(Q48240221)

http://europepmc.org/abstract/PMC/5768770

9 February 2018

title

Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing. (English)

1 reference

http://europepmc.org/abstract/PMC/5768770

9 February 2018

1 reference

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Axel M Hillmer

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Weiwei Zhai

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Zhang, Tong

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Chee Keong Toh

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Bing Lim

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Rahul Nahar

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Angela Takano

4

1 reference

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4 June 2020

Alexis J Khng

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Yin Yeng Lee

6

1 reference

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4 June 2020

Xingliang Liu

7

1 reference

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4 June 2020

Chong Hee Lim

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Tina P T Koh

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Zaw Win Aung

10

1 reference

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4 June 2020

Tony Kiat Hon Lim

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Lavanya Veeravalli

12

1 reference

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4 June 2020

Ju Yuan

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Audrey S M Teo

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Cheryl X Chan

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Huay Mei Poh

16

1 reference

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4 June 2020

Ivan M L Chua

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Audrey Ann Liew

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Dawn Ping Xi Lau

19

1 reference

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4 June 2020

Xue Lin Kwang

20

1 reference

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4 June 2020

Wan-Teck Lim

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Eng-Huat Tan

25

1 reference

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4 June 2020

Daniel S W Tan

27

1 reference

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4 June 2020

language of work or name

English

0 references

publication date

15 January 2018

1 reference

http://europepmc.org/abstract/PMC/5768770

9 February 2018

published in

Nature Communications

1 reference

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4 June 2020

volume

9

1 reference

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4 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

216

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

4 June 2020

copyright license

start time

15 January 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/s41467-017-02584-z

0 references

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22 May 2018

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High-throughput Phenotyping of Lung Cancer Somatic Mutations

22 May 2018

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Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

22 May 2018

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Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells

22 May 2018

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Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition

22 May 2018

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Identification of neutral tumor evolution across cancer types.

22 May 2018

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Clock-like mutational processes in human somatic cells

22 May 2018

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Impact of Smoking and Brain Metastasis on Outcomes of Advanced EGFR Mutation Lung Adenocarcinoma Patients Treated with First Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

22 May 2018

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Impact of metabolic heterogeneity on tumor growth, invasion, and treatment outcomes.

22 May 2018

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Clonal status of actionable driver events and the timing of mutational processes in cancer evolution

22 May 2018

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Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

22 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

β-catenin contributes to lung tumor development induced by EGFR mutations

22 May 2018

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Tumour heterogeneity and the evolution of polyclonal drug resistance

22 May 2018

1 reference

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Comprehensive molecular profiling of lung adenocarcinoma

22 May 2018

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Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity

22 May 2018

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Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs

22 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Genomic profiling of hepatocellular adenomas reveals recurrent FRK-activating mutations and the mechanisms of malignant transformation

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

PyClone: statistical inference of clonal population structure in cancer.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Discovery and saturation analysis of cancer genes across 21 tumour types

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Genomic and transcriptional alterations in lung adenocarcinoma in relation to EGFR and KRAS mutation status

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

A genomics-based classification of human lung tumors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Mutational landscape and significance across 12 major cancer types

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Pan-cancer patterns of somatic copy number alteration

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Signatures of mutational processes in human cancer

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Comprehensive molecular characterization of clear cell renal cell carcinoma

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Mutational heterogeneity in cancer and the search for new cancer-associated genes

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

EMu: probabilistic inference of mutational processes and their localization in the cancer genome

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Evolution and impact of subclonal mutations in chronic lymphocytic leukemia

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Disruption of PH-kinase domain interactions leads to oncogenic activation of AKT in human cancers

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Why imatinib remains an exception of cancer research

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Genomic landscape of non-small cell lung cancer in smokers and never-smokers

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

HER2 amplification: a potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFRT790M mutation

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Strelka: accurate somatic small-variant calling from sequenced tumor-normal sample pairs

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Absolute quantification of somatic DNA alterations in human cancer

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Genomic profiles specific to patient ethnicity in lung adenocarcinoma

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

A framework for variation discovery and genotyping using next-generation DNA sequencing data

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Allele-specific copy number analysis of tumors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

The landscape of somatic copy-number alteration across human cancers

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Fast and accurate short read alignment with Burrows-Wheeler transform

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Somatic mutations affect key pathways in lung adenocarcinoma

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Characterizing the cancer genome in lung adenocarcinoma

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

A census of human cancer genes

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

APE: Analyses of Phylogenetics and Evolution in R language

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Dynamics of Tumor Heterogeneity Derived from Clonal Karyotypic Evolution.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Genomic and transcriptional alterations in lung adenocarcinoma in relation to smoking history

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5768770

Mutations of the p53 Gene as a Predictor of Poor Prognosis in Patients With Non-Small-Cell Lung Cancer

14 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41467-017-02584-Z

10.1038/S41467-017-02584-Z

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29335443%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

PubMed publication ID

29335443

1 reference