(Q48173324)

9 February 2018

title

Topoisomerase I-mediated cleavage at unrepaired ribonucleotides generates DNA double-strand breaks (English)

1 reference

9 February 2018

5

Yves Pommier

1 reference

9 February 2018

Shar-Yin N Huang

1

1 reference

9 February 2018

Jessica S Williams

series ordinal

2

1 reference

9 February 2018

Mercedes E Arana

series ordinal

3

1 reference

9 February 2018

Thomas A Kunkel

series ordinal

4

1 reference

9 February 2018

language of work or name

English

0 references

publication date

8 December 2016

1 reference

9 February 2018

published in

The EMBO Journal

1 reference

9 February 2018

volume

36

1 reference

9 February 2018

issue

3

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9 February 2018

page(s)

361-373

1 reference

9 February 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5286372/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs

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22 May 2018

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Two distinct mechanisms of Topoisomerase 1-dependent mutagenesis in yeast

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Transcriptional responses to loss of RNase H2 in Saccharomyces cerevisiae.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

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22 May 2018

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22 May 2018

1 reference

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Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.

22 May 2018

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Solution Structure of the Dickerson DNA Dodecamer Containing a Single Ribonucleotide

22 May 2018

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RNase H and postreplication repair protect cells from ribonucleotides incorporated in DNA

22 May 2018

1 reference

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Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype

22 May 2018

1 reference

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RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability

22 May 2018

1 reference

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Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase ε.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Topoisomerase 1 provokes the formation of short deletions in repeated sequences upon high transcription in Saccharomyces cerevisiae

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Role for topoisomerase 1 in transcription-associated mutagenesis in yeast

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Genome instability due to ribonucleotide incorporation into DNA.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Highly mutagenic and severely imbalanced dNTP pools can escape detection by the S-phase checkpoint

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Ribonuclease H: the enzymes in eukaryotes

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Division of labor at the eukaryotic replication fork

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Recombination proteins in yeast

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

In vivo assembly and disassembly of Rad51 and Rad52 complexes during double-strand break repair

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Excision of misincorporated ribonucleotides in DNA by RNase H (type 2) and FEN-1 in cell-free extracts

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

In vivo consequences of putative active site mutations in yeast DNA polymerases alpha, epsilon, delta, and zeta

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Rad52 forms DNA repair and recombination centers during S phase

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Mutator phenotypes conferred by MLH1 overexpression and by heterozygosity for mlh1 mutations.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Site-specific ribonuclease activity of eukaryotic DNA topoisomerase I.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Analysis of the biased distribution of topoisomerase I break sites on replicating simian virus 40 DNA.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Physiological concentrations of purines and pyrimidines

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

A single 2'-hydroxyl group converts B-DNA to A-DNA. Crystal structure of the DNA-RNA chimeric decamer duplex d(CCGGC)r(G)d(CCGG) with a novel intermolecular G-C base-paired quadruplet

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Mapping in vivo topoisomerase I sites on simian virus 40 DNA: asymmetric distribution of sites on replicating molecules

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

DNA cleavage assay for the identification of topoisomerase I inhibitors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

RNA intrusions change DNA elastic properties and structure

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5286372

Trapping of mammalian topoisomerase I and recombinations induced by damaged DNA containing nicks or gaps. Importance of DNA end phosphorylation and camptothecin effects

2 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27932446

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27932446

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.15252/EMBJ.201592426

1 reference

9 February 2018

PMC publication ID

5286372

1 reference

9 February 2018

PubMed publication ID

27932446

1 reference

9 February 2018