(Q47833388)

6 February 2018

title

Artemisinin antimalarials moderately affect cytochrome P450 enzyme activity in healthy subjects (English)

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6 February 2018

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Sara Asimus

1

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6 February 2018

Doaa Elsherbiny

2

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6 February 2018

Trinh N Hai

3

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6 February 2018

Britt Jansson

4

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6 February 2018

Nguyen V Huong

5

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6 February 2018

Max G Petzold

6

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6 February 2018

Ulrika S H Simonsson

7

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6 February 2018

Michael Ashton

8

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6 February 2018

publication date

1 June 2007

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6 February 2018

Fundamental and Clinical Pharmacology

published in

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6 February 2018

volume

21

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6 February 2018

issue

3

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6 February 2018

page(s)

307-316

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6 February 2018

Artemisinin kinetics and dynamics during oral and rectal treatment of uncomplicated malaria

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2007.00471.X

Multiple dose pharmacokinetics of oral artemisinin and comparison of its efficacy with that of oral artesunate in falciparum malaria patients

21 January 2018

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Multiple dose pharmacokinetics of artemether in Chinese patients with uncomplicated falciparum malaria

21 January 2018

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Artemisinin autoinduction is caused by involvement of cytochrome P450 2B6 but not 2C9.

21 January 2018

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Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor.

21 January 2018

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Artemisinin and thiabendazole are potent inhibitors of cytochrome P450 1A2 (CYP1A2) activity in humans

21 January 2018

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Identification of an antimalarial synthetic trioxolane drug development candidate

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1472-8206.2007.00471.X

Assessment of cytochrome P450 activity by a five-drug cocktail approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1472-8206.2007.00471.X

Isozyme-specific induction of low-dose aspirin on cytochrome P450 in healthy subjects

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1472-8206.2007.00471.X

Chloroquine modulation of specific metabolizing enzymes activities: investigation with selective five drug cocktail

21 January 2018

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Enantiospecific separation and quantitation of mephenytoin and its metabolites nirvanol and 4'-hydroxymephenytoin in human plasma and urine by liquid chromatography/tandem mass spectrometry.

21 January 2018

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Hepatitis A impairs the function of human hepatic CYP2A6 in vivo.

21 January 2018

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An optimized methodology for combined phenotyping and genotyping on CYP2D6 and CYP2C19.

21 January 2018

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In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentration

21 January 2018

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An interaction between the cytochrome P450 probe substrates chlorzoxazone (CYP2E1) and midazolam (CYP3A)

21 January 2018

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Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism.

21 January 2018

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The Karolinska cocktail for phenotyping of five human cytochrome P450 enzymes.

21 January 2018

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A 'cocktail' strategy to assess in vivo oxidative drug metabolism in humans

21 January 2018

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Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin

21 January 2018

1 reference

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CYP2A6: a human coumarin 7-hydroxylase

21 January 2018

1 reference

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The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes

21 January 2018

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10.1111/J.1472-8206.2007.00471.X

21 January 2018

Identifiers

DOI

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6 February 2018

1 reference

6 February 2018