(Q48117303)

8 February 2018

title

Peripheral transgene expression of plasma gelsolin reduces amyloid in transgenic mouse models of Alzheimer's disease (English)

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8 February 2018

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Aaron C Hirko

1

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8 February 2018

Edwin M Meyer

series ordinal

2

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8 February 2018

Michael A King

series ordinal

3

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8 February 2018

Jeffery A Hughes

series ordinal

4

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8 February 2018

publication date

3 July 2007

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8 February 2018

published in

Molecular Therapy

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8 February 2018

volume

15

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8 February 2018

issue

9

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8 February 2018

page(s)

1623-1629

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8 February 2018

The deposition of amyloid proteins in the aging mammalian brain: implications for Alzheimer's disease

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Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

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RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

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Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

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7 January 2021

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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7 January 2021

Comparative analysis of an improved thioflavin-s stain, Gallyas silver stain, and immunohistochemistry for neurofibrillary tangle demonstration on the same sections.

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7 January 2021

Quantitative histological analysis of amyloid deposition in Alzheimer's double transgenic mouse brain.

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7 January 2021

Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease.

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7 January 2021

Abeta peptide immunization restores blood-brain barrier integrity in Alzheimer disease.

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7 January 2021

Gelsolin inhibits the fibrillization of amyloid beta-protein, and also defibrillizes its preformed fibrils

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7 January 2021

Beta-amyloid stimulates murine postnatal and adult microglia cultures in a unique manner.

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7 January 2021

Relationship of plasma gelsolin levels to outcomes in critically ill surgical patients

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Gelsolin Secretion in Interleukin-4–treated Bronchial Epithelia and in Asthmatic Airways

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7 January 2021

Prognostic implications of declining plasma gelsolin levels after allogeneic stem cell transplantation

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7 January 2021

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Brain-derived neurotrophic factor in astrocytes, oligodendrocytes, and microglia/macrophages after spinal cord injury.

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7 January 2021

Neurotrophin secretion from cultured microglia

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7 January 2021

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

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7 January 2021

Ineffective phagocytosis of amyloid-beta by macrophages of Alzheimer's disease patients.

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7 January 2021

Expression of scavenger receptors in glial cells. Comparing the adhesion of astrocytes and microglia from neonatal rats to surface-bound beta-amyloid

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7 January 2021

Amyloid-beta immunization effectively reduces amyloid deposition in FcRgamma-/- knock-out mice

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7 January 2021

Intrahippocampal LPS injections reduce Abeta load in APP+PS1 transgenic mice

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7 January 2021

Time-dependent reduction in Abeta levels after intracranial LPS administration in APP transgenic mice.

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7 January 2021

Intracranially Administered Anti-Αβ Antibodies Reduce β-Amyloid Deposition by Mechanisms Both Independent of and Associated with Microglial Activation

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7 January 2021

Hope for AD with NGF gene-therapy trial

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7 January 2021

NGF gene transfer to intrinsic basal forebrain neurons increases cholinergic cell size and protects from age-related, spatial memory deficits in middle-aged rats

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7 January 2021

The effects of rAAV2-mediated NGF gene delivery in adult and aged rats

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7 January 2021

The effect of systemically administered recombinant human nerve growth factor in healthy human subjects

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7 January 2021

Insulin-degrading enzyme: stable expression of the human complementary DNA, characterization of its protein product, and chromosomal mapping of the human and mouse genes

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7 January 2021

Rapid intravascular injection into limb skeletal muscle: a damage assessment study.

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7 January 2021

Identification of critical functional and regulatory domains in gelsolin

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7 January 2021

Dose and promoter effects of adeno-associated viral vector for green fluorescent protein expression in the rat brain.

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7 January 2021

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

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7 January 2021

Long-Term Neuronal Effects and Disposition of Ectopic preproNGF Gene Transfer into the Rat Septum

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7 January 2021

Multiple calcium channels and kinases mediate alpha7 nicotinic receptor neuroprotection in PC12 cells

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7 January 2021

beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300253

7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300253

1 reference

8 February 2018

1 reference

8 February 2018