(Q48262483)

10 February 2018

title

Decreased tonic inhibition in cerebellar granule cells causes motor dysfunction in a mouse model of Angelman syndrome. (English)

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10 February 2018

author

Shinji Saitoh

6

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10 February 2018

Atsuo Fukuda

9

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10 February 2018

author name string

Kiyoshi Egawa

1

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10 February 2018

Kyoko Kitagawa

2

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10 February 2018

Koichi Inoue

3

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10 February 2018

Masakazu Takayama

4

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10 February 2018

Chitoshi Takayama

5

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10 February 2018

Tatsuya Kishino

7

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10 February 2018

Masatoshi Kitagawa

8

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10 February 2018

language of work or name

English

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publication date

1 December 2012

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10 February 2018

Science Translational Medicine

published in

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10 February 2018

volume

4

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10 February 2018

issue

163

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10 February 2018

page(s)

163ra157

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10 February 2018

Imprinted expression of the murine Angelman syndrome gene, Ube3a, in hippocampal and Purkinje neurons

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

UBE3A/E6-AP mutations cause Angelman syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Angelman syndrome: consensus for diagnostic criteria. Angelman Syndrome Foundation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Ube3a is required for experience-dependent maturation of the neocortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Neurobehavioral and electroencephalographic abnormalities in Ube3a maternal-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Angelman syndrome reviewed from a neurophysiological perspective. The UBE3A-GABRB3 hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Emerging roles for ubiquitin and protein degradation in neuronal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Distinct phenotypes distinguish the molecular classes of Angelman syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Aberrant somatosensory-evoked responses imply GABAergic dysfunction in Angelman syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Diversity of inhibitory neurotransmission through GABA(A) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Enhanced tonic GABAA inhibition in typical absence epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Development of action potential-dependent and independent spontaneous GABAA receptor-mediated currents in granule cells of postnatal rat cerebellum

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Contributions of the GABAA receptor alpha6 subunit to phasic and tonic inhibition revealed by a naturally occurring polymorphism in the alpha6 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Glial transporters for glutamate, glycine, and GABA: II. GABA transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

GABA transporter deficiency causes tremor, ataxia, nervousness, and increased GABA-induced tonic conductance in cerebellum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Tissue-specific variation of Ube3a protein expression in rodents and in a mouse model of Angelman syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Ubiquitin-Dependent Degradation of Smad2 Is Increased in the Glomeruli of Rats with Anti-Thymocyte Serum Nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Reduction of transforming growth factor-beta type II receptor is caused by the enhanced ubiquitin-dependent degradation in human renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Oligomerization of the {gamma}-aminobutyric acid transporter-1 is driven by an interplay of polar and hydrophobic interactions in transmembrane helix II

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Concentrative export from the endoplasmic reticulum of the gamma-aminobutyric acid transporter 1 requires binding to SEC24D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Development of a tonic form of synaptic inhibition in rat cerebellar granule cells resulting from persistent activation of GABAA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Integration of quanta in cerebellar granule cells during sensory processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Adaptive regulation of neuronal excitability by a voltage-independent potassium conductance

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Pharmacological characterization of a novel cell line expressing human alpha(4)beta(3)delta GABA(A) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Analysis of cerebellar function in Ube3a-deficient mice reveals novel genotype-specific behaviors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Loss of dopaminergic neurons and resulting behavioural deficits in mouse model of Angelman syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Synaptic destabilization by neuronal Nogo-A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Plasma and CNS concentrations of Gaboxadol in rats following subcutaneous administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Rotarod studies in the rat of the GABAA receptor agonist gaboxadol: lack of ethanol potentiation and benzodiazepine cross-tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Inhibition of thalamic excitability by 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-3-ol: a selective role for delta-GABA(A) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Quantitative autoradiographic characterization of the binding of [3H]tiagabine (NNC 05-328) to the GABA uptake carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Alterations in intrinsic membrane properties and the axon initial segment in a mouse model of Angelman syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Bidirectional control of BK channel open probability by CAMKII and PKC in medial vestibular nucleus neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

[(11)C]flumazenil positron emission tomography analyses of brain gamma-aminobutyric acid type A receptors in Angelman syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Altered GABAA receptor subunit expression and pharmacology in human Angelman syndrome cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Trace fear conditioning involves hippocampal alpha5 GABA(A) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Regulation of the glutamate transporter EAAT1 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid-inducible kinase isoforms SGK1/3 and protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Developmental expression of GABA transporter-1 and 3 during formation of the GABAergic synapses in the mouse cerebellar cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Genomic imprinting of experience-dependent cortical plasticity by the ubiquitin ligase gene Ube3a

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Deletion of the GABA(A) receptor alpha1 subunit increases tonic GABA(A) receptor current: a role for GABA uptake transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Fbw7 promotes ubiquitin-dependent degradation of c-Myb: involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Interaction of neuron-specific K+-Cl- cotransporter, KCC2, with brain-type creatine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Enhanced Mdm2 activity inhibits pRB function via ubiquitin-dependent degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

Whole-cell and single-channel currents activated by GABA and glycine in granule cells of the rat cerebellum

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

APCCdh1 mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004655

10.1126/SCITRANSLMED.3004655

21 January 2018

Identifiers

DOI

1 reference

10 February 2018

1 reference

10 February 2018