(Q47990678)

7 February 2018

title

The short isoform of PML-RARα activates the NRF2/HO-1 pathway through a direct interaction with NRF2. (English)

1 reference

7 February 2018

main subject

Promyelocytic leukemia

1 reference

Retinoic acid receptor, alpha

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

Yulong Li

1

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7 February 2018

Hongyan Wang

2

1 reference

7 February 2018

Xiu Jun Wang

3

1 reference

7 February 2018

Xiuwen Tang

4

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7 February 2018

language of work or name

English

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publication date

4 August 2017

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7 February 2018

published in

FEBS Letters

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7 February 2018

volume

591

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7 February 2018

page(s)

2859-2868

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7 February 2018

issue

18

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7 February 2018

Molecular basis of the Keap1-Nrf2 system.

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Different Electrostatic Potentials Define ETGE and DLG Motifs as Hinge and Latch in Oxidative Stress Response

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Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex

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21 January 2018

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Rexinoid inhibits Nrf2-mediated transcription through retinoid X receptor alpha.

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Retinoic acid synergizes ATO-mediated cytotoxicity by precluding Nrf2 activity in AML cells

21 January 2018

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21 January 2018

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The PML-retinoic acid receptor alpha translocation converts the receptor from an inhibitor to a retinoic acid-dependent activator of transcription factor AP-1

21 January 2018

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PML/RARalpha targets promoter regions containing PU.1 consensus and RARE half sites in acute promyelocytic leukemia

21 January 2018

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Identification of retinoic acid as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha

21 January 2018

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Trafficking of the transcription factor Nrf2 to promyelocytic leukemia-nuclear bodies: implications for degradation of NRF2 in the nucleus

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Oxaliplatin activates the Keap1/Nrf2 antioxidant system conferring protection against the cytotoxicity of anticancer drugs.

21 January 2018

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Methylated arsenic metabolites bind to PML protein but do not induce cellular differentiation and PML-RARα protein degradation

21 January 2018

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RXRα inhibits the NRF2-ARE signaling pathway through a direct interaction with the Neh7 domain of NRF2.

21 January 2018

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21 January 2018

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Cell-cycle regulation and dynamics of cytoplasmic compartments containing the promyelocytic leukemia protein and nucleoporins

21 January 2018

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Production and purification of lentiviral vectors

21 January 2018

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Missense mutations in PML-RARA are critical for the lack of responsiveness to arsenic trioxide treatment

21 January 2018

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The PML domain of PML-RARα blocks senescence to promote leukemia

21 January 2018

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HO-1 underlies resistance of AML cells to TNF-induced apoptosis

21 January 2018

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NF-kappaB-inhibited acute myeloid leukemia cells are rescued from apoptosis by heme oxygenase-1 induction

21 January 2018

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Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1

21 January 2018

1 reference

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Nrf2 activation ameliorates cytotoxic effects of arsenic trioxide in acute promyelocytic leukemia cells through increased glutathione levels and arsenic efflux from cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

21 January 2018

Identifiers

DOI

10.1002/1873-3468.12779

1 reference

7 February 2018

PubMed ID

28777872

1 reference

7 February 2018