(Q47827840)

English

A basic amino acid in the cytoplasmic domain of Alzheimer's beta-amyloid precursor protein (APP) is essential for cleavage of APP at the alpha-site.

scientific article published in July 1998

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scholarly article

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Europe PubMed Central

PubMed publication ID

6 February 2018

http://europepmc.org/abstract/MED/9668120

A basic amino acid in the cytoplasmic domain of Alzheimer's beta-amyloid precursor protein (APP) is essential for cleavage of APP at the alpha-site. (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 February 2018

http://europepmc.org/abstract/MED/9668120

Alzheimer's disease

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author name string

Tomita S

1

1 reference

Europe PubMed Central

PubMed publication ID

6 February 2018

http://europepmc.org/abstract/MED/9668120

Kirino Y

2

1 reference

Europe PubMed Central

PubMed publication ID

6 February 2018

http://europepmc.org/abstract/MED/9668120

Suzuki T

3

1 reference

Europe PubMed Central

PubMed publication ID

6 February 2018

http://europepmc.org/abstract/MED/9668120

language of work or name

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publication date

1 July 1998

1 reference

Europe PubMed Central

PubMed publication ID

6 February 2018

http://europepmc.org/abstract/MED/9668120

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

6 February 2018

http://europepmc.org/abstract/MED/9668120

273

1 reference

Europe PubMed Central

PubMed publication ID

6 February 2018

http://europepmc.org/abstract/MED/9668120

30

1 reference

Europe PubMed Central

PubMed publication ID

6 February 2018

http://europepmc.org/abstract/MED/9668120

19304-19310

1 reference

Europe PubMed Central

PubMed publication ID

6 February 2018

http://europepmc.org/abstract/MED/9668120

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

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Amyloid plaque core protein in Alzheimer disease and Down syndrome

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Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease

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21 January 2018

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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21 January 2018

Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides

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21 January 2018

Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus

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21 January 2018

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

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21 January 2018

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

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Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

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21 January 2018

A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein

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21 January 2018

beta-Amyloid formation as a potential therapeutic target for Alzheimer's disease

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21 January 2018

Alzheimer's disease: a central role for amyloid

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21 January 2018

Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

1 reference

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21 January 2018

Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway

1 reference

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21 January 2018

The Alzheimer beta-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells

1 reference

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21 January 2018

Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus

1 reference

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21 January 2018

Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

1 reference

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21 January 2018

Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation

1 reference

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21 January 2018

Phosphorylation of Alzheimer amyloid precursor protein by protein kinase C.

1 reference

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21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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21 January 2018

Cleavage of amyloid beta peptide during constitutive processing of its precursor

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21 January 2018

Excessive production of amyloid beta-protein by peripheral cells of symptomatic and presymptomatic patients carrying the Swedish familial Alzheimer disease mutation

1 reference

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21 January 2018

Potentially Amyloidogenic, Carboxyl-Terminal Derivatives of the Amyloid Protein Precursor

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21 January 2018

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

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21 January 2018

Novel β-Secretase Cleavage of β-Amyloid Precursor Protein in the Endoplasmic Reticulum/Intermediate Compartment of NT2N Cells

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21 January 2018

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

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21 January 2018

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

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21 January 2018

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

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21 January 2018

A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

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21 January 2018

Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

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21 January 2018

Regulated cleavage of Alzheimer beta-amyloid precursor protein in the absence of the cytoplasmic tail

1 reference

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21 January 2018

Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein

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21 January 2018

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

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21 January 2018

Identifiers

10.1074/JBC.273.30.19304

1 reference

Europe PubMed Central

PubMed publication ID

6 February 2018

http://europepmc.org/abstract/MED/9668120

release_ardbd4cvjbb25aoqq5tsczy3mq

1 reference

https://api.fatcat.wiki/v0/release/ardbd4cvjbb25aoqq5tsczy3mq

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 February 2018

http://europepmc.org/abstract/MED/9668120

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