(Q43259456)

17 November 2017

Analysis of the gamma-secretase interactome and validation of its association with tetraspanin-enriched microdomains (English)

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17 November 2017

10

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17 November 2017

An Staes

7

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Claude Boucheix

object named as

Claude Boucheix

11

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Piet Herdewijn

object named as

Piet Herdewijn

6

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Bart De Strooper

13

object named as

Bart De Strooper

1 reference

17 November 2017

Tomoko Wakabayashi

1

1 reference

17 November 2017

Katleen Craessaerts

2

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17 November 2017

Leen Bammens

3

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17 November 2017

Mostafa Bentahir

4

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17 November 2017

Filip Borgions

5

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17 November 2017

Evy Timmerman

8

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17 November 2017

Joël Vandekerckhove

9

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17 November 2017

Kris Gevaert

12

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17 November 2017

18 October 2009

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17 November 2017

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17 November 2017

11

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17 November 2017

11

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17 November 2017

1340-1346

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https://scigraph.springernature.com/pub.10.1038/ncb1978

17 November 2017

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cites work

Tetraspanins regulate ADAM10-mediated cleavage of TNF-alpha and epidermal growth factor

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB1978

Functional organization of the yeast proteome by systematic analysis of protein complexes

21 January 2018

1 reference

12 December 2020

Presenilin diversifies its portfolio.

1 reference

12 December 2020

Identification of signal peptide peptidase, a presenilin-type aspartic protease

1 reference

12 December 2020

Reconstitution of gamma-secretase activity

1 reference

12 December 2020

Glu(332) in the Nicastrin ectodomain is essential for gamma-secretase complex maturation but not for its activity

1 reference

12 December 2020

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

1 reference

12 December 2020

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

1 reference

12 December 2020

The role of presenilin cofactors in the gamma-secretase complex

1 reference

12 December 2020

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12 December 2020

Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria

1 reference

12 December 2020

Purification and characterization of the human gamma-secretase complex

1 reference

12 December 2020

Cholesterol-dependent gamma-secretase activity in buoyant cholesterol-rich membrane microdomains

1 reference

12 December 2020

Beta1 integrins show specific association with CD98 protein in low density membranes

1 reference

12 December 2020

Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms

1 reference

12 December 2020

Targeting of tetraspanin proteins--potential benefits and strategies

1 reference

12 December 2020

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

12 December 2020

Purification, pharmacological modulation, and biochemical characterization of interactors of endogenous human gamma-secretase

1 reference

12 December 2020

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

1 reference

12 December 2020

S-palmitoylation of gamma-secretase subunits nicastrin and APH-1

1 reference

12 December 2020

Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate

1 reference

12 December 2020

A cell biological perspective on Alzheimer's disease

1 reference

12 December 2020

A complex interaction pattern of CIS and SOCS2 with the leptin receptor

1 reference

12 December 2020

Lateral organization of membrane proteins: tetraspanins spin their web.

1 reference

12 December 2020

Cholesterol contributes to the organization of tetraspanin-enriched microdomains and to CD81-dependent infection by malaria sporozoites

1 reference

12 December 2020

Identification of a novel family of presenilin homologues

1 reference

12 December 2020

TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity

1 reference

12 December 2020

γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

1 reference

12 December 2020

CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production

1 reference

12 December 2020

Evaluation of prototype transmembrane 4 superfamily protein complexes and their relation to lipid rafts

1 reference

12 December 2020

Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

1 reference

12 December 2020

Tetraspanin functions and associated microdomains

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCB1978

1 reference

17 November 2017

1 reference