(Q47833552)

6 February 2018

title

The N-terminal extracellular domain is required for polycystin-1-dependent channel activity (English)

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6 February 2018

author name string

Victor Babich

1

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6 February 2018

Wei-Zhong Zeng

2

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6 February 2018

Byung-Il Yeh

3

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6 February 2018

Oxana Ibraghimov-Beskrovnaya

4

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6 February 2018

Yiqiang Cai

5

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6 February 2018

Stefan Somlo

6

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6 February 2018

Chou-Long Huang

7

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6 February 2018

language of work or name

English

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publication date

1 April 2004

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6 February 2018

Journal of Biological Chemistry

published in

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6 February 2018

volume

279

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6 February 2018

issue

24

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6 February 2018

page(s)

25582-25589

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6 February 2018

PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Comparative analysis of the polycystic kidney disease 1 (PKD1) gene reveals an integral membrane glycoprotein with multiple evolutionary conserved domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

The sea urchin sperm receptor for egg jelly is a modular protein with extensive homology to the human polycystic kidney disease protein, PKD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Specific association of the gene product of PKD2 with the TRPC1 channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Polycystin-2 is a novel cation channel implicated in defective intracellular Ca(2+) homeostasis in polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Polycystin-2 is an intracellular calcium release channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

The cytoplasmic C-terminal fragment of polycystin-1 regulates a Ca2+-permeable cation channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Cardiac defects and renal failure in mice with targeted mutations in Pkd2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Polycystin: in vitro synthesis, in vivo tissue expression, and subcellular localization identifies a large membrane-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Strong homophilic interactions of the Ig-like domains of polycystin-1, the protein product of an autosomal dominant polycystic kidney disease gene, PKD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Identification and characterization of polycystin-2, the PKD2 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Polycystin-1, the product of the polycystic kidney disease 1 gene, co-localizes with desmosomes in MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Polycystin-1 interacts with intermediate filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Functional polycystin-1 expression is developmentally regulated during epithelial morphogenesis in vitro: downregulation and loss of membrane localization during cystogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Distinct subcellular expression of endogenous polycystin-2 in the plasma membrane and Golgi apparatus of MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gbetagamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

PKD1 interacts with PKD2 through a probable coiled-coil domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

The renal cell primary cilium functions as a flow sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

Interaction between RGS7 and polycystin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

The polycystic kidney disease 1 gene product modulates Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402829200

21 January 2018

Identifiers

DOI

10.1074/JBC.M402829200

1 reference

6 February 2018

1 reference

6 February 2018