(Q48215990)

9 February 2018

title

A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production (English)

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9 February 2018

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21

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Mads Gyrd-Hansen

22

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9 February 2018

Michael W Parker

23

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9 February 2018

Elizabeth L. Hartland

24

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9 February 2018

Phillip P. Sharp

Phillip P Sharp

15

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Andrew M Lew

Andrew M Lew

25

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John Silke

John Silke

28

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Ueli Nachbur

Ueli Nachbur

1

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Yifan Zhan

Yifan Zhan

4

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Catherine L Kennedy

Catherine L Kennedy

19

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Jessica K Holien

11

Jessica K Holien

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9 February 2018

author name string

Che A Stafford

2

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9 February 2018

Aleksandra Bankovacki

3

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9 February 2018

Lisa M Lindqvist

5

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9 February 2018

Berthe K Fiil

6

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Yelena Khakham

7

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9 February 2018

Hyun-Ja Ko

8

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Jarrod J Sandow

9

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9 February 2018

Hendrik Falk

10

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9 February 2018

Diep Chau

12

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9 February 2018

Joanne Hildebrand

13

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James E Vince

14

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9 February 2018

Andrew I Webb

16

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9 February 2018

Katherine A Jackman

17

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9 February 2018

Sabrina Mühlen

18

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9 February 2018

Kym N Lowes

20

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David C S Huang

26

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9 February 2018

Guillaume Lessene

27

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9 February 2018

language of work or name

English

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publication date

17 March 2015

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9 February 2018

published in

Nature Communications

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9 February 2018

volume

6

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9 February 2018

page(s)

6442

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9 February 2018

https://scigraph.springernature.com/pub.10.1038/ncomms7442

exact match

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cites work

An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

NOD2 contributes to cutaneous defense against Staphylococcus aureus through alpha-toxin-dependent innate immune activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

NOD2/CARD15 disease associations other than Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Essential role of Rip2 in the modulation of innate and adaptive immunity triggered by Nod1 and Nod2 ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

OTULIN restricts Met1-linked ubiquitination to control innate immune signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Participation of Rip2 in lipopolysaccharide signaling is independent of its kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

The kinase activity of Rip2 determines its stability and consequently Nod1- and Nod2-mediated immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Identification of a regulatory autophosphorylation site in the serine-threonine kinase RIP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Inhibition of RIP2/RIck/CARDIAK activity by pyridinyl imidazole inhibitors of p38 MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Structural basis of RIP1 inhibition by necrostatins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Main-chain bond lengths and bond angles in protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Receptor-interacting protein (RIP) kinase family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

The RIP kinases: crucial integrators of cellular stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

RIP1, a kinase on the crossroads of a cell's decision to live or die

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Identifying the proteins to which small-molecule probes and drugs bind in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

XIAP mediates NOD signaling via interaction with RIP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Comparative protein modelling by satisfaction of spatial restraints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Combination of FASP and StageTip-based fractionation allows in-depth analysis of the hippocampal membrane proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Control of dual-specificity phosphatase-1 expression in activated macrophages by IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Inflammatory monocytes facilitate adaptive CD4 T cell responses during respiratory fungal infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Transplantation of autoimmune regulator-encoding bone marrow cells delays the onset of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7442

Is BID required for NOD signalling?

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25778803

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS7442

1 reference

9 February 2018

Dimensions Publication ID

ADS bibcode

2015NatCo...6.6442N

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1016434672

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1 reference

9 February 2018