilfordii

1 reference

12 December 2020

[Difficulties and countermeasures in treatment of rheumatoid arthritis with Tripterygium]

1 reference

12 December 2020

[Construction of Saccharomyces cerevisiae cell factories for lycopene production]

1 reference

12 December 2020

Modular Pathway Engineering of Diterpenoid Synthases and the Mevalonic Acid Pathway for Miltiradiene Production

1 reference

12 December 2020

Studies with plant-cell cultures of the Chinese herbal plant, Tripterygium wilfordii. Isolation and characterization of diterpenes

1 reference

COCI

https://opencitations.net/index/api/v1/citations/10.1002/RECL.19961150115

Tripdiolide from Tissue Culture of Tripterygium wilfordii

10 April 2024

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.3987/R-1980-10-1465

Identifiers

DOI

10.1111/TPJ.13756

1 reference

4 February 2018

PMC publication ID

5848467

0 references

1 reference

4 February 2018