(Q48239282)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832990%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

title

Identification of the rate-determining process in the hepatic clearance of atorvastatin in a clinical cassette microdosing study (English)

1 reference

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10 February 2020

4

1 reference

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10 February 2020

author name string

K Maeda

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832990%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Y Ikeda

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832990%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

T Fujita

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832990%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Y Azuma

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832990%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Y Haruyama

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832990%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

N Yamane

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832990%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Y Kumagai

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832990%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Y Sugiyama

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832990%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

language of work or name

English

0 references

publication date

10 August 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832990%20AND%20SRC:MED&resulttype=core&format=json

Clinical Pharmacology & Therapeutics

10 February 2020

published in

1 reference

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10 February 2020

volume

90

1 reference

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10 February 2020

page(s)

575-581

1 reference

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10 February 2020

issue

4

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Transporters as a determinant of drug clearance and tissue distribution

10 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

In vitro-in vivo extrapolation of transporter-mediated clearance in the liver and kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Investigation of the rate-determining process in the hepatic elimination of HMG-CoA reductase inhibitors in rats and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Appropriate phenotyping procedures for drug metabolizing enzymes and transporters in humans and their simultaneous use in the "cocktail" approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Membrane transporters in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Clinical Pharmacokinetics of Atorvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

effect of OATP1B transporter inhibition on the pharmacokinetics of atorvastatin in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

The quantitative prediction of CYP-mediated drug interaction by physiologically based pharmacokinetic modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Drug-drug interaction between pitavastatin and various drugs via OATP1B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Investigation of the inhibitory effects of various drugs on the hepatic uptake of fexofenadine in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Itraconazole alters the pharmacokinetics of atorvastatin to a greater extent than either cerivastatin or pravastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Effects of a concomitant single oral dose of rifampicin on the pharmacokinetics of pravastatin in a two-phase, randomized, single-blind, placebo-controlled, crossover study in healthy Chinese male subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Molecular characterization and inhibition of amanitin uptake into human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Metabolism of repaglinide by CYP2C8 and CYP3A4 in vitro: effect of fibrates and rifampicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Multiple transporters affect the disposition of atorvastatin and its two active hydroxy metabolites: application of in vitro and ex situ systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Metabolism and transporter-mediated drug-drug interactions of the endothelin-A receptor antagonist CI-1034.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Functional characterization of SLCO1B1 (OATP-C) variants, SLCO1B1*5, SLCO1B1*15 and SLCO1B1*15+C1007G, by using transient expression systems of HeLa and HEK293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Analysis of nonlinear and nonsteady state hepatic extraction with the dispersion model using the finite difference method.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Different Effects of SLCO1B1 Polymorphism on the Pharmacokinetics of Atorvastatin and Rosuvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

Effect of itraconazole on the pharmacokinetics of atorvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

inferred from DOI database lookup

7 January 2021

based on heuristic

Physiological parameters in laboratory animals and humans

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

inferred from DOI database lookup

7 January 2021

based on heuristic

Binding of rifampicin by human plasma proteins.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.142

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/CLPT.2011.142

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832990%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference