(Q48231010)

English

Brain-derived neurotrophic factor mediates the anti-apoptotic effect of NMDA in cerebellar granule neurons: signal transduction cascades and site of ethanol action.

scientific article published in May 1999

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scholarly article

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Europe PubMed Central

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4 December 2019

Brain-derived neurotrophic factor mediates the anti-apoptotic effect of NMDA in cerebellar granule neurons: signal transduction cascades and site of ethanol action (English)

1 reference

Europe PubMed Central

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4 December 2019

apoptotic process

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1

1 reference

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4 December 2019

author name string

L Ghoda

2

1 reference

Europe PubMed Central

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4 December 2019

P L Hoffman

3

1 reference

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4 December 2019

language of work or name

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publication date

1 May 1999

1 reference

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4 December 2019

Journal of Neuroscience

1 reference

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4 December 2019

19

1 reference

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4 December 2019

9

1 reference

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4 December 2019

3277-3286

1 reference

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4 December 2019

Glutamate-induced neurotoxicity is increased in cerebellar granule cells exposed chronically to ethanol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depolarization or glutamate receptor activation blocks apoptotic cell death of cultured cerebellar granule neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling pathways and survival effects of BDNF and NT-3 on cultured cerebellar granule cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A DEVD-inhibited caspase other than CPP32 is involved in the commitment of cerebellar granule neurons to apoptosis induced by K+ deprivation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol induces apoptosis in cerebellar granule neurons by inhibiting insulin-like growth factor 1 signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA-stimulated expression of BDNF mRNA in cultured cerebellar granule neurones.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposite effect of protein synthesis inhibitors on potassium deficiency-induced apoptotic cell death in immature and mature neuronal cultures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional and subunit specific changes in NMDA receptor mRNA and immunoreactivity in mouse brain following chronic ethanol ingestion

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of caspase-3 and apoptosis in cerebellar granule cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of neuronal migration by NMDA receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mitogen-activated protein kinase and p70S6 kinase is not correlated with cerebellar granule cell survival.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pituitary adenylate cyclase-activating polypeptide stimulates both c-fos gene expression and cell survival in rat cerebellar granule neurons through activation of the protein kinase A pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pituitary adenylate cyclase-activating polypeptide (PACAP-38) protects cerebellar granule neurons from apoptosis by activating the mitogen-activated protein kinase (MAP kinase) pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin receptor substrate (IRS)-1 and IRS-2 are tyrosine-phosphorylated and associated with phosphatidylinositol 3-kinase in response to brain-derived neurotrophic factor in cultured cerebral cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of cell death mediated by membrane depolarization different from that by exogenous BDNF in cultured mouse cerebellar granule cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-methyl-D-aspartate receptors and ethanol: inhibition of calcium flux and cyclic GMP production

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitatory synaptic transmission in neostriatal neurons: regulation by cyclic AMP-dependent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of BDNF and NT-3 mRNA levels in primary cultures of rat cerebellar neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic AMP and pituitary adenylate cyclase-activating polypeptide (PACAP) prevent programmed cell death of cultured rat cerebellar granule cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor suppresses programmed death of cerebellar granule cells through a posttranslational mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of phosphatidylinositol-3 kinase by nerve growth factor involves indirect coupling of the trk proto-oncogene with src homology 2 domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pituitary adenylate cyclase activating polypeptide prevents apoptosis in cultured cerebellar granule neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of G Proteins Bidirectionally Affects Apoptosis of Cultured Cerebellar Granule Neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity-dependent release of brain-derived neurotrophic factor underlies the neuroprotective effect of N-methyl-D-aspartate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol promotes apoptosis in cerebellar granule cells by inhibiting the trophic effect of NMDA

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic exposure of cerebellar granule cells to ethanol results in increased N-methyl-D-aspartate receptor function

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophins protect cultured cerebellar granule neurons against the early phase of cell death by a two-component mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A branched signaling pathway for nerve growth factor is revealed by Src-, Ras-, and Raf-mediated gene inductions

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed increase of Ca2+ influx elicited by glutamate: role in neuronal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for BDNF in activity-dependent survival of cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of phosphatidylinositol-3 kinase in prevention of low K(+)-induced apoptosis of cerebellar granule neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downstream signalling events regulated by phosphatidylinositol 3-kinase activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and expression of a rat brain interleukin-1beta-converting enzyme (ICE)-related protease (IRP) and its possible role in apoptosis of cultured cerebellar granule neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential neuronal loss following early postnatal alcohol exposure.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promotion of granule cell survival by high K+ or excitatory amino acid treatment and Ca2+/calmodulin-dependent protein kinase activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of insulin-like growth factor analogues on survival of cultured cerebral cortex and cerebellar granule neurones.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and cellular aspects of the insulin-like growth factor I receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The activation of phosphatidylinositol 3-kinase by Ras

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal cerebellar development and foliation in BDNF-/- mice reveals a role for neurotrophins in CNS patterning.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-methyl-D-aspartate promotes the survival of cerebellar granule cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10212287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.19-09-03277.1999

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10212287%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10212287%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10212287%20AND%20SRC:MED&resulttype=core&format=json

4 December 2019

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