(Q47720716)

5 February 2018

review article

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title

Understanding fetal globin gene expression: a step towards effective HbF reactivation in haemoglobinopathies. (English)

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5 February 2018

author name string

Jane SM

series ordinal

1

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5 February 2018

Cunningham JM

series ordinal

2

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5 February 2018

language of work or name

English

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publication date

1 July 1998

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5 February 2018

British Journal of Haematology

published in

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5 February 2018

volume

102

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5 February 2018

issue

2

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5 February 2018

page(s)

415-422

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5 February 2018

Participation of the human beta-globin locus control region in initiation of DNA replication

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The activation domain of the enhancer binding protein p45NF-E2 interacts with TAFII130 and mediates long-range activation of the alpha- and beta-globin gene loci in an erythroid cell line

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21 January 2018

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Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia

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Proportion of fetal hemoglobin synthesis decreases during erythroid cell maturation

21 January 2018

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Dissecting the loci controlling fetal haemoglobin production on chromosomes 11p and 6q by the regressive approach.

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5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons

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Gamma delta beta-thalassemia due to a de novo mutation deleting the 5' beta-globin gene activation-region hypersensitive sites

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Developmental regulation of human fetal-to-adult globin gene switching in transgenic mice.

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A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus.

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DNaseI hypersensitive sites 1, 2 and 3 of the human beta-globin dominant control region direct position-independent expression

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Mechanism of Hb F stimulation by S-stage compounds. In vitro studies with bone marrow cells exposed to 5-azacytidine, Ara-C, or hydroxyurea

21 January 2018

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Position-independent, high-level expression of the human beta-globin gene in transgenic mice

21 January 2018

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Importance of globin gene order for correct developmental expression.

21 January 2018

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5-Azacytidine acts directly on both erythroid precursors and progenitors to increase production of fetal hemoglobin

21 January 2018

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Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins

21 January 2018

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Molecular mechanisms of hemoglobin switching

21 January 2018

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Methylation-enhanced binding of Sp1 to the stage selector element of the human gamma-globin gene promoter may regulate development specificity of expression

21 January 2018

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Increased gamma-globin expression in a nondeletion HPFH mediated by an erythroid-specific DNA-binding factor

21 January 2018

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A case of hereditary persistence of fetal hemoglobin caused by a gene not linked to the beta-globin cluster

21 January 2018

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A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins

21 January 2018

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Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner

21 January 2018

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Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2141.1998.00811.X

Regulation of globin gene expression in erythroid cells.

21 January 2018

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Transcription factors and hematopoietic development

21 January 2018

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Cellular regulation of hemoglobin switching: evidence for inverse relationship between fetal hemoglobin synthesis and degree of maturity of human erythroid cells

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2141.1998.00811.X

Silencing of human fetal globin expression is impaired in the absence of the adult beta-globin gene activator protein EKLF.

21 January 2018

1 reference

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Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF

21 January 2018

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Delay in the fetal globin switch in infants of diabetic mothers

21 January 2018

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Butyrate infusions in the ovine fetus delay the biologic clock for globin gene switching

21 January 2018

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Increased Sp1 binding mediates erythroid-specific overexpression of a mutated (HPFH) gamma-globulin promoter

21 January 2018

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Genetic treatment of the haemoglobinopathies: recombinations and new combinations

21 January 2018

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Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene

21 January 2018

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Stochastic expression of fetal hemoglobin in adult erythroid cells

21 January 2018

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Therapeutic approaches to hemoglobin switching in treatment of hemoglobinopathies

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2141.1998.00811.X

The "beta-like-globin" gene domain in human erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1998.00811.X

Fetal hemoglobin synthesis in vivo: direct evidence for control at the level of erythroid progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1998.00811.X

DNA methylation in the human γδβ-globin locus in erythroid and nonerythroid tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1998.00811.X

Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1998.00811.X

The role of EKLF in human beta-globin gene competition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1998.00811.X

Transcription complex stability and chromatin dynamics in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1998.00811.X

Human γ-globin genes silenced independently of other genes in the β-globin locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.1998.00811.X

10.1046/J.1365-2141.1998.00811.X

21 January 2018

Identifiers

DOI

1 reference

5 February 2018

PubMed ID

9695955

1 reference

5 February 2018