(Q47984887)

7 February 2018

title

Tetraspanin15 regulates cellular trafficking and activity of the ectodomain sheddase ADAM10. (English)

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7 February 2018

author

Ralf Schwanbeck

6

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7 February 2018

Michael Schwake

8

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7 February 2018

author name string

Johannes Prox

1

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7 February 2018

Michael Willenbrock

2

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7 February 2018

Silvio Weber

3

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7 February 2018

Tobias Lehmann

4

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7 February 2018

Dirk Schmidt-Arras

5

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7 February 2018

Paul Saftig

7

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7 February 2018

publication date

25 March 2012

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7 February 2018

Cellular and Molecular Life Sciences

published in

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7 February 2018

volume

69

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7 February 2018

page(s)

2919-2932

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7 February 2018

issue

17

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7 February 2018

https://scigraph.springernature.com/pub.10.1007/s00018-012-0960-2

exact match

0 references

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Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

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The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling

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Analysis of the gamma-secretase interactome and validation of its association with tetraspanin-enriched microdomains

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Constitutive alpha-secretase cleavage of the beta-amyloid precursor protein in the furin-deficient LoVo cell line: involvement of the pro-hormone convertase 7 and the disintegrin metalloprotease ADAM10.

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12 December 2020

ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase

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LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidase

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Tetraspanin12 regulates ADAM10-dependent cleavage of amyloid precursor protein

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The "a disintegrin and metalloprotease" (ADAM) family of sheddases: physiological and cellular functions

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Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion protein in vivo

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Profiling of the Tetraspanin Web of Human Colon Cancer Cells

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Functional domains in tetraspanin proteins

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The yeast split-ubiquitin membrane protein two-hybrid screen identifies BAP31 as a regulator of the turnover of endoplasmic reticulum-associated protein tyrosine phosphatase-like B

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ADAM proteases: protective role in Alzheimer's and prion diseases?

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Tetraspanin proteins as organisers of membrane microdomains and signalling complexes.

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An arginine stretch limits ADAM10 exit from the endoplasmic reticulum

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The tetraspanin superfamily: molecular facilitators

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Functional interplay between tetraspanins and proteases

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The search for alpha-secretase and its potential as a therapeutic approach to Alzheimer s disease

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12 December 2020

Tetraspanin functions and associated microdomains

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12 December 2020

ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles

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12 December 2020

Genomic structure and functional characterization of the human ADAM10 promoter

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12 December 2020

A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model

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12 December 2020

Regulation of the alpha-secretase ADAM10 by its prodomain and proprotein convertases.

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12 December 2020

Protein-protein interactions in the tetraspanin web.

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12 December 2020

Differential expression of five members of the ADAM family in the developing chicken brain.

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12 December 2020

Increased processing of APLP2 and APP with concomitant formation of APP intracellular domains in BDNF and retinoic acid-differentiated human neuroblastoma cells

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12 December 2020

Tetraspanins regulate ADAM10-mediated cleavage of TNF-alpha and epidermal growth factor

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12 December 2020

The canonical Notch signaling pathway: unfolding the activation mechanism

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12 December 2020

Two dileucine motifs mediate late endosomal/lysosomal targeting of transmembrane protein 192 (TMEM192) and a C-terminal cysteine residue is responsible for disulfide bond formation in TMEM192 homodimers

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12 December 2020

ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and beta-catenin nuclear signalling

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12 December 2020

Disease-causing mutations within the lysosomal integral membrane protein type 2 (LIMP-2) reveal the nature of binding to its ligand beta-glucocerebrosidase

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12 December 2020

Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase

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12 December 2020

Tetraspanins as regulators of protein trafficking

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12 December 2020

The role of ADAMs in disease pathophysiology

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12 December 2020

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

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12 December 2020

Upregulation of the alpha-secretase ADAM10--risk or reason for hope?

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12 December 2020

The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex

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Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans

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A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease

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12 December 2020

ADAM10 is essential for proteolytic activation of Notch during thymocyte development.

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12 December 2020

Specific tetraspanin functions

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12 December 2020

The "A Disintegrin And Metalloproteases" ADAM10 and ADAM17: novel drug targets with therapeutic potential?

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12 December 2020

Proprotein convertase activity contributes to the processing of the Alzheimer's beta-amyloid precursor protein in human cells: evidence for a role of the prohormone convertase PC7 in the constitutive alpha-secretase pathway

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12 December 2020

Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin

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12 December 2020

Constitutive activation of metalloproteinase ADAM10 in mantle cell lymphoma promotes cell growth and activates the TNFα/NFκB pathway

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12 December 2020

Synapse-associated protein-97 mediates alpha-secretase ADAM10 trafficking and promotes its activity

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12 December 2020

Yeast-based functional genomics and proteomics technologies: the first 15 years and beyond.

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12 December 2020

10.1007/S00018-012-0960-2

Identifiers

DOI

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7 February 2018

PubMed ID

22446748

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7 February 2018