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UbMES and UbFluor: Novel probes for ring-between-ring (RBR) E3 ubiquitin ligase PARKIN.
scientific article published on 14 July 2017
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Europe PubMed Central
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5633118
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28710279%20AND%20SRC:MED&resulttype=core&format=json
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25 March 2020
title
UbMES and UbFluor: Novel probes for ring-between-ring (RBR) E3 ubiquitin ligase PARKIN
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
5633118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28710279%20AND%20SRC:MED&resulttype=core&format=json
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25 March 2020
author
David T Krist
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3
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5633118
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28710279%20AND%20SRC:MED&resulttype=core&format=json
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25 March 2020
Alexander V Statsyuk
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5
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Europe PubMed Central
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5633118
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28710279%20AND%20SRC:MED&resulttype=core&format=json
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25 March 2020
author name string
Sungjin Park
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1
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5633118
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28710279%20AND%20SRC:MED&resulttype=core&format=json
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25 March 2020
Peter K Foote
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2
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5633118
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28710279%20AND%20SRC:MED&resulttype=core&format=json
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25 March 2020
Sarah E Rice
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4
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5633118
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28710279%20AND%20SRC:MED&resulttype=core&format=json
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25 March 2020
language of work or name
English
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publication date
14 July 2017
1 reference
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Europe PubMed Central
PMC publication ID
5633118
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28710279%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
published in
Journal of Biological Chemistry
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Europe PubMed Central
PMC publication ID
5633118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28710279%20AND%20SRC:MED&resulttype=core&format=json
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25 March 2020
volume
292
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Europe PubMed Central
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5633118
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25 March 2020
issue
40
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Europe PubMed Central
PMC publication ID
5633118
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28710279%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
page(s)
16539-16553
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Europe PubMed Central
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5633118
reference URL
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25 March 2020
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Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation.
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Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy.
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Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.
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29 September 2018
The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy
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29 September 2018
Ubiquitin is phosphorylated by PINK1 to activate parkin
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29 September 2018
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
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29 September 2018
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Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity
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Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3
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Label free fragment screening using surface plasmon resonance as a tool for fragment finding - analyzing parkin, a difficult CNS target
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Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
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Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation.
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Structure of the human Parkin ligase domain in an autoinhibited state
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29 September 2018
Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism
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29 September 2018
Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism
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29 September 2018
Structure of parkin reveals mechanisms for ubiquitin ligase activation
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29 September 2018
Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming
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29 September 2018
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
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29 September 2018
PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding
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29 September 2018
PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
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29 September 2018
ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons.
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29 September 2018
Overexpression of parkin ameliorates dopaminergic neurodegeneration induced by 1- methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice
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29 September 2018
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
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29 September 2018
PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility
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29 September 2018
Autoregulation of Parkin activity through its ubiquitin-like domain
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29 September 2018
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids
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29 September 2018
The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
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29 September 2018
Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin
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29 September 2018
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
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29 September 2018
Molecular determinants of microbial resistance to thiopeptide antibiotics.
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29 September 2018
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
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29 September 2018
Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex
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29 September 2018
A disease state mutation unfolds the parkin ubiquitin-like domain.
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Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs
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29 September 2018
Catalytic efficiency and kcat/KM: a useful comparator?
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29 September 2018
DJ-1 and Parkin modulate dopamine-dependent behavior and inhibit MPTP-induced nigral dopamine neuron loss in mice
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29 September 2018
Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity
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29 September 2018
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
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29 September 2018
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
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29 September 2018
Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin.
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29 September 2018
Pathogenic mutations inactivate parkin by distinct mechanisms.
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29 September 2018
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
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29 September 2018
Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5633118
retrieved
29 September 2018
Association between early-onset Parkinson's disease and mutations in the parkin gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5633118
retrieved
29 September 2018
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5633118
retrieved
29 September 2018
Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/28710279
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Alpha-chymotrypsin: enzyme concentration and kinetics
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/28710279
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1074/JBC.M116.773200
1 reference
stated in
Europe PubMed Central
PMC publication ID
5633118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28710279%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
Fatcat ID
release_bcnxgd4jrrbpvnq2rcmatpmuye
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/bcnxgd4jrrbpvnq2rcmatpmuye
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
5633118
1 reference
stated in
Europe PubMed Central
PMC publication ID
5633118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28710279%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
PubMed publication ID
28710279
1 reference
stated in
Europe PubMed Central
PMC publication ID
5633118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28710279%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
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