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Sirtuins at a glance.
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1 reference
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Europe PubMed Central
PMC publication ID
3048886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21378304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
title
Sirtuins at a glance
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3048886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21378304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
author
Takashi Nakagawa
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3048886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21378304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
Leonard P. Guarente
series ordinal
2
object named as
Leonard Guarente
1 reference
stated in
Europe PubMed Central
PMC publication ID
3048886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21378304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
language of work or name
English
0 references
publication date
1 March 2011
1 reference
stated in
Europe PubMed Central
PMC publication ID
3048886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21378304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
published in
Journal of Cell Science
1 reference
stated in
Europe PubMed Central
PMC publication ID
3048886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21378304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
volume
124
1 reference
stated in
Europe PubMed Central
PMC publication ID
3048886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21378304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
issue
Pt 6
1 reference
stated in
Europe PubMed Central
PMC publication ID
3048886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21378304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
page(s)
833-838
1 reference
stated in
Europe PubMed Central
PMC publication ID
3048886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21378304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
cites work
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction
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Silent information regulator 1 protects the heart from ischemia/reperfusion
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SIRT6 deficiency results in severe hypoglycemia by enhancing both basal and insulin-stimulated glucose uptake in mice
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27 May 2018
Human SIRT6 promotes DNA end resection through CtIP deacetylation
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27 May 2018
Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis
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SIRT4 regulates fatty acid oxidation and mitochondrial gene expression in liver and muscle cells
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27 May 2018
SIRT1 Regulates Thyroid-Stimulating Hormone Release by Enhancing PIP5Kgamma Activity through Deacetylation of Specific Lysine Residues in Mammals
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27 May 2018
SIRT1 Promotes the Central Adaptive Response to Diet Restriction through Activation of the Dorsomedial and Lateral Nuclei of the Hypothalamus
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27 May 2018
SIRT1 is essential for normal cognitive function and synaptic plasticity
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27 May 2018
SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10.
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27 May 2018
A novel pathway regulates memory and plasticity via SIRT1 and miR-134
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27 May 2018
SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity
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27 May 2018
Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha
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27 May 2018
Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
Hypothalamic Sirt1 regulates food intake in a rodent model system
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
SIRT1 genetic variation is related to BMI and risk of obesity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6.
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PubMed Central
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27 May 2018
SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
Regulation of hypoxia-inducible factor 2alpha signaling by the stress-responsive deacetylase sirtuin 1.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis
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PubMed Central
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27 May 2018
Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
SirT1 gain of function increases energy efficiency and prevents diabetes in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Sirt1 protects against high-fat diet-induced metabolic damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Negative regulation of the deacetylase SIRT1 by DBC1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
DBC1 is a negative regulator of SIRT1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
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27 May 2018
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
SIRT1 deacetylates and positively regulates the nuclear receptor LXR
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Sirtuin 2, a mammalian homolog of yeast silent information regulator-2 longevity regulator, is an oligodendroglial protein that decelerates cell differentiation through deacetylating alpha-tubulin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Resveratrol improves health and survival of mice on a high-calorie diet
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Sir2 mediates longevity in the fly through a pathway related to calorie restriction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Mammalian SIRT1 represses forkhead transcription factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
The possible implication of trans-Resveratrol in the cardioprotective effects of long-term moderate wine consumption
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Negative control of p53 by Sir2alpha promotes cell survival under stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
27 May 2018
Overexpression of SIRT5 confirms its involvement in deacetylation and activation of carbamoyl phosphate synthetase 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
16 August 2018
SIRT1 genetic variation and mortality in type 2 diabetes: interaction with smoking and dietary niacin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
16 August 2018
Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
16 August 2018
Sirt1 regulates aging and resistance to oxidative stress in the heart
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
16 August 2018
Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048886
retrieved
16 August 2018
Identifiers
DOI
10.1242/JCS.081067
1 reference
stated in
Europe PubMed Central
PMC publication ID
3048886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21378304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
PMC publication ID
3048886
1 reference
stated in
Europe PubMed Central
PMC publication ID
3048886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21378304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
PubMed publication ID
21378304
1 reference
stated in
Europe PubMed Central
PMC publication ID
3048886
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21378304%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
ResearchGate publication ID
50289493
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