(Q48165359)

9 February 2018

title

A novel mechanism of action for hypertension control: moxonidine as a selective I1-imidazoline agonist (English)

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9 February 2018

main subject

arterial hypertension

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1

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9 February 2018

Musa A Haxhiu

2

object named as

M A Haxhiu

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9 February 2018

Ismail A Dreshaj

5

object named as

I Dreshaj

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9 February 2018

author name string

L M Graff

3

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9 February 2018

L A Collins

4

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9 February 2018

D L Grove

6

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9 February 2018

M E Graves

7

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9 February 2018

S G Schäfer

8

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9 February 2018

M O Christen

9

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9 February 2018

publication date

1 March 1994

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9 February 2018

Cardiovascular Drugs and Therapy

published in

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9 February 2018

volume

8 Suppl 1

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9 February 2018

page(s)

27-41

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9 February 2018

Evidence for the involvement of imidazoline receptors in the central hypotensive effect of rilmenidine in the rabbit

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF00877082

Naloxone reverses the antihypertensive effect of clonidine

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF00877082

Nonadrenergic modulation by clonidine of the cosecretion of catecholamines and enkephalins in adrenal chromaffin cells

21 January 2018

1 reference

12 December 2020

Localization of the central cardiovascular action of clonidine

1 reference

12 December 2020

Clonidine-specific antisera recognize an endogenous clonidine-displacing substance in brain

1 reference

12 December 2020

Effects of clonidine and other imidazole-receptor binding agents on second messenger systems and calcium influx in bovine adrenal chromaffin cells

1 reference

12 December 2020

Action of -adrenergic blocking drugs on the sympathetic centres and their interactions with the central sympatho-inhibitory effect of clonidine

1 reference

12 December 2020

Rilmenidine lowers arterial pressure via imidazole receptors in brainstem C1 area.

1 reference

12 December 2020

5-Hydroxytryptamine 5-HT1B and 5-HT1D receptors mediating inhibition of adenylate cyclase activity. Pharmacological comparison with special reference to the effects of yohimbine, rauwolscine and some beta-adrenoceptor antagonists

1 reference

12 December 2020

Characterization and visualization of clonidine-sensitive imidazole sites in rat kidney which recognize clonidine-displacing substance

1 reference

12 December 2020

Role of ventrolateral medulla in sympatholytic effect of 8-OHDPAT in rats

1 reference

12 December 2020

Neurochemical lesion of the locus coeruleus of the rat does not suppress the sedative effect of clonidine.

1 reference

12 December 2020

Evidence that locus coeruleus is the site where clonidine and drugs acting at alpha 1- and alpha 2-adrenoceptors affect sleep and arousal mechanisms

1 reference

12 December 2020

Differences in the ability of yohimbine to antagonize the hypotensive effect of clonidine in normotensive and spontaneously hypertensive anesthetized rats

1 reference

12 December 2020

Alpha-adrenergic drugs. Pharmacological tools for the study of the central vasomotor control

1 reference

12 December 2020

Analysis of radioligand binding experiments. A collection of computer programs for the IBM PC.

1 reference

12 December 2020

.alpha.2 Adrenoceptors: classification, localization, mechanisms and targets for drugs

1 reference

12 December 2020

Clonidine-induced hypotension: Further evidence for a central interaction with histamine H2 receptor antagonists in the rat☆

1 reference

12 December 2020

Effect of clonidine on Mood pressure and GABAergic mechanisms us spontaneously hypertensive rats

1 reference

12 December 2020

Astrocytes cultured from specific brain regions differ in their expression of adrenergic binding sites.

1 reference

12 December 2020

[3H]idazoxan and some other alpha 2-adrenergic drugs also bind with high affinity to a nonadrenergic site

1 reference

12 December 2020

Central Presynaptic α2-Autoreceptors are Involved in the Blood Pressure-Lowering Effect of Moxonidine

1 reference

12 December 2020

Differences in the central hypotensive actions of alpha-methyldopa and clonidine in the spontaneously hypertensive rat: contribution of neurons arising from the B3 and the C1 areas of the rostral ventrolateral medulla

1 reference

12 December 2020

Evidence for a bioactive clonidine-displacing substance in peripheral tissues and serum

1 reference

12 December 2020

Chemical stimulation of the locus coeruleus: inhibitory effects on hemodynamics and renal sympathetic nerve activity.

1 reference

12 December 2020

Opposite rank order of potency for alpha-2 adrenoceptor agonists on water and solute excretion in the rat: two sites and/or receptors?

1 reference

12 December 2020

Hypotensive action of clonidine analogues correlates with binding affinity at imidazole and not alpha-2-adrenergic receptors in the rostral ventrolateral medulla

1 reference

12 December 2020

Inhibition by ?2-adrenoceptor agonists of the secretion of catecholamines from isolated adrenal medullary cells

1 reference

12 December 2020

Beneficial effect of nifedipine and moxonidine on glomerulosclerosis in spontaneously hypertensive rats. A micromorphometric study

1 reference

12 December 2020

Isolation and partial purification of a clonidine-displacing endogenous brain substance

1 reference

12 December 2020

Maintenance of tonic vasomotor activity by alpha and beta adrenergic mechanisms in medullary cardiovascular centers

1 reference

12 December 2020

The alpha 1- and alpha 2-adrenoceptor involvement in the central cardiovascular action of clonidine in the conscious renal hypertensive cat.

1 reference

12 December 2020

Sympathetic neural control of the kidney in hypertension

1 reference

12 December 2020

An endogenous substance with clonidine-like properties: selective binding to imidazole sites in the ventrolateral medulla

1 reference

12 December 2020

Blockade of the central hypotensive effect of clonidine by alpha-adrenoreceptor and antagonists in rats, rabbits and dogs.

1 reference

12 December 2020

Effect of imidazolines on Na+ transport and intracellular pH in renal proximal tubule cells

1 reference

12 December 2020

An imidazoline-specific mechanism for the hypotensive effect of clonidine: a study with yohimbine and idazoxan

1 reference

12 December 2020

Correlation between the inhibitory effect on catecholaminergic ventrolateral medullary neurons and the hypotension evoked by clonidine: a voltammetric approach

1 reference

12 December 2020

Binding of [3H]p-aminoclonidine to two sites, alpha 2-adrenoceptors and imidazoline binding sites: distribution of imidazoline binding sites in rat brain.

1 reference

12 December 2020

General pharmacology of the novel centrally acting antihypertensive agent moxonidine

1 reference

12 December 2020

Imidazoline receptors: historical perspective

1 reference

12 December 2020

Selectivity of rilmenidine for the nucleus reticularis lateralis, a ventrolateral medullary structure containing imidazoline-preferring receptors

1 reference

12 December 2020

Alpha 2-adrenoceptor subtypes and imidazoline-like binding sites in the rat brain

1 reference

12 December 2020

Brainstem and bulbospinal neurotransmitter systems in the control of blood pressure

1 reference

12 December 2020

Role of alpha 2-adrenergic receptors in the carotid body response to isocapnic hypoxia

1 reference

12 December 2020

Medetomidine stereoisomers delineate two closely related subtypes of idazoxan (imidazoline) I-receptors in the guinea pig

1 reference

12 December 2020

New concepts on the central regulation of blood pressure. Alpha 2-adrenoceptors and "imidazoline receptors".

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12 December 2020

Characterization of alpha 1- and alpha 2-adrenergic receptors.

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12 December 2020

Clonidine-displacing substance is present in peripheral tissues of the rat.

1 reference

12 December 2020

Moxonidine, a centrally acting antihypertensive agent, is a selective ligand for I1-imidazoline sites

1 reference

12 December 2020

Inhibition of respiratory neural discharges by clonidine and 5-hydroxytryptophan

1 reference

12 December 2020

Neuroblastoma-glioma hybrid cells contain clonidine-displacing substance.

1 reference

12 December 2020

Centrally acting antihypertensive agents.

1 reference

12 December 2020

The imidazoline preferring receptor: binding studies in bovine, rat and human brainstem

1 reference

12 December 2020

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1 reference

12 December 2020

Pertussis toxin attenuates clonidine inhibition of catecholamine release in adrenal chromaffin cells

1 reference

12 December 2020

The histaminergic system in the guinea pig central nervous system: An immunocytochemical mapping study using an antiserum against histamine

1 reference

12 December 2020

Alpha 2-adrenergic receptor stimulation mobilizes intracellular Ca2+ in human erythroleukemia cells

1 reference

12 December 2020

Distribution of α2 agonist binding sites in the rat and human central nervous system: Analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents

1 reference

12 December 2020

Clonidine binds to imidazole binding sites as well as alpha 2-adrenoceptors in the ventrolateral medulla

1 reference

12 December 2020

Pharmacokinetic-pharmacodynamic modeling of the effects of clonidine on pain threshold, blood pressure, and salivary flow

1 reference

12 December 2020

Reversal of clonidine-induced hypotension by β-adrenoceptor blocking drugs

1 reference

12 December 2020

Central and peripheral effects of clonidine on the adrenal medullary function in spontaneously hypertensive rats

1 reference

12 December 2020

Rilmenidine: a novel antihypertensive agent

1 reference

12 December 2020

Unique presynaptic alpha 2-receptor selectivity and specificity of the antihypertensive agent moxonidine

1 reference

12 December 2020

Pharmacodynamic action and pharmacokinetics of moxonidine after single oral administration in hypertension patients

1 reference

12 December 2020

Fitting curves to data using nonlinear regression: a practical and nonmathematical review

1 reference

12 December 2020

Clonidine hypotension: lack of effect of bilateral lesions of the nucleus solitary tract in anaesthetized cats

1 reference

12 December 2020

Stimulation of alpha 2-adrenergic receptors in nucleus tractus solitarius is required for the baroreceptor reflex.

1 reference

12 December 2020

Reversal by ethanol of the hypotensive effect of clonidine in conscious spontaneously hypertensive rats

1 reference

12 December 2020

Binding of [3H]-p-aminoclonidine to α2adrenoceptor states plus a non-adrenergic site on human platelet plasma membranes

1 reference

12 December 2020

Imidazoline-guanidinium receptive site in renal proximal tubule: asymmetric distribution, regulation by cations and interaction with an endogenous clonidine displacing substance

1 reference

12 December 2020

Are there multiple imidazoline binding sites?

1 reference

12 December 2020

Guanfacine: a second generation alpha 2-adrenergic blocker

1 reference

12 December 2020

Characterization of alpha-adrenoceptors participating in the central hypotensive and sedative effects of clonidine using yohimbine, rauwolscine and corynanthine

1 reference

12 December 2020

Alpha 2-adrenoceptors do not regulate catecholamine secretion by bovine adrenal medullary cells: a study with clonidine

1 reference

12 December 2020

Rilmenidine (S 3341) and the sympathoadrenal system: adrenoreceptors, plasma and adrenal catecholamines in dogs

1 reference

12 December 2020

Central cardiovascular effects of alpha adrenergic drugs: differences between catecholamines and imidazolines

1 reference

12 December 2020

The effect of clonidine on centrally and peripherally evoked submaxillary salivation

1 reference

12 December 2020

Quantitative distribution of muscarinic receptors and choline acetyltransferase in rat medulla: examination of transmitter-receptor mismatch

1 reference

12 December 2020

Keeping an eye on the I site: imidazoline-preferring receptors

1 reference

12 December 2020

Importance of Central Noradrenergic and Serotonergic Pathways in the Cardiovascular Actions of Rilmenidine and Clonidine

1 reference

12 December 2020

Clonidine-specific antibodies as models for imidazole and alpha 2-adrenergic receptor binding sites: implications for the structure of clonidine-displacing substance

1 reference

12 December 2020

Central α-adrenergic systems as targets for hypotensive drugs

1 reference

12 December 2020

Role of imidazole receptors in the vasodepressor response to clonidine analogs in the rostral ventrolateral medulla.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00877082

1 reference

9 February 2018

1 reference

9 February 2018