(Q40674805)

22 September 2017

Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53. (English)

1 reference

22 September 2017

2

1 reference

22 September 2017

Annette M G Dirac

1

1 reference

PubMed ID

12551891

22 September 2017

language of work or name

English

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publication date

27 January 2003

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

278

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22 September 2017

11731-11734

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22 September 2017

14

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The serial cultivation of human diploid cell strains

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Immortalisation and transformation revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Cellular senescence: mitotic clock or culture shock?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

The effect of low oxygen tension on the in vitro-replicative life span of human diploid fibroblast cells and their transformed derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Historical claims and current interpretations of replicative aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Extended culture of mouse embryo cells without senescence: inhibition by serum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Accumulation of p16INK4a in mouse fibroblasts as a function of replicative senescence and not of retinoblastoma gene status

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Escape from premature senescence is not sufficient for oncogenic transformation by Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

p14ARF links the tumour suppressors RB and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

E2F transcriptional repressor complexes are critical downstream targets of p19(ARF)/p53-induced proliferative arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Cellular senescence as a tumor-suppressor mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Telomeres and senescence: ending the debate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Genes involved in senescence and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Stable suppression of tumorigenicity by virus-mediated RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Regulation of cellular senescence by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

Low oxygen concentration extends the lifespan of cultured human diploid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300023200

21 January 2018

Identifiers

DOI

10.1074/JBC.C300023200

1 reference

22 September 2017

1 reference

PubMed ID

12551891