(Q47991175)

English

Hypermethylation of the cell cycle inhibitor p15INK4b 3'-untranslated region interferes with its transcriptional regulation in primary lymphomas.

scientific article published in January 1999

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9927195%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

Hypermethylation of the cell cycle inhibitor p15INK4b 3'-untranslated region interferes with its transcriptional regulation in primary lymphomas (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9927195%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

hypermethylation

1 reference

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Ignacio Pérez de Castro

2

1 reference

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9 December 2019

5

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9 December 2019

author name string

Malumbres M

1

1 reference

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9 December 2019

Santos J

3

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9 December 2019

Fernández Piqueras J

4

1 reference

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9 December 2019

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publication date

1 January 1999

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9 December 2019

1 reference

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9 December 2019

18

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9 December 2019

2

1 reference

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9 December 2019

385-396

1 reference

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9 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.onc.1202299

0 references

Evidence for instability of mRNAs containing AUUUA motifs mediated through translation-dependent assembly of a > 20S degradation complex

1 reference

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Tissue-specific levels of human glucose-6-phosphate dehydrogenase correlate with methylation of specific sites at the 3' end of the gene

1 reference

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Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

1 reference

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Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

1 reference

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7 January 2021

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p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

1 reference

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7 January 2021

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Cdk inhibitors in development and cancer

1 reference

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7 January 2021

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Genomic imprinting of p57KIP2, a cyclin-dependent kinase inhibitor, in mouse

1 reference

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7 January 2021

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Translational control of p27Kip1 accumulation during the cell cycle

1 reference

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7 January 2021

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Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15

1 reference

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7 January 2021

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CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation

1 reference

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7 January 2021

based on heuristic

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A cell cycle regulator potentially involved in genesis of many tumor types

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Variation in the methylation profile and structure of Pax3 and Pax7 among different mouse strains and during expression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of DNA methylation in cancer genetic and epigenetics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

inferred from DOI database lookup

Transforming growth factor beta activates the promoter of cyclin-dependent kinase inhibitor p15INK4B through an Sp1 consensus site

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

inferred from DOI database lookup

Inactivation of the cyclin-dependent kinase inhibitor p15INK4b by deletion and de novo methylation with independence of p16INK4a alterations in murine primary T-cell lymphomas.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

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An AC-repeat adjacent to mouse Cdkn2B allows the detection of specific allelic losses in the p15INK4b and p16INK4a tumor suppressor genes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

inferred from DOI database lookup

Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

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Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

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5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

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Differential methylation of the ornithine carbamoyl transferase gene on active and inactive mouse X chromosomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

inferred from DOI database lookup

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

inferred from DOI database lookup

Stifled by inhibitions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

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Compilation of somatic mutations of the CDKN2 gene in human cancers: non-random distribution of base substitutions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

inferred from DOI database lookup

The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

inferred from DOI database lookup

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

inferred from DOI database lookup

X inactivation, differentiation, and DNA methylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

inferred from DOI database lookup

5-Methylcytosine, Gene Regulation, and Cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

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Transforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

inferred from DOI database lookup

Cancer cell cycles

1 reference

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7 January 2021

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Inhibitors of mammalian G1 cyclin-dependent kinases

1 reference

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7 January 2021

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Methylation of an ETS site in the intron enhancer of the keratin 18 gene participates in tissue-specific repression

1 reference

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7 January 2021

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Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter

1 reference

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7 January 2021

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Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202299

7 January 2021

based on heuristic

inferred from DOI database lookup

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