(Q48241008)

9 February 2018

title

Improved reversal learning and altered fear conditioning in transgenic mice with regionally restricted p25 expression. (English)

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9 February 2018

author

Florian Plattner

2

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9 February 2018

author name string

Marco Angelo

1

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9 February 2018

Elaine E Irvine

3

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9 February 2018

K Peter Giese

4

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9 February 2018

language of work or name

English

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publication date

1 July 2003

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9 February 2018

European Journal of Neuroscience

published in

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9 February 2018

volume

18

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9 February 2018

page(s)

423-431

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9 February 2018

issue

2

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9 February 2018

Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5

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Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments

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Learning and memory in transgenic mice modeling Alzheimer's disease

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Axonopathy, tau abnormalities, and dyskinesia, but no neurofibrillary tangles in p25-transgenic mice.

21 January 2018

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Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegeneration

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Overexpression of hAPPswe impairs rewarded alternation and contextual fear conditioning in a transgenic mouse model of Alzheimer's disease

21 January 2018

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Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment.

21 January 2018

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Central cholinergic systems and cognition

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Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water maze.

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Neurofilament protein synthesis and phosphorylation

21 January 2018

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Cleavage of the cyclin-dependent kinase 5 activator p35 to p25 does not induce tau hyperphosphorylation

21 January 2018

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Effect of excitotoxic lesions of rat medial prefrontal cortex on spatial memory

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Neurotoxicity induces cleavage of p35 to p25 by calpain

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Regulation of NMDA receptors by cyclin-dependent kinase-5

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CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP

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Assessment of learning by the Morris water task and fear conditioning in inbred mouse strains and F1 hybrids: implications of genetic background for single gene mutations and quantitative trait loci analyses.

21 January 2018

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Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

21 January 2018

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Spatial memory dissociations in mice lacking GluR1.

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Alzheimer's disease is a synaptic failure

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Involvement of cyclin dependent kinase5 activator p25 on tau phosphorylation in mouse brain

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A survey of Cdk5 activator p35 and p25 levels in Alzheimer's disease brains

21 January 2018

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Hyperphosphorylation and accumulation of neurofilament proteins in Alzheimer disease brain and in okadaic acid-treated SY5Y cells

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Neurobiology: p25 protein in neurodegeneration

21 January 2018

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10.1046/J.1460-9568.2003.02746.X

21 January 2018

Identifiers

DOI

1 reference

9 February 2018

PubMed ID

12887424

1 reference

9 February 2018