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PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2
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scholarly article
1 reference
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PubMed
PubMed ID
12007403
retrieved
31 January 2017
title
PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2
(English)
1 reference
stated in
PubMed
PubMed ID
12007403
retrieved
31 January 2017
main subject
Polycystin 2, transient receptor potential cation channel
1 reference
stated in
GOA release 2020-03-11
Polycystin 1, transient receptor potential channel interacting
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GOA release 2020-03-11
author
Alessandra Boletta
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3
object named as
Alessandra Boletta
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PubMed
PubMed ID
12007403
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31 January 2017
author name string
Anil Kumar Bhunia
series ordinal
1
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PubMed
PubMed ID
12007403
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31 January 2017
Klaus Piontek
series ordinal
2
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PubMed
PubMed ID
12007403
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31 January 2017
Lijuan Liu
series ordinal
4
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PubMed
PubMed ID
12007403
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31 January 2017
Feng Qian
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
12007403
retrieved
31 January 2017
Pei Ning Xu
series ordinal
6
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stated in
PubMed
PubMed ID
12007403
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31 January 2017
F. Joseph Germino
series ordinal
7
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PubMed
PubMed ID
12007403
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31 January 2017
Gregory G. Germino
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8
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PubMed
PubMed ID
12007403
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31 January 2017
language of work or name
English
0 references
publication date
19 April 2002
1 reference
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PubMed
PubMed ID
12007403
retrieved
31 January 2017
published in
Cell
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stated in
PubMed
PubMed ID
12007403
retrieved
31 January 2017
volume
109
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PubMed
PubMed ID
12007403
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31 January 2017
page(s)
157–168
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PubMed
PubMed ID
12007403
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31 January 2017
issue
2
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PubMed
PubMed ID
12007403
retrieved
31 January 2017
cites work
Induction of epithelial tubules by growth factor HGF depends on the STAT pathway
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
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inferred from DOI database lookup
Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
STATs and gene regulation
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
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inferred from DOI database lookup
STAT signaling is active during early mammalian development.
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
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WAF1, a potential mediator of p53 tumor suppression
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
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The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. The European Polycystic Kidney Disease Consortium
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
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inferred from DOI database lookup
B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
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Autosomal dominant polycystic kidney disease
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
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Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2+-permeable nonselective cation channel
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
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Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The JAK-STAT pathway in Drosophila
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Strong homophilic interactions of the Ig-like domains of polycystin-1, the protein product of an autosomal dominant polycystic kidney disease gene, PKD1
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STATs: signal transducers and activators of transcription
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of differentiation antigens and growth-related genes in normal kidney, autosomal dominant polycystic kidney disease, and renal cell carcinoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of STAT-dependent pathways by growth factors and cytokines.
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Jaks and STATs: biological implications
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of Pkd1-targeted mutants reveals that loss of polycystin-1 causes cystogenesis and bone defects
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Jak2 is essential for signaling through a variety of cytokine receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PKD1 interacts with PKD2 through a probable coiled-coil domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of SH2-bbeta as a potent cytoplasmic activator of the tyrosine kinase Janus kinase 2.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A common nuclear signal transduction pathway activated by growth factor and cytokine receptors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional responses to polypeptide ligands: the JAK-STAT pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDK inhibitors: positive and negative regulators of G1-phase progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A unique glucose-dependent apoptotic pathway induced by c-Myc
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific association of the gene product of PKD2 with the TRPC1 channel
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations of PKD1 in ADPKD2 cysts suggest a pathogenic effect of trans-heterozygous mutations.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis and loss of renal tissue in polycystic kidney diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic inactivation of Pkd2 results in polycystic kidney disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Janus kinase family of protein tyrosine kinases and their role in signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900716-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0092-8674(02)00716-X
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4831510
OpenCitations bibliographic resource ID
4831510
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4831510
PubMed ID
12007403
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4831510
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