(Q48010414)

7 February 2018

title

Tight-binding inhibitors efficiently inactivate both reaction centers of monomeric Plasmodium falciparum glyoxalase 1. (English)

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7 February 2018

main subject

Plasmodium falciparum

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author name string

Miriam Urscher

1

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7 February 2018

Swati S More

2

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7 February 2018

Romy Alisch

3

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7 February 2018

Robert Vince

4

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7 February 2018

Marcel Deponte

5

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7 February 2018

language of work or name

English

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publication date

18 June 2012

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7 February 2018

published in

FEBS Journal

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7 February 2018

volume

279

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7 February 2018

issue

14

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7 February 2018

page(s)

2568-2578

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7 February 2018

Glyoxalase in diabetes, obesity and related disorders

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1 reference

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Glyoxalase in tumourigenesis and multidrug resistance

21 January 2018

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The glyoxalase system of malaria parasites--implications for cell biology and general glyoxalase research

21 January 2018

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Methylglyoxal metabolism in trypanosomes and leishmania

21 January 2018

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Glyoxalase inhibitors. A possible approach to anticancer agents

21 January 2018

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Inhibition of glyoxalase I: the first low-nanomolar tight-binding inhibitors.

21 January 2018

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The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I

21 January 2018

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The critical role of S-lactoylglutathione formation during methylglyoxal detoxification in Escherichia coli

21 January 2018

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Distinct subcellular localization in the cytosol and apicoplast, unexpected dimerization and inhibition of Plasmodium falciparum glyoxalases

21 January 2018

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Allosteric coupling of two different functional active sites in monomeric Plasmodium falciparum glyoxalase I.

21 January 2018

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New medicines to improve control and contribute to the eradication of malaria

21 January 2018

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Malaria's drug miracle in danger

21 January 2018

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That Was Then But This Is Now: Malaria Research in the Time of an Eradication Agenda

21 January 2018

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Plasmodium falciparum glyoxalase II: Theorell-Chance product inhibition patterns, rate-limiting substrate binding via Arg(257)/Lys(260), and unmasking of acid-base catalysis

21 January 2018

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Inhibition of proliferation of human leukaemia 60 cells by diethyl esters of glyoxalase inhibitors in vitro

21 January 2018

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S-(N-aryl-N-hydroxycarbamoyl)glutathione derivatives are tight-binding inhibitors of glyoxalase I and slow substrates for glyoxalase II.

21 January 2018

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Antimalarial activity in vitro of the glyoxalase I inhibitor diester, S-p-bromobenzylglutathione diethyl ester.

21 January 2018

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Characterization of the glyoxalases of the malarial parasite Plasmodium falciparum and comparison with their human counterparts

21 January 2018

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17 The kinetics of reversible tight-binding inhibition

21 January 2018

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Reduction kinetics of a flavin oxidoreductase LuxG from Photobacterium leiognathi (TH1): half-sites reactivity

21 January 2018

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Two novel monothiol glutaredoxins from Saccharomyces cerevisiae provide further insight into iron-sulfur cluster binding, oligomerization, and enzymatic activity of glutaredoxins

21 January 2018

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21 January 2018

Identifiers

DOI

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7 February 2018

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7 February 2018