(Q48259430)

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Leptolyngbyolides, Cytotoxic Macrolides from the Marine Cyanobacterium Leptolyngbya sp.: Isolation, Biological Activity, and Catalytic Asymmetric Total Synthesis.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422340%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Leptolyngbyolides, Cytotoxic Macrolides from the Marine Cyanobacterium Leptolyngbya sp.: Isolation, Biological Activity, and Catalytic Asymmetric Total Synthesis (English)

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18 March 2020

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(1R,3S,5E,7E,11R,12S,13R,15S,16R,17S,19S)-3-hydroxy-11-[(2S,3S,4S)-3-hydroxy-6-[(2S,4R,6S)-4-methoxy-6-methyloxan-2-yl]-4-methylhexan-2-yl]-16-(hydroxymethyl)-13,15,17-trimethoxy-6,12-dimethyl-10,23-dioxabicyclo[17.3.1]tricosa-5,7,21-trien-9-one

1 reference

(1R,3S,5E,7E,11R,12S,13R,15S,16R,17S,19S)-3-hydroxy-11-[(2S,3S,4S)-3-hydroxy-6-[(2S,4R,6S)-4-methoxy-6-methyloxan-2-yl]-4-methylhexan-2-yl]-13,15,17-trimethoxy-6,12,16-trimethyl-10,23-dioxabicyclo[17.3.1]tricosa-5,7,21-trien-9-one

1 reference

QRNJWCXUTNJCFF-HIUFMXKQSA-N

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WQAGYQWCNZVPBH-NMCKKDOKSA-N

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WQAGYQWCNZVPBH-WSDAVYQWSA-N

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QRNJWCXUTNJCFF-LCMRYDMKSA-N

1 reference

1 reference

Kiyotake Suenaga

7

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18 March 2020

Tomoyuki Kimura

4

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18 March 2020

Takumi Watanabe

6

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18 March 2020

Masakatsu Shibasaki

8

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18 March 2020

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Jin Cui

1

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18 March 2020

Maho Morita

2

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18 March 2020

Osamu Ohno

3

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18 March 2020

Toshiaki Teruya

5

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18 March 2020

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31 May 2017

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18 March 2020

Chemistry—A European Journal

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18 March 2020

23

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18 March 2020

35

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18 March 2020

8500-8509

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18 March 2020

Marine natural products. XXIII. Three new cytotoxic dimeric macrolides, swinholides B and C and isoswinholide A, congeners of swinholide A, from the Okinawan marine sponge Theonella swinhoei

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701183

21 January 2018

Swinholide A is a microfilament disrupting marine toxin that stabilizes actin dimers and severs actin filaments

1 reference

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21 January 2018

Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms

1 reference

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Seaweed resistance to microbial attack: a targeted chemical defense against marine fungi

1 reference

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Two Molecules of Lobophorolide Cooperate to Stabilize an Actin Dimer Using Both Their “Ring” and “Tail” Region

1 reference

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21 January 2018

Human ICE/CED-3 protease nomenclature

1 reference

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1 reference

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21 January 2018

Actin, a central player in cell shape and movement

1 reference

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Trisoxazole macrolide toxins mimic the binding of actin-capping proteins to actin

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Structure basis for antitumor effect of aplyronine a.

1 reference

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21 January 2018

Structures of microfilament destabilizing toxins bound to actin provide insight into toxin design and activity

1 reference

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21 January 2018

Apoptosis-inducing activity of the actin-depolymerizing agent aplyronine A and its side-chain derivatives

1 reference

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The exploration of macrocycles for drug discovery--an underexploited structural class

1 reference

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Macrocycles are great cycles: applications, opportunities, and challenges of synthetic macrocycles in drug discovery

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Macrocyclic drugs and clinical candidates: what can medicinal chemists learn from their properties?

1 reference

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Macrocycles: lessons from the distant past, recent developments, and future directions

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A platform for the discovery of new macrolide antibiotics.

1 reference

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21 January 2018

Total Synthesis of Swinholide A: An Exposition in Hydrogen-Mediated C-C Bond Formation

1 reference

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21 January 2018

Direct catalytic asymmetric aldol reactions of thioamides: toward a stereocontrolled synthesis of 1,3-polyols.

1 reference

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Streamlined catalytic asymmetric synthesis of atorvastatin.

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Direct aldol strategy in enantioselective total synthesis of thuggacin B.

1 reference

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Iterative direct aldol strategy for polypropionates: enantioselective total synthesis of (-)-membrenone A and B

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Iodine-catalyzed highly diastereoselective synthesis of trans-2,6-disubstituted-3,4-dihydropyrans: application to concise construction of C28-C37 bicyclic core of (+)-sorangicin A.

1 reference

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Elongation of 1,3-polyols via iterative catalyst-directed carbonyl allylation from the alcohol oxidation level

1 reference

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Protecting-group-free diastereoselective C-C coupling of 1,3-glycols and allyl acetate through site-selective primary alcohol dehydrogenation

1 reference

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21 January 2018

Formal Synthesis of Premisakinolide A and C(19)-C(32) of Swinholide A via Site-Selective C-H Allylation and Crotylation of Unprotected Diols

1 reference

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Direct generation of acyclic polypropionate stereopolyads via double diastereo- and enantioselective iridium-catalyzed crotylation of 1,3-diols: beyond stepwise carbonyl addition in polyketide construction

1 reference

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Catalyst-directed diastereo- and site-selectivity in successive nucleophilic and electrophilic allylations of chiral 1,3-diols: protecting-group-free synthesis of substituted pyrans

1 reference

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Preparation of Chiral Allenylmetal Reagents from Enantioenriched Allenyl Iodides and Propargylic Mesylates. A Comparison of Indium, Bismuth, and Tin Derivatives

1 reference

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21 January 2018

Highly stereocontrolled synthesis of trans-2,6-disubstituted-5-methyl-3,6-dihydropyrans: stereoselective synthesis of the bicyclic core of penostatin B.

1 reference

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21 January 2018

Highly stereoselective synthesis of anti,anti-dipropionate stereotriads: a solution to the long-standing problem of challenging mismatched double asymmetric crotylboration reactions

1 reference

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21 January 2018

Study of the interaction between actin and antitumor substance aplyronine A with a novel fluorescent photoaffinity probe

1 reference

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21 January 2018

Asymmetric synthesis using diisopropyl tartrate modified (E)- and (Z)-crotylboronates: preparation of the chiral crotylboronates and reactions with achiral aldehydes

1 reference

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Toxins from cyanophytes belonging to the scytonemataceae

1 reference

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https://opencitations.net/index/coci/api/v1/citations/10.1351/PAC198658020263

Isolation of swinholide A and related glycosylated derivatives from two field collections of marine cyanobacteria

1 reference

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Studies on catalytic enantioselective total synthesis of caprazamycin B: construction of the western zone

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The isolation of a monomeric carboxylic acid of swinholide a from the indo-pacific sponge, theonella swinhoei

1 reference

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Total synthesis of scytophycin C. 1. Stereoselective syntheses of the C(1)-C(18) segment and the C(19)-C(31) segment

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Scytophycins, cytotoxic and antimycotic agents from the cyanophyte Scytonema pseudohofmanni

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Catalytic asymmetric dihydroxylation using phenoxyethoxymethyl-polystyrene (PEM)-based novel microencapsulated osmium tetroxide (PEM-MC OsO4)

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Direct catalytic enantio- and diastereoselective aldol reaction of thioamides

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Novel actin depolymerizing macrolide aplyronine A

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Absolute stereostructure of swinholide A, a potent cytotoxic macrolide from the Okinawan marine sponge Theonella swinhoei

1 reference

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Structural basis of swinholide A binding to actin

1 reference

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Identifiers

10.1002/CHEM.201701183

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422340%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28422340%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

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