(Q47796604)

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The arthritogenic and immunostimulatory properties of phosphorothioate oligodeoxynucleotides rely on synergy between the activities of the nuclease-resistant backbone and CpG motifs.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15072229%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

The arthritogenic and immunostimulatory properties of phosphorothioate oligodeoxynucleotides rely on synergy between the activities of the nuclease-resistant backbone and CpG motifs (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15072229%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15072229%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Andrej Tarkowski

3

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Andrej Tarkowski

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15072229%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

author name string

Kristina Eriksson

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15072229%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

L Vincent Collins

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15072229%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

publication date

1 February 2004

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Europe PubMed Central

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26 December 2019

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15072229%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

28

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15072229%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15072229%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

39-51

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15072229%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

https://scigraph.springernature.com/pub.10.1023/b:ifla.0000014710.44475.94

0 references

IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro inhibition of murine IFN gamma production by phosphorothioate deoxyguanosine oligomers

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonspecific Suppression of [3H]Thymidine Incorporation by "Control" Oligonucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of a hexameric deoxyriboguanosine run conjugation into CpG oligodeoxynucleotides on their immunostimulatory potentials

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Toll-like receptor recognizes bacterial DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intra-articularly localized bacterial DNA containing CpG motifs induces arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorothioate backbone modification modulates macrophage activation by CpG DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor-alpha-mediated shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of human B cells by phosphorothioate oligodeoxynucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphodiester CpG oligonucleotides as adjuvants: polyguanosine runs enhance cellular uptake and improve immunostimulative activity of phosphodiester CpG oligonucleotides in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting Edge: Identification of c-Rel-Dependent and -Independent Pathways of IL-12 Production During Infectious and Inflammatory Stimuli

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The features of arthritis induced by CpG motifs in bacterial DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The major role of macrophages and their product tumor necrosis factor alpha in the induction of arthritis triggered by bacterial DNA containing CpG motifs

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of different chemically modified oligodeoxynucleotides on immune stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synovial cytokine mRNA expression during arthritis triggered by CpG motifs of bacterial DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of CpG motifs in innate immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 6 plays a key role in the development of antigen-induced arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorothioate oligodeoxynucleotides promote the in vitro development of human allergen-specific CD4+ T cells into Th1 effectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG ODN-mediated regulation of IL-12 p40 transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive and negative regulatory elements contribute to CpG oligonucleotide-mediated regulation of human IL-6 gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG DNA, a novel immune enhancer for systemic and mucosal immunization with influenza virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatogenic properties of bacterial DNA following cutaneous exposure

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG motifs in bacterial DNA trigger direct B-cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid induction of mitogen-activated protein kinases by immune stimulatory CpG DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG motifs in bacterial DNA cause inflammation in the lower respiratory tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor 9 mediates CpG-DNA signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG DNA rescues B cells from apoptosis by activating NFkappaB and preventing mitochondrial membrane potential disruption via a chloroquine-sensitive pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG oligodeoxynucleotides rescue BKS-2 immature B cell lymphoma from anti-IgM-mediated growth inhibition by up-regulation of egr-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histopathological and serological progression of experimental Staphylococcus aureus arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of cellular binding and uptake of antisense phosphodiester, phosphorothioate, and mixed phosphorothioate and methylphosphonate oligonucleotides.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear factor-kappa B is involved in the catecholaminergic suppression of immunocompetent cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble interleukin-6 receptor (sIL-6R) makes IL-6R negative T cell line respond to IL-6; it inhibits TNF production.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA activates human immune cells through a CpG sequence-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Now I know my CpGs

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6: an overview

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

What can we learn from the synovium in early rheumatoid arthritis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RANTES expression and contribution to monocyte chemotaxis in arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG oligodeoxynucleotides induce murine macrophages to up-regulate chemokine mRNA expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG-specific common commitment in caspase-dependent and -independent cell deaths

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism and function of a newly identified CpG DNA motif in human primary B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of Plasmid DNA to Inflammation in the Lung after Administration of Cationic Lipid:pDNA Complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proinflammatory and immunoregulatory functions of interleukin-12.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unmethylated oligo-DNA containing CpG motifs aggravates collagen-induced arthritis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG DNA rescue from anti-IgM-induced WEHI-231 B lymphoma apoptosis via modulation of I kappa B alpha and I kappa B beta and sustained activation of nuclear factor-kappa B/c-Rel

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice with the xid B cell defect are less susceptible to developing Staphylococcus aureus-induced arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular characterization of interleukin 12

1 reference

https://pubmed.ncbi.nlm.nih.gov/15072229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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