(Q47933117)

6 February 2018

title

Malignant peripheral nerve sheath tumor cell invasion is facilitated by Src and aberrant CD44 expression (English)

1 reference

malignant peripheral nerve sheath tumor

30 December 2023

main subject

0 references

adult malignant schwannoma

1 reference

inferred from title

invasion facilitation

1 reference

1 reference

30 December 2023

author name string

Weiping Su

1

1 reference

6 February 2018

Mihaela Sin

2

1 reference

6 February 2018

Andrea Darrow

3

1 reference

6 February 2018

Larry S. Sherman

4

1 reference

PubMed ID

12730955

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12730955

30 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

PubMed ID

12730955

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12730955

30 December 2023

publication date

1 June 2003

1 reference

6 February 2018

full work available at URL

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fglia.10206

1 reference

https://onlinelibrary.wiley.com/doi/pdf/10.1002/glia.10206

30 December 2023

1 reference

30 December 2023

1 reference

6 February 2018

volume

42

1 reference

6 February 2018

page(s)

350-358

1 reference

6 February 2018

issue

4

1 reference

6 February 2018

Expression of p27(kip) and other cell cycle regulators in malignant peripheral nerve sheath tumors and neurofibromas: the emerging role of p27(kip) in malignant transformation of neurofibromas

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Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

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c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

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Clinical relevance of CD44 cell surface expression and MYCN gene amplification in neuroblastoma

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Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

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Epidermal growth factor receptor expression in neurofibromatosis type 1-related tumors and NF1 animal models

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p53 expression in neurofibroma and malignant peripheral nerve sheath tumor. An immunohistochemical study of sporadic and NF1-associated tumors

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Nf1-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: reversion of some phenotypes by an inhibitor of farnesyl protein transferase

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CD44 protein levels and its biological activity are regulated in Balb/c 3T3 fibroblasts by serum factors and by transformation with the ras but not with the sis oncogene

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Epidermal Growth Factor-induced DNA Synthesis

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7 January 2021

The ligand binding domain of the epidermal growth factor receptor is not required for receptor dimerization

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7 January 2021

AP-1-mediated invasion requires increased expression of the hyaluronan receptor CD44.

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7 January 2021

Somatic deletion of the neurofibromatosis type 1 gene in a neurofibrosarcoma supports a tumour suppressor gene hypothesis

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7 January 2021

p53 and Ki-67 proliferating cell nuclear antigen in benign and malignant peripheral nerve sheath tumors in children

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7 January 2021

Alterations at chromosome 17 loci in peripheral nerve sheath tumors

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7 January 2021

Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis

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7 January 2021

A novel inhibitor of the tyrosine kinase Src suppresses phosphorylation of its major cellular substrates and reduces bone resorption in vitro and in rodent models in vivo

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7 January 2021

A case of neurofibrosarcoma associated with neurofibromatosis: light microscopic, ultrastructural, immunohistochemical and biochemical investigations

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7 January 2021

CD44: structure, function, and association with the malignant process.

1 reference

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7 January 2021

Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation

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7 January 2021

NF1 deletions in S-100 protein-positive and negative cells of sporadic and neurofibromatosis 1 (NF1)-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors

1 reference

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7 January 2021

Differential NF1, p16, and EGFR patterns by interphase cytogenetics (FISH) in malignant peripheral nerve sheath tumor (MPNST) and morphologically similar spindle cell neoplasms

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7 January 2021

Chromosome 17 loss-of-heterozygosity studies in benign and malignant tumors in neurofibromatosis type 1

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7 January 2021

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7 January 2021

Identification of NF1 mutations in both alleles of a dermal neurofibroma

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7 January 2021

Confirmation of a double-hit model for the NF1 gene in benign neurofibromas

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7 January 2021

Mitotic recombination effects homozygosity for NF1 germline mutations in neurofibromas

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7 January 2021

Angiogenic and invasive properties of neurofibroma Schwann cells

1 reference

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7 January 2021

Overexpression of activated neu/erbB2 initiates immortalization and malignant transformation of immature Schwann cells in vitro.

1 reference

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7 January 2021

Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts

1 reference

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7 January 2021

CD44 enhances neuregulin signaling by Schwann cells

1 reference

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7 January 2021

Molecular genetic analysis of tumors in von Recklinghausen neurofibromatosis: loss of heterozygosity for chromosome 17.

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7 January 2021

Malignant schwannoma--clinical characteristics, survival, and response to therapy

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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1 reference

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7 January 2021

Ligand-independent dimer formation of epidermal growth factor receptor (EGFR) is a step separable from ligand-induced EGFR signaling

1 reference

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7 January 2021

Epidermal growth factor induces CD44 gene expression through a novel regulatory element in mouse fibroblasts

1 reference

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7 January 2021

CD44 expression is aberrant in benign Schwann cell tumors possessing mutations in the neurofibromatosis type 2, but not type 1, gene

49

1 reference

Farnesyltransferase inhibitors block the neurofibromatosis type I (NF1) malignant phenotype

30 December 2023

62

1 reference

30 December 2023

Identifiers

DOI

10.1002/GLIA.10206

1 reference

6 February 2018

PubMed ID

12730955

1 reference

6 February 2018