(Q46022696)

18 December 2017

title

Fbw7 promotes ubiquitin-dependent degradation of c-Myb: involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb. (English)

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18 December 2017

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K Kitagawa

1

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18 December 2017

Y Hiramatsu

2

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18 December 2017

C Uchida

3

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18 December 2017

T Isobe

4

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18 December 2017

T Hattori

5

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18 December 2017

T Oda

6

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18 December 2017

K Shibata

7

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18 December 2017

S Nakamura

8

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18 December 2017

A Kikuchi

9

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18 December 2017

M Kitagawa

10

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18 December 2017

language of work or name

English

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publication date

4 May 2009

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18 December 2017

published in

Oncogene

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18 December 2017

volume

28

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18 December 2017

issue

25

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18 December 2017

page(s)

2393-2405

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18 December 2017

https://scigraph.springernature.com/pub.10.1038/onc.2009.111

exact match

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cites work

Phosphorylation-dependent conformation and proteolytic stability of c-Myb

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Oncogenic activation of c-Myb by carboxyl-terminal truncation leads to decreased proteolysis by the ubiquitin-26S proteasome pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.111

Degradation of B-Myb by ubiquitin-mediated proteolysis: involvement of the Cdc34-SCF(p45Skp2) pathway

21 January 2018

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The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children.

21 January 2018

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GSK3 inhibitors: development and therapeutic potential

21 January 2018

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Enhanced proliferative potential of hematopoietic cells expressing degradation-resistant c-Myb mutants.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.111

Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.111

Runx1, c-Myb, and C/EBPalpha couple differentiation to proliferation or growth arrest during hematopoiesis

21 January 2018

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Production of a site- and phosphorylation state-specific antibody.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.111

Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.111

21 January 2018

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Degradation of Tob1 mediated by SCFSkp2-dependent ubiquitination

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.111

cMYB is involved in the regulation of fetal hemoglobin production in adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Differential sensitivity of v-Myb and c-Myb to Wnt-1-induced protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Fbxw7 acts as an E3 ubiquitin ligase that targets c-Myb for nemo-like kinase (NLK)-induced degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Requirement of c-myb in T cell development and in mature T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Expression of mouse Fbxw7 isoforms is regulated in a cell cycle- or p53-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL.

21 January 2018

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Mechanisms of tumor suppression by the SCF(Fbw7).

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.111

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Ubiquitin ligases: cell-cycle control and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

The myb gene family in cell growth, differentiation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Changes in gene expression associated with induced differentiation of erythroleukemia: protooncogenes, globin genes, and cell division

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.111

Proper levels of c-Myb are discretely defined at distinct steps of hematopoietic cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Deregulated c-myb disrupts interleukin-6- or leukemia inhibitory factor-induced myeloid differentiation prior to c-myc: role in leukemogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.111

The Notch1/c-Myc pathway in T cell leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.111

Studies of the human c-myb gene and its product in human acute leukemias

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.111

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF(Fbw7).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

p53 suppresses the c-Myb-induced activation of heat shock transcription factor 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent inhibition of GSK-3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Enhanced Mdm2 activity inhibits pRB function via ubiquitin-dependent degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Coordination of erythropoiesis by the transcription factor c-Myb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Wnt5a modulates glycogen synthase kinase 3 to induce phosphorylation of receptor tyrosine kinase Ror2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Hyperphosphorylation and increased proteolytic breakdown of c-Myb induced by the inhibition of Ser/Thr protein phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Differential expression of the oncoproteins c-myc and c-myb in human lymphoproliferative disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

Identification of protein instability determinants in the carboxy-terminal region of c-Myb removed as a result of retroviral integration in murine monocytic leukemias

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.111

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7 January 2021

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Identifiers

DOI

10.1038/ONC.2009.111

1 reference

18 December 2017

Dimensions Publication ID

0 references

1 reference

18 December 2017