(Q48108671)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28719017%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

title

Contrasting sirtuin and poly(ADP-ribose)polymerase activities of selected 2,4,6-trisubstituted benzimidazoles (English)

1 reference

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25 March 2020

1

1 reference

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25 March 2020

Chun W. Mai

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28719017%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Felicia Fei-Lei Chung

5

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25 March 2020

Chin Fei Chee

7

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25 March 2020

author name string

Soo Choon Tan

2

1 reference

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25 March 2020

Chee-Onn Leong

4

1 reference

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25 March 2020

Yean Kee Lee

6

1 reference

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25 March 2020

Noorsaadah Abdul Rahman

8

1 reference

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25 March 2020

publication date

9 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28719017%20AND%20SRC:MED&resulttype=core&format=json

Chemical Biology and Drug Design

25 March 2020

published in

1 reference

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25 March 2020

volume

91

1 reference

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25 March 2020

issue

1

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25 March 2020

page(s)

213-219

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28719017%20AND%20SRC:MED&resulttype=core&format=json

The Sir2 family of protein deacetylases

25 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Sirtuins: Sir2-related NAD-dependent protein deacetylases

21 January 2018

1 reference

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Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

21 January 2018

Sirtuins at a glance.

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Sirtuins: critical regulators at the crossroads between cancer and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

The dual role of sirtuins in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling

21 January 2018

1 reference

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Linking SIRT2 to Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

SIRT1 is significantly elevated in mouse and human prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1.

21 January 2018

1 reference

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Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease

21 January 2018

1 reference

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Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator.

21 January 2018

1 reference

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Synthesis and evaluation of novel benzimidazole derivatives as sirtuin inhibitors with antitumor activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Benzimidazoles as new scaffold of sirtuin inhibitors: green synthesis, in vitro studies, molecular docking analysis and evaluation of their anti-cancer properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Antagonistic crosstalk between SIRT1, PARP-1, and -2 in the regulation of chronic inflammation associated with aging and metabolic diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Synthesis and evaluation of a new generation of orally efficacious benzimidazole-based poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors as anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Mechanisms Underlying the Anti-Inflammatory Effects of Clinacanthus nutans Lindau Extracts: Inhibition of Cytokine Production and Toll-Like Receptor-4 Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Chalcones with electron-withdrawing and electron-donating substituents: anticancer activity against TRAIL resistant cancer cells, structure-activity relationship analysis and regulation of apoptotic proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Crystal structure analysis of human Sirt2 and its ADP-ribose complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Design, synthesis, and biological evaluation of a series of benzo[de][1,7]naphthyridin-7(8H)-ones bearing a functionalized longer chain appendage as novel PARP1 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Crystal structure of a SIR2 homolog-NAD complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Cardiotoxicity of the antiproliferative compound fluorouracil

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Sirtuins are Unaffected by PARP Inhibitors Containing Planar Nicotinamide Bioisosteres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Pharmacodynamic effects of seliciclib, an orally administered cell cycle modulator, in undifferentiated nasopharyngeal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

The significance of LMP1 expression in nasopharyngeal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

Positive regulation of HIF-1A expression by EBV oncoprotein LMP1 in nasopharyngeal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

AK-1, a SIRT2 inhibitor, destabilizes HIF-1α and diminishes its transcriptional activity during hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.13072

21 January 2018

Identifiers

DOI

10.1111/CBDD.13072

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28719017%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference