(Q48025310)

7 February 2018

title

TRIM28 is an Epigenetic Barrier to Induced Pluripotent Stem Cell Reprogramming (English)

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7 February 2018

author name string

Denise Catherine Miles

1

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7 February 2018

Nienke Alexandra de Vries

2

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7 February 2018

Santiago Gisler

3

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Cor Lieftink

4

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7 February 2018

Waseem Akhtar

5

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7 February 2018

Ewa Gogola

6

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7 February 2018

Inka Pawlitzky

7

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Danielle Hulsman

8

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Ellen Tanger

9

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7 February 2018

Martijn Koppens

10

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7 February 2018

Roderick Leonardus Beijersbergen

11

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7 February 2018

Maarten van Lohuizen

12

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7 February 2018

publication date

28 June 2016

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7 February 2018

published in

Stem Cells

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7 February 2018

volume

35

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issue

1

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page(s)

147-157

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7 February 2018

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

cites work

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Reprogramming factor expression initiates widespread targeted chromatin remodeling

21 January 2018

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Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome

21 January 2018

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A molecular roadmap of reprogramming somatic cells into iPS cells

21 January 2018

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Butyrate promotes induced pluripotent stem cell generation

21 January 2018

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Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

21 January 2018

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Chromatin-modifying enzymes as modulators of reprogramming

21 January 2018

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Deterministic direct reprogramming of somatic cells to pluripotency

21 January 2018

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H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs

21 January 2018

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The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner.

21 January 2018

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Kdm2b promotes induced pluripotent stem cell generation by facilitating gene activation early in reprogramming

21 January 2018

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Reprogramming Roadblocks Are System Dependent

21 January 2018

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The histone chaperone CAF-1 safeguards somatic cell identity

21 January 2018

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Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential

21 January 2018

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The KAP1 corepressor functions to coordinate the assembly of de novo HP1-demarcated microenvironments of heterochromatin required for KRAB zinc finger protein-mediated transcriptional repression

21 January 2018

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KAP1 controls endogenous retroviruses in embryonic stem cells

21 January 2018

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TRIM28 represses transcription of endogenous retroviruses in neural progenitor cells.

21 January 2018

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Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency

21 January 2018

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Germline-specific expression of the Oct-4/green fluorescent protein (GFP) transgene in mice

21 January 2018

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Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53.

21 January 2018

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Reprogramming of murine and human somatic cells using a single polycistronic vector

21 January 2018

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A drug-inducible system for direct reprogramming of human somatic cells to pluripotency

21 January 2018

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Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.

21 January 2018

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Transcriptional landscape of repetitive elements in normal and cancer human cells

21 January 2018

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A comparative encyclopedia of DNA elements in the mouse genome

21 January 2018

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The demethylase JMJD2C localizes to H3K4me3-positive transcription start sites and is dispensable for embryonic development

21 January 2018

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Model-based analysis of ChIP-Seq (MACS)

21 January 2018

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Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression.

21 January 2018

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SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins

21 January 2018

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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

21 January 2018

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Systematic identification of factors for provirus silencing in embryonic stem cells

21 January 2018

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The Ink4/Arf locus is a barrier for iPS cell reprogramming

21 January 2018

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A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

21 January 2018

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TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells

21 January 2018

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Dynamic transcription of distinct classes of endogenous retroviral elements marks specific populations of early human embryonic cells

21 January 2018

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Embryonic development following somatic cell nuclear transfer impeded by persisting histone methylation

21 January 2018

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Microarray analysis of LTR retrotransposon silencing identifies Hdac1 as a regulator of retrotransposon expression in mouse embryonic stem cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/STEM.2453

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7 February 2018

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7 February 2018