(Q47918567)

English

NEDDylation antagonizes ubiquitination of proliferating cell nuclear antigen and regulates the recruitment of polymerase η in response to oxidative DNA damage

scientific article published on 22 August 2017

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 June 2018

http://europepmc.org/abstract/PMC/5876183

NEDDylation antagonizes ubiquitination of proliferating cell nuclear antigen and regulates the recruitment of polymerase η in response to oxidative DNA damage (English)

1 reference

Europe PubMed Central

PMC publication ID

13 June 2018

http://europepmc.org/abstract/PMC/5876183

protein ubiquitination

1 reference

based on heuristic

inferred from title

protein neddylation

1 reference

based on heuristic

inferred from title

author name string

Junhong Guan

1

1 reference

Europe PubMed Central

PMC publication ID

13 June 2018

http://europepmc.org/abstract/PMC/5876183

Shuyu Yu

2

1 reference

Europe PubMed Central

PMC publication ID

13 June 2018

http://europepmc.org/abstract/PMC/5876183

Xiaofeng Zheng

3

1 reference

Europe PubMed Central

PMC publication ID

13 June 2018

http://europepmc.org/abstract/PMC/5876183

publication date

22 August 2017

1 reference

Europe PubMed Central

PMC publication ID

13 June 2018

http://europepmc.org/abstract/PMC/5876183

1 reference

Europe PubMed Central

PMC publication ID

13 June 2018

http://europepmc.org/abstract/PMC/5876183

9

1 reference

Europe PubMed Central

PMC publication ID

13 June 2018

http://europepmc.org/abstract/PMC/5876183

4

1 reference

Europe PubMed Central

PMC publication ID

13 June 2018

http://europepmc.org/abstract/PMC/5876183

365-379

1 reference

Europe PubMed Central

PMC publication ID

13 June 2018

http://europepmc.org/abstract/PMC/5876183

copyright license

Creative Commons Attribution 4.0 International

22 August 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

SENP8 limits aberrant neddylation of NEDD8 pathway components to promote cullin-RING ubiquitin ligase function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Characterization of human translesion DNA synthesis across a UV-induced DNA lesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Blockage of neddylation modification stimulates tumor sphere formation in vitro and stem cell differentiation and wound healing in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Protein neddylation: beyond cullin-RING ligases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Modification of PCNA by ISG15 plays a crucial role in termination of error-prone translesion DNA synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

RNF168-mediated H2A neddylation antagonizes ubiquitylation of H2A and regulates DNA damage repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Regulation of DNA damage responses by ubiquitin and SUMO.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

RNF111-dependent neddylation activates DNA damage-induced ubiquitination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

c-Cbl-mediated neddylation antagonizes ubiquitination and degradation of the TGF-β type II receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

NEDDylation controls the target specificity of E2F1 and apoptosis induction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

NEDDylation regulates E2F-1-dependent transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

The ubiquitin E1 enzyme Ube1 mediates NEDD8 activation under diverse stress conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Y-family DNA polymerases and their role in tolerance of cellular DNA damage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Recruitment of RPL11 at promoter sites of p53-regulated genes upon nucleolar stress through NEDD8 and in an Mdm2-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Radiosensitization of human pancreatic cancer cells by MLN4924, an investigational NEDD8-activating enzyme inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

The hMsh2-hMsh6 complex acts in concert with monoubiquitinated PCNA and Pol η in response to oxidative DNA damage in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

RAD18 transmits DNA damage signalling to elicit homologous recombination repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Principles of ubiquitin and SUMO modifications in DNA repair.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Origin and function of ubiquitin-like proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Function and regulation of protein neddylation. 'Protein modifications: beyond the usual suspects' review series

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Regulation of DNA repair throughout the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Ribosomal proteins are targets for the NEDD8 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

PCNA, the maestro of the replication fork

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Role of ubiquitin- and Ubl-binding proteins in cell signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Surviving the breakup: the DNA damage checkpoint.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Regulation of monoubiquitinated PCNA by DUB autocleavage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Genome maintenance mechanisms for preventing cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

hRAD30 mutations in the variant form of xeroderma pigmentosum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiquitin-conjugating activity to DNA damage sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 June 2018

DENEDDYLASE1 Protein Counters Automodification of Neddylating Enzymes to Maintain NEDD8 Protein Homeostasis in Arabidopsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 August 2018

ML3 is a NEDD8- and ubiquitin-modified protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 August 2018

Mdm2-mediated NEDD8 modification of TAp73 regulates its transactivation function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 August 2018

Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876183

14 August 2018

hCINAP is a novel regulator of ribosomal protein-HDM2-p53 pathway by controlling NEDDylation of ribosomal protein S14

1 reference

https://pubmed.ncbi.nlm.nih.gov/28831681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neddylation of a breast cancer-associated protein recruits a class III histone deacetylase that represses NFkappaB-dependent transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/28831681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S13238-017-0455-X

1 reference

Europe PubMed Central

PMC publication ID

13 June 2018

http://europepmc.org/abstract/PMC/5876183

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 June 2018

http://europepmc.org/abstract/PMC/5876183

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 June 2018

http://europepmc.org/abstract/PMC/5876183

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