(Q48133104)

English

Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malig

scientific article published in October 2003

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scholarly article

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/14649883

Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malig (English)

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/14649883

Henry Seth Friedman

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Henry S Friedman

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Darell D. Bigner

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Darell D Bigner

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Allan H Friedman

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9 February 2018

David A Reardon

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David A Reardon

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Roger E McLendon

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object named as

Roger E McLendon

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http://europepmc.org/abstract/MED/14649883

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Jeremy Rich

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http://europepmc.org/abstract/MED/14649883

Jennifer J Quinn

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object named as

Jennifer Quinn

1 reference

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http://europepmc.org/abstract/MED/14649883

James H. Herndon

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James E Herndon

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http://europepmc.org/abstract/MED/14649883

Mitchel S. Berger

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Mitchel S Berger

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http://europepmc.org/abstract/MED/14649883

James M Provenzale

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James Provenzale

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http://europepmc.org/abstract/MED/14649883

Sandra Tourt-Uhlig

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Sandra Tourt-Uhlig

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http://europepmc.org/abstract/MED/14649883

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object named as

Kara Penne

1 reference

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http://europepmc.org/abstract/MED/14649883

Michael R Zalutsky

24

object named as

Michael R Zalutsky

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http://europepmc.org/abstract/MED/14649883

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object named as

Gamal Akabani

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Europe PubMed Central

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http://europepmc.org/abstract/MED/14649883

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Alison Paolino

1 reference

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9 February 2018

http://europepmc.org/abstract/MED/14649883

Carol J Wikstrand

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object named as

Carol Wikstrand

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http://europepmc.org/abstract/MED/14649883

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object named as

Sandeep Kunwar

1 reference

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9 February 2018

http://europepmc.org/abstract/MED/14649883

Timothy T Stenzel

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object named as

Timothy Stenzel

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http://europepmc.org/abstract/MED/14649883

25

object named as

Ira Pastan

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9 February 2018

http://europepmc.org/abstract/MED/14649883

author name string

John H Sampson

1

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Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/14649883

Gary E Archer

3

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http://europepmc.org/abstract/MED/14649883

Steve Marcus

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http://europepmc.org/abstract/MED/14649883

Terence Wong

21

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9 February 2018

http://europepmc.org/abstract/MED/14649883

Roger Williams

22

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Fan Yuan

23

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http://europepmc.org/abstract/MED/14649883

publication date

1 October 2003

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9 February 2018

http://europepmc.org/abstract/MED/14649883

Journal of Neuro-Oncology

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http://europepmc.org/abstract/MED/14649883

65

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http://europepmc.org/abstract/MED/14649883

1

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27-35

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https://scigraph.springernature.com/pub.10.1023/a:1026290315809

0 references

Transforming growth factor-alpha-Pseudomonas exotoxin fusion protein (TGF-alpha-PE38) treatment of subcutaneous and intracranial human glioma and medulloblastoma xenografts in athymic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I trial of the diphtheria toxin/interleukin-2 fusion protein DAB486IL-2: efficacy in mycosis fungoides and other non-Hodgkin's lymphomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intratumoral administration of recombinant circularly permuted interleukin-4-Pseudomonas exotoxin in patients with high-grade glioma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-flow microinfusion: tissue penetration and pharmacodynamics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of various methods for delivering radiolabeled monoclonal antibody to normal rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted therapy of cancer with recombinant immunotoxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Convection-enhanced delivery of macromolecules in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemotherapy for high-grade gliomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with recurrent malignant gliomas: phase I trial results

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunotoxins that target an oncogenic mutant epidermal growth factor receptor expressed in human tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic effects of genetically engineered toxin (DAB486IL-2) in patient with chronic lymphocytic leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Annual report to the nation on the status of cancer (1973 through 1998), featuring cancers with recent increasing trends

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor expression in human gliomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunotoxins and central nervous system neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterogeneity in interleukin-13 receptor expression and subunit structure in squamous cell carcinoma of head and neck: differential sensitivity to chimeric fusion proteins comprised of interleukin-13 and a mutated form of Pseudomonas exotoxin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrathecal administration of single-chain immunotoxin, LMB-7 [B3(Fv)-PE38], produces cures of carcinomatous meningitis in a rat model

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and tumor localization of 131I-labeled anti-tenascin monoclonal antibody 81C6 in patients with gliomas and other intracranial malignancies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant Toxins for Cancer Treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer surveillance series [corrected]: brain and other central nervous system cancers: recent trends in incidence and mortality.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibody and F(ab')2 fragment delivery to tumor in patients with glioma: comparison of intracarotid and intravenous administration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of epidermal growth factor receptors in human brain tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplification and expression of the epidermal growth factor receptor gene in human glioma xenografts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical evaluation of intraperitoneal Pseudomonas exotoxin immunoconjugate OVB3-PE in patients with ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I trial of a 90-minute infusion of the fusion toxin DAB486IL-2 in hematological cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxicity and antitumor effects of growth factor-toxin fusion proteins on human glioblastoma multiforme cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glioblastoma multiforme and anaplastic astrocytoma. Pathologic criteria and prognostic implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic interstitial infusion of protein to primate brain: determination of drug distribution and clearance with single-photon emission computerized tomography imaging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I trial of an interleukin-2 (IL-2) fusion toxin (DAB486IL-2) in hematologic malignancies expressing the IL-2 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of advanced solid tumors with immunotoxin LMB-1: an antibody linked to Pseudomonas exotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant toxins as novel therapeutic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I trial of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I trial of an interleukin-2 fusion toxin (DAB486IL-2) in hematologic malignancies: complete response in a patient with Hodgkin's disease refractory to chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of treatment on long-term survivors with malignant astrocytomas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14649883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1026290315809

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/14649883

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

9 February 2018

http://europepmc.org/abstract/MED/14649883

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