(Q47831493)

6 February 2018

title

Synthesis of the protein phosphatase 2A inhibitor (4S,5S,6S,10S,11S,12S)-cytostatin (English)

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6 February 2018

2

Herbert Waldmann

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6 February 2018

author name string

Laurent Bialy

series ordinal

1

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6 February 2018

publication date

1 May 2002

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6 February 2018

published in

Angewandte Chemie

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6 February 2018

volume

41

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6 February 2018

issue

10

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6 February 2018

page(s)

1748-1751

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6 February 2018

Signaling--2000 and beyond

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Chemical inhibitors of protein kinases

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Protein tyrosine phosphatases: prospects for therapeutics

21 January 2018

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Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25.

21 January 2018

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Potent reversible inhibitors of the protein tyrosine phosphatase CD45.

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Inhibition of the Ser-Thr phosphatases PP1 and PP2A by naturally occurring toxins

21 January 2018

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Natural products are biologically validated starting points in structural space for compound library development: solid-phase synthesis of dysidiolide-derived phosphatase inhibitors

21 January 2018

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Differential induction of apoptosis in B16 melanoma and EL-4 lymphoma cells by cytostatin and bactobolin.

21 January 2018

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Total synthesis of fostriecin (CI-920).

21 January 2018

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Total Synthesis of Fostriecin (CI-920) We thank Professor Andrew G. Myers and Scott E. Schaus for helpful discussions, and Dr. Alexandra E. Gould and Isabel K. Reichardt for important preliminary experimental work. We also thank Dr. Robert J. Schult

21 January 2018

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Highly enantioselective borane reduction of ketones catalyzed by chiral oxazaborolidines. Mechanism and synthetic implications

21 January 2018

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Enantioselective aldol condensations. 2. Erythro-selective chiral aldol condensations via boron enolates

21 January 2018

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The total synthesis of the polyether antibiotic X-206

21 January 2018

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Cytostatin, a novel inhibitor of cell adhesion to components of extracellular matrix produced by Streptomyces sp. MJ654-NF4. I. Taxonomy, fermentation, isolation and biological activities.

21 January 2018

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Novel antitumor agents CI-920, PD 113 270, and PD 113 271. 3. Structure determination

21 January 2018

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Direct synthesis of Z-unsaturated esters. A useful modification of the horner-emmons olefination

21 January 2018

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Dysidiolide and related gamma-hydroxy butenolide compounds as inhibitors of the protein tyrosine phosphatase, CDC25

21 January 2018

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Synthesis of the novel analogues of dysidiolide and their structure-activity relationship

21 January 2018

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Cytostatin, an inhibitor of cell adhesion to extracellular matrix, selectively inhibits protein phosphatase 2A

21 January 2018

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Inhibitory effect of cytostatin on spontaneous lung metastases of B16-BL6 melanoma cells

21 January 2018

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Cytostatin, a novel inhibitor of cell adhesion to components of extracellular matrix produced by Streptomyces sp. MJ654-NF4. II. Physico-chemical properties and structure determination

21 January 2018

1 reference

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Novel microbial metabolites of the phoslactomycins family induce production of colony-stimulating factors by bone marrow stromal cells. II. Isolation, physico-chemical properties and structure determination

21 January 2018

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Asymmetric Reduction. A Convenient Method for the Reduction of Alkynyl Ketones

21 January 2018

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Highly Enantioenriched Propargylic Alcohols by Oxazaborolidine-Mediated Reduction of Acetylenic Ketones

21 January 2018

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A useful 12-I-5 triacetoxyperiodinane (the Dess-Martin periodinane) for the selective oxidation of primary or secondary alcohols and a variety of related 12-I-5 species

21 January 2018

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10.1002/1521-3773(20020517)41:10<1748::AID-ANIE1748>3.0.CO;2-X

21 January 2018

Identifiers

DOI

1 reference

6 February 2018

1 reference

6 February 2018