(Q47835919)

6 February 2018

title

A functional variant of IRS1 is associated with type 1 diabetes in families from the US and UK. (English)

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6 February 2018

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3

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6 February 2018

Suna Onengut-Gumuscu

series ordinal

2

object named as

Suna Onengut-Gumuscu

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6 February 2018

V Anne Morrison

1

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6 February 2018

publication date

1 April 2004

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6 February 2018

Molecular Genetics and Metabolism

published in

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6 February 2018

volume

81

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6 February 2018

issue

4

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6 February 2018

page(s)

291-294

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6 February 2018

Genetic liability of type 1 diabetes and the onset age among 22,650 young Finnish twin pairs: a nationwide follow-up study

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1 reference

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Gly972Arg variant in the insulin receptor substrate-1 gene and association with Type 2 diabetes: a meta-analysis of 27 studies

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2003.10.018

The Gly972-->Arg IRS-1 variant is associated with type 1 diabetes in continental Italy

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2003.10.018

Insulin secretory function is impaired in isolated human islets carrying the Gly(972)-->Arg IRS-1 polymorphism

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2003.10.018

The Gly972Arg polymorphism in the insulin receptor substrate-1 gene contributes to the variation in insulin secretion in normal glucose-tolerant humans

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2003.10.018

The Gly972-->Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2003.10.018

Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2003.10.018

Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms

7 January 2021

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Allele-sharing models: LOD scores and accurate linkage tests

7 January 2021

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A test for linkage and association in general pedigrees: the pedigree disequilibrium test

7 January 2021

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The common Arg972 polymorphism in insulin receptor substrate-1 causes apoptosis of human pancreatic islets

7 January 2021

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Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases

7 January 2021

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Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

7 January 2021

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Overexpression of insulin receptor substrate-1, but not insulin receptor substrate-2, protects a T cell hybridoma from activation-induced cell death

7 January 2021

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Transcription: tantalizing times for T cells

7 January 2021

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Challenges and strategies for investigating the genetic complexity of common human diseases

7 January 2021

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10.1016/J.YMGME.2003.10.018

7 January 2021

Identifiers

DOI

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6 February 2018

1 reference

6 February 2018