(Q48168758)

9 February 2018

title

Molecular genetics of the aip gene in familial pituitary tumorigenesis (English)

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9 February 2018

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3

Márta Korbonits

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author name string

Asil Tahir

series ordinal

1

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9 February 2018

Harvinder S Chahal

series ordinal

2

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9 February 2018

Márta Korbonits

series ordinal

3

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9 February 2018

publication date

1 January 2010

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9 February 2018

Progress in Brain Research

published in

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9 February 2018

volume

182

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9 February 2018

page(s)

229-253

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9 February 2018

Rare germline mutations in cyclin-dependent kinase inhibitor genes in multiple endocrine neoplasia type 1 and related states

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Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2

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Phenotype and phenocopy: the relationship between genotype and clinical phenotype in a single large family with multiple endocrine neoplasia type 1 (MEN 1)

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The dependence receptor Ret induces apoptosis in somatotrophs through a Pit-1/p53 pathway, preventing tumor growth.

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The complex of myxomas, spotty pigmentation, and endocrine overactivity

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Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo

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7 January 2021

Characterization of the Ah receptor-associated protein, ARA9

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7 January 2021

Germline inactivating mutations of the aryl hydrocarbon receptor-interacting protein gene in a large cohort of sporadic acromegaly: mutations are found in a subset of young patients with macroadenomas

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7 January 2021

Clinical, genetic and molecular characterization of patients with familial isolated pituitary adenomas (FIPA).

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Sporadic pituitary tumours: from epidemiology to use of databases

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Mutation and expression analysis of the p27/kip1 gene in corticotrophin-secreting tumours

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7 January 2021

Clinical characterization of familial isolated pituitary adenomas.

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7 January 2021

High prevalence of pituitary adenomas: a cross-sectional study in the province of Liege, Belgium

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7 January 2021

Aryl hydrocarbon receptor-interacting protein gene mutations in familial isolated pituitary adenomas: analysis in 73 families.

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7 January 2021

Acromegaly and gigantism in the medical literature. Case descriptions in the era before and the early years after the initial publication of Pierre Marie (1886)

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7 January 2021

Phosphodiesterase 2A forms a complex with the co-chaperone XAP2 and regulates nuclear translocation of the aryl hydrocarbon receptor

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7 January 2021

Wnt pathway inhibitors are strongly down-regulated in pituitary tumors

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7 January 2021

The prevalence of pituitary adenomas: a systematic review

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7 January 2021

Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis

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7 January 2021

The co-chaperone XAP2 is required for activation of hypothalamic thyrotropin-releasing hormone transcription in vivo

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7 January 2021

Isolated familial somatotropinomas: establishment of linkage to chromosome 11q13.1-11q13.3 and evidence for a potential second locus at chromosome 2p16-12

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Aryl hydrocarbon receptor interacting protein(AIP) gene mutation analysis in children and adolescents with sporadic pituitary adenomas

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Germline CDKN1B/p27Kip1 mutation in multiple endocrine neoplasia

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Clinical features of multiple endocrine neoplasia type 1 (MEN1) phenocopy without germline MEN1 gene mutations: analysis of 20 Japanese sporadic cases with MEN1.

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Imprinting of the G(s)alpha gene GNAS1 in the pathogenesis of acromegaly

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7 January 2021

The expression of AIP-related molecules in elucidation of cellular pathways in pituitary adenomas

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7 January 2021

Clonal origin of pituitary adenomas

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7 January 2021

The impact of aryl hydrocarbon receptor signaling on matrix metabolism: implications for development and disease

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7 January 2021

Epidemiology of acromegaly

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7 January 2021

The aryl hydrocarbon (Ah) receptor transcriptional regulator hepatitis B virus X-associated protein 2 antagonizes p23 binding to Ah receptor-Hsp90 complexes and is dispensable for receptor function

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7 January 2021

Clinical and molecular genetics of acromegaly: MEN1, Carney complex, McCune-Albright syndrome, familial acromegaly and genetic defects in sporadic tumors

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7 January 2021

Assessment of p27 (cyclin-dependent kinase inhibitor 1B) and aryl hydrocarbon receptor-interacting protein (AIP) genes in multiple endocrine neoplasia (MEN1) syndrome patients without any detectable MEN1 gene mutations

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7 January 2021

Characterization of aryl hydrocarbon receptor interacting protein (AIP) mutations in familial isolated pituitary adenoma families

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7 January 2021

Expression of aryl hydrocarbon receptor (AHR) and AHR-interacting protein in pituitary adenomas: pathological and clinical implications.

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7 January 2021

Aggressive pituitary adenomas occurring in young patients in a large Polynesian kindred with a germline R271W mutation in the AIP gene.

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7 January 2021

Regulation of survivin stability by the aryl hydrocarbon receptor-interacting protein.

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7 January 2021

Epstein-Barr virus encoded nuclear protein EBNA-3 binds XAP-2, a protein associated with Hepatitis B virus X antigen

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7 January 2021

The immunophilin-like protein XAP2 regulates ubiquitination and subcellular localization of the dioxin receptor

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7 January 2021

Two distinct regions of the immunophilin-like protein XAP2 regulate dioxin receptor function and interaction with hsp90

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7 January 2021

Genome-wide scan identifies novel modifier loci of acromegalic phenotypes for isolated familial somatotropinoma

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Frequent loss of the CDKN2C (p18INK4c) gene product in pituitary adenomas.

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex.

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7 January 2021

Mutation and cancer: statistical study of retinoblastoma

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7 January 2021

The EBNA-3 gene family proteins disrupt the G2/M checkpoint

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7 January 2021

XAP2, a novel hepatitis B virus X-associated protein that inhibits X transactivation

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7 January 2021

ARA9 modifies agonist signaling through an increase in cytosolic aryl hydrocarbon receptor

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7 January 2021

XAP2 inhibits glucocorticoid receptor activity in mammalian cells

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7 January 2021

GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours.

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7 January 2021

The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas.

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

A meiotic recombination in a new isolated familial somatotropinoma kindred

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7 January 2021

Multiple endocrine neoplasia type 1

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7 January 2021

Aromatic hydrocarbon receptor-driven Bax gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals

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7 January 2021

FAMILIAL ACROMEGALY: STUDIES IN THREE FAMILIES

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7 January 2021

Characterization of the AhR-hsp90-XAP2 core complex and the role of the immunophilin-related protein XAP2 in AhR stabilization

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7 January 2021

Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity

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7 January 2021

The epidemiology of endocrine tumours

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7 January 2021

Expression of pituitary tumour-derived, N-terminally truncated isoform of fibroblast growth factor receptor 4 (ptd-FGFR4) correlates with tumour invasiveness but not with G-protein alpha subunit (gsp) mutation in human GH-secreting pituitary adenoma

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7 January 2021

G-protein signalling negatively regulates the stability of aryl hydrocarbon receptor

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7 January 2021

Variable pathological and clinical features of a large Brazilian family harboring a mutation in the aryl hydrocarbon receptor-interacting protein gene

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7 January 2021

Aryl hydrocarbon receptor activation by cAMP vs. dioxin: divergent signaling pathways

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7 January 2021

Dioxin receptor is a ligand-dependent E3 ubiquitin ligase

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7 January 2021

Germline mutations in theCDKN1Bgene encoding p27Kip1are a rare cause of multiple endocrine neoplasia type 1

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7 January 2021

The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27Kip1 mutations

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7 January 2021

Genetic and histologic studies of somatomammotropic pituitary tumors in patients with the "complex of spotty skin pigmentation, myxomas, endocrine overactivity and schwannomas" (Carney complex).

1 reference

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7 January 2021

Aryl hydrocarbon receptor facilitates DNA strand breaks and 8-oxo-2'-deoxyguanosine formation by the aldo-keto reductase product benzo[a]pyrene-7,8-dione

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7 January 2021

Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

1 reference

7 January 2021

Subcellular localization of the aryl hydrocarbon receptor is modulated by the immunophilin homolog hepatitis B virus X-associated protein 2

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

The hsp90 Co-chaperone XAP2 alters importin beta recognition of the bipartite nuclear localization signal of the Ah receptor and represses transcriptional activity

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7 January 2021

The role of chaperone proteins in the aryl hydrocarbon receptor core complex

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7 January 2021

Redefining the role of the endogenous XAP2 and C-terminal hsp70-interacting protein on the endogenous Ah receptors expressed in mouse and rat cell lines.

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7 January 2021

No evidence of somatic aryl hydrocarbon receptor interacting protein mutations in sporadic endocrine neoplasia

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Divergent roles of hepatitis B virus X-associated protein 2 (XAP2) in human versus mouse Ah receptor complexes

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Inactivation of the p16 gene in human pituitary nonfunctioning tumors by hypermethylation is more common in null cell adenomas

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7 January 2021

Familial Cushing Disease

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7 January 2021

High prevalence of biochemical acromegaly in primary care patients with elevated IGF-1 levels

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Preferential loss of Death Associated Protein kinase expression in invasive pituitary tumours is associated with either CpG island methylation or homozygous deletion

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Tumor deletion mapping on chromosome 11q13 in eight families with isolated familial somatotropinoma and in 15 sporadic somatotropinomas

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7 January 2021

Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions

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7 January 2021

Human tumors associated with Carney complex and germline PRKAR1A mutations: a protein kinase A disease!

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7 January 2021

Carney complex, a familial multiple neoplasia and lentiginosis syndrome. Analysis of 11 kindreds and linkage to the short arm of chromosome 2.

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7 January 2021

Evidence that peroxisome proliferator-activated receptor alpha is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2

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7 January 2021

P53 gene mutations in pituitary carcinomas

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7 January 2021

Multiple Endocrine Neoplasia--Syndromes of the Twentieth Century

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7 January 2021

Octreotide, a somatostatin analogue, mediates its antiproliferative action in pituitary tumor cells by altering phosphatidylinositol 3-kinase signaling and inducing Zac1 expression

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Familial pituitary adenomas.

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Germline mutation in the aryl hydrocarbon receptor interacting protein gene in familial somatotropinoma

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7 January 2021

T Cell-Specific Disruption of Arylhydrocarbon Receptor Nuclear Translocator (Arnt) Gene Causes Resistance to 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Induced Thymic Involution

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

The tyrosine kinase receptor RET interacts in vivo with aryl hydrocarbon receptor-interacting protein to alter survivin availability

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Pituitary adenoma predisposition caused by germline mutations in the AIP gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Patent ductus venosus and dioxin resistance in mice harboring a hypomorphic Arnt allele

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Genetic aspects of adenomatosis of endocrine glands

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

G(12)/G(13)-mediated signalling in mammalian physiology and disease

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

The PPAR alpha-humanized mouse: a model to investigate species differences in liver toxicity mediated by PPAR alpha

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

AIP is a mitochondrial import mediator that binds to both import receptor Tom20 and preproteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Pituitary Tumor Transforming Gene (PTTG) Expression in Pituitary Adenomas

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Loss of expression of GADD45 gamma, a growth inhibitory gene, in human pituitary adenomas: implications for tumorigenesis

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https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

A Pituitary-Derived MEG3 Isoform Functions as a Growth Suppressor in Tumor Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2810%2982010-2

7 January 2021

10.1016/S0079-6123(10)82010-2

Identifiers

DOI

1 reference

9 February 2018

1 reference

9 February 2018