(Q48081204)

8 February 2018

title

A lambda 1 transgene under the control of a heavy chain promoter and enhancer does not undergo somatic hypermutation. (English)

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8 February 2018

author name string

M Hengstschläger

series ordinal

1

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8 February 2018

M Williams

series ordinal

2

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8 February 2018

N Maizels

series ordinal

3

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8 February 2018

language of work or name

English

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publication date

1 July 1994

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8 February 2018

European Journal of Immunology

published in

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8 February 2018

volume

24

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8 February 2018

issue

7

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8 February 2018

page(s)

1649-1656

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8 February 2018

Distribution of mutations around rearranged heavy-chain antibody variable-region genes

cites work

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

V(D)J recombination: molecular biology and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

The role of somatic hypermutation in the generation of antibody diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Timing, genetic requirements and functional consequences of somatic hypermutation during B-cell development.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Mutation drift and repertoire shift in the maturation of the immune response

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Clusters of point mutations are found exclusively around rearranged antibody variable genes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Somatic hypermutation in 5' flanking regions of heavy chain antibody variable regions.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Somatic hypermutation of an immunoglobulin transgene in kappa transgenic mice.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Analysis of somatic mutations in kappa transgenes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Somatic hypermutation of immunoglobulin kappa may depend on sequences 3' of C kappa and occurs on passenger transgenes.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Lack of somatic mutation in a kappa light chain transgene.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

The importance of the 3'-enhancer region in immunoglobulin kappa gene expression

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Somatic hypermutation of an immunoglobulin mu heavy chain transgene

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Hypermutation is observed only in antibody H chain V region transgenes that have recombined with endogenous immunoglobulin H DNA: implications for the location of cis-acting elements required for somatic mutation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Analysis of a T cell receptor gene as a target of the somatic hypermutation mechanism

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Idiotypic analysis of the response of C57BL/6 mice to the (4-hydroxy-3-nitrophenyl)acetyl group

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Inherited Immunoglobulin Idiotypes of the Mouse

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Molecular basis of a mouse strain-specific anti-hapten response.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Structure of primary anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies in normal and idiotypically suppressed C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Palindromic sequences are associated with sites of DNA breakage during gene conversion

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Transcriptional regulatory elements stimulate recombination in extrachromosomal substrates carrying immunoglobulin switch-region sequences

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

A Mab to a unique cerebellar neuron generated by immunosuppression and rapid immunization

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Continuous cultures of fused cells secreting antibody of predefined specificity

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

The T-cell-independent immune response to the hapten NP uses a large repertoire of heavy chain genes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

DNA sequencing with chain-terminating inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Restricted association of V and J-C gene segments for mouse lambda chains

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

The maturation of the immune response

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Somatic variants of murine immunoglobulin λ light chains

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Comparison of somatic mutation frequency among immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Isotype exclusion and transgene down-regulation in immunoglobulin-λ transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Inhibition of immunoglobulin gene rearrangement by the expression of a lambda 2 transgene

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

A rearranged lambda 2 light gene chain retards but does not exclude kappa and lambda 1 expression

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

B-less: a strain of profoundly B cell-deficient mice expressing a human lambda transgene

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

A novel enhancer in the immunoglobulin lambda locus is duplicated and functionally independent of NF kappa B.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830240729

7 January 2021

Identifiers

DOI

10.1002/EJI.1830240729

1 reference

8 February 2018

PubMed ID

8026525

1 reference

8 February 2018