(Q47886776)

6 February 2018

title

Meeting report: 4th ISIRV antiviral group conference: Novel antiviral therapies for influenza and other respiratory viruses. (English)

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6 February 2018

2

Alicia M Fry

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6 February 2018

Jennifer McKimm-Breschkin

series ordinal

1

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publication date

9 February 2016

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6 February 2018

published in

Antiviral Research

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6 February 2018

volume

129

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6 February 2018

page(s)

21-38

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6 February 2018

Vaccine-induced anti-HA2 antibodies promote virus fusion and enhance influenza virus respiratory disease

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Exploitation of the catalytic site and 150 cavity for design of influenza A neuraminidase inhibitors

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A Randomized, Double-Blind, Placebo-Controlled Trial of Pleconaril for the Treatment of Neonates With Enterovirus Sepsis

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Mutational analysis of the binding pockets of the diketo acid inhibitor L-742,001 in the influenza virus PA endonuclease

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Motavizumab treatment of infants hospitalized with respiratory syncytial virus infection does not decrease viral load or severity of illness.

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Influence of antibodies and T cells on dengue disease outcome: insights from interferon receptor-deficient mouse models

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The TLR4 antagonist Eritoran protects mice from lethal influenza infection

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Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate

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Influenza A virus uses the aggresome processing machinery for host cell entry

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Updated guidance for palivizumab prophylaxis among infants and young children at increased risk of hospitalization for respiratory syncytial virus infection

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Validation of the wild-type influenza A human challenge model H1N1pdMIST: an A(H1N1)pdm09 dose-finding investigational new drug study

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Sirtuins are evolutionarily conserved viral restriction factors

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DAS181 treatment of hematopoietic stem cell transplant patients with parainfluenza virus lung disease requiring mechanical ventilation

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12 December 2020

A novel family of peptides with potent activity against influenza A viruses

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12 December 2020

Successful Treatment of Parainfluenza Virus Respiratory Tract Infection With DAS181 in 4 Immunocompromised Children

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12 December 2020

Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus

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Synergistic effect of nitazoxanide with neuraminidase inhibitors against influenza A viruses in vitro

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Structural Insights into Bunyavirus Replication and Its Regulation by the vRNA Promoter.

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Challenges and opportunities in developing respiratory syncytial virus therapeutics

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12 December 2020

Animal models of Middle East respiratory syndrome coronavirus infection

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12 December 2020

Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model

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12 December 2020

Structure of influenza A polymerase bound to the viral RNA promoter

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12 December 2020

An investigational antiviral drug, DAS181, effectively inhibits replication of zoonotic influenza A virus subtype H7N9 and protects mice from lethality

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12 December 2020

Neuraminidase inhibitors for influenza B virus infection: efficacy and resistance

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12 December 2020

Characterization of a respiratory syncytial virus L protein inhibitor

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12 December 2020

Use of influenza antiviral agents by ambulatory care clinicians during the 2012-2013 influenza season

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12 December 2020

Stepwise priming by acidic pH and a high K+ concentration is required for efficient uncoating of influenza A virus cores after penetration

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12 December 2020

A broadly neutralizing human monoclonal antibody is effective against H7N9.

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12 December 2020

The catalytic mechanism of human parainfluenza virus type 3 haemagglutinin-neuraminidase revealed

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12 December 2020

Crystallographic Fragment Screening and Structure-Based Optimization Yields a New Class of Influenza Endonuclease Inhibitors

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12 December 2020

Structure-based discovery of the novel antiviral properties of naproxen against the nucleoprotein of influenza A virus

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12 December 2020

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12 December 2020

Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution

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12 December 2020

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses

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12 December 2020

Serendipitous discovery of a potent influenza virus a neuraminidase inhibitor

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12 December 2020

A critical role for the sphingosine analog AAL-R in dampening the cytokine response during influenza virus infection

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12 December 2020

Antiviral activity of the MEK-inhibitor U0126 against pandemic H1N1v and highly pathogenic avian influenza virus in vitro and in vivo

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12 December 2020

Structure-based design of novel naproxen derivatives targeting monomeric nucleoprotein of Influenza A virus

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12 December 2020

Effects of human anti-spike protein receptor binding domain antibodies on severe acute respiratory syndrome coronavirus neutralization escape and fitness

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12 December 2020

Combination of MEK inhibitors and oseltamivir leads to synergistic antiviral effects after influenza A virus infection in vitro

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12 December 2020

Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus

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12 December 2020

Effect of nitazoxanide in adults and adolescents with acute uncomplicated influenza: a double-blind, randomised, placebo-controlled, phase 2b/3 trial

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12 December 2020

A Potent Anti-influenza Compound Blocks Fusion through Stabilization of the Prefusion Conformation of the Hemagglutinin Protein

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12 December 2020

Severe respiratory illness associated with a nationwide outbreak of enterovirus D68 in the USA (2014): a descriptive epidemiological investigation

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12 December 2020

Verdinexor, a novel selective inhibitor of nuclear export, reduces influenza a virus replication in vitro and in vivo.

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12 December 2020

Influenza A Virus N5 Neuraminidase Has an Extended 150-Cavity

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12 December 2020

Broadening of neutralization activity to directly block a dominant antibody-driven SARS-coronavirus evolution pathway

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12 December 2020

Evaluation of a Real-Time Reverse Transcription-PCR Assay for Detection of Enterovirus D68 in Clinical Samples from an Outbreak in New York State in 2014

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12 December 2020

A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus

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12 December 2020

Favipiravir (T-705), a novel viral RNA polymerase inhibitor

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12 December 2020

Structural basis for a class of nanomolar influenza A neuraminidase inhibitors

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12 December 2020

Classification and evolution of human rhinoviruses

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12 December 2020

Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials

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12 December 2020

Influenza viral load and peramivir kinetics after single administration and proposal of regimens for peramivir administration against resistant variants

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12 December 2020

Advances in antivirals for non-influenza respiratory virus infections

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12 December 2020

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

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12 December 2020

Influenza NS1 interacts with p53 and alters its binding to p53-responsive genes, in a promoter-dependent manner.

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12 December 2020

Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics

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12 December 2020

Phase 1 clinical trials of DAS181, an inhaled sialidase, in healthy adults

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12 December 2020

Real time enzyme inhibition assays provide insights into differences in binding of neuraminidase inhibitors to wild type and mutant influenza viruses

1 reference

12 December 2020

Preclinical activity of VX-787, a first-in-class, orally bioavailable inhibitor of the influenza virus polymerase PB2 subunit

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12 December 2020

Nitazoxanide: a first-in-class broad-spectrum antiviral agent

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12 December 2020

Oral GS-5806 activity in a respiratory syncytial virus challenge study.

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12 December 2020

Discovery of a novel, first-in-class, orally bioavailable azaindole inhibitor (VX-787) of influenza PB2

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12 December 2020

Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data.

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12 December 2020

A phase II study of DAS181, a novel host directed antiviral for the treatment of influenza infection

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12 December 2020

Treatment of resistant influenza virus infection in a hospitalized patient with cystic fibrosis with DAS181, a host-directed antiviral

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12 December 2020

New 7-methylguanine derivatives targeting the influenza polymerase PB2 cap-binding domain

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12 December 2020

Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza pH1N1 (2009) Polymerase

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12 December 2020

Small molecules VP-14637 and JNJ-2408068 inhibit respiratory syncytial virus fusion by similar mechanisms

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12 December 2020

The neuraminidases of MDCK grown human influenza A(H3N2) viruses isolated since 1994 can demonstrate receptor binding.

1 reference

12 December 2020

Mechanism of 150-cavity formation in influenza neuraminidase

1 reference

12 December 2020

DAS181, a novel sialidase fusion protein, protects mice from lethal avian influenza H5N1 virus infection.

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12 December 2020

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12 December 2020

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12 December 2020

Meetings of the WHO working group on surveillance of influenza antiviral susceptibility – Geneva, November 2011 and June 2012

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12 December 2020

In vitro activity of favipiravir and neuraminidase inhibitor combinations against oseltamivir-sensitive and oseltamivir-resistant pandemic influenza A (H1N1) virus.

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12 December 2020

Influenza, a One Health paradigm--novel therapeutic strategies to fight a zoonotic pathogen with pandemic potential.

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12 December 2020

Recent progress in designing inhibitors that target the drug-resistant M2 proton channels from the influenza A viruses.

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12 December 2020

An integrated biological approach to guide the development of metal-chelating inhibitors of influenza virus PA endonuclease

1 reference

12 December 2020

Catalytic mechanism and novel receptor binding sites of human parainfluenza virus type 3 hemagglutinin-neuraminidase (hPIV3 HN)

1 reference

12 December 2020

Association between the 2008-09 seasonal influenza vaccine and pandemic H1N1 illness during Spring-Summer 2009: four observational studies from Canada

1 reference

12 December 2020

1 reference

12 December 2020

Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge study

1 reference

12 December 2020

Supportive treatment for children with the common cold

1 reference

12 December 2020

10.1016/J.ANTIVIRAL.2016.01.012

Identifiers

DOI

1 reference

6 February 2018

PubMed ID

26872862

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6 February 2018