(Q43167778)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18367647%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18367647%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

8

1 reference

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4 January 2020

Toshio Suda

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18367647%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Fumio Arai

5

1 reference

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4 January 2020

Yumi Matsuzaki

18

1 reference

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4 January 2020

4

Atsushi Iwama

1 reference

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4 January 2020

author name string

Sahoko Matsuoka

1

1 reference

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4 January 2020

Yuichi Oike

2

1 reference

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4 January 2020

Ichiro Onoyama

3

1 reference

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4 January 2020

Keiyo Takubo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18367647%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Yoichi Mashimo

7

1 reference

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4 January 2020

Eriko Nitta

9

1 reference

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4 January 2020

Keisuke Ito

10

1 reference

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4 January 2020

Kana Miyamoto

11

1 reference

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4 January 2020

Hiroki Yoshiwara

12

1 reference

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4 January 2020

Kentaro Hosokawa

13

1 reference

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4 January 2020

Yuka Nakamura

14

1 reference

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4 January 2020

Yumiko Gomei

15

1 reference

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4 January 2020

Hiroko Iwasaki

16

1 reference

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4 January 2020

Yasuhide Hayashi

17

1 reference

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4 January 2020

Keiko Nakayama

19

1 reference

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4 January 2020

Yasuo Ikeda

20

1 reference

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4 January 2020

Akira Hata

21

1 reference

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4 January 2020

Shigeru Chiba

22

1 reference

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4 January 2020

Keiichi I Nakayama

23

1 reference

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4 January 2020

publication date

26 March 2008

1 reference

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4 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18367647%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

volume

22

1 reference

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4 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18367647%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

page(s)

986-991

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18367647%20AND%20SRC:MED&resulttype=core&format=json

Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis

4 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

CARF binds to three members (ARF, p53, and HDM2) of the p53 tumor-suppressor pathway.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Ubiquitin ligases: cell-cycle control and cancer

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Mechanisms of tumor suppression by the SCF(Fbw7).

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Tumour biology: senescence in premalignant tumours

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Ubiquitin and ubiquitin-like proteins as multifunctional signals

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Tumor suppressor activities of the Fbw7 E3 ubiquitin ligase receptor

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Inactivation of hCDC4 can cause chromosomal instability

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Mutation of hCDC4 leads to cell cycle deregulation of cyclin E in cancer.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Osteoblastic cells regulate the haematopoietic stem cell niche

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Identification of the haematopoietic stem cell niche and control of the niche size

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

hCDC4 gene mutations in endometrial cancer

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2335330

Suppression of p53 by Notch in lymphomagenesis: implications for initiation and regression

15 August 2018

1 reference

12 December 2020

Molecular pathways in T-cell acute lympho-blastic leukemia: ramifications for therapy

1 reference

12 December 2020

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

1 reference

12 December 2020

Hematopoietic stem cell quiescence maintained by p21cip1/waf1

1 reference

12 December 2020

Identifiers

DOI

10.1101/GAD.1621808

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18367647%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18367647%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

PubMed publication ID

18367647

1 reference