(Q48271519)

English

Cyclin-dependent kinase-5 is involved in neuregulin-dependent activation of phosphatidylinositol 3-kinase and Akt activity mediating neuronal survival.

scientific article published on 24 June 2003

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scholarly article

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

Cyclin-dependent kinase-5 is involved in neuregulin-dependent activation of phosphatidylinositol 3-kinase and Akt activity mediating neuronal survival. (English)

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

author name string

Bing-Sheng Li

1

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

Wu Ma

2

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

Howard Jaffe

3

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

Yali Zheng

4

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

Satoru Takahashi

5

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

Lei Zhang

6

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

Ashok B Kulkarni

7

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

Harish C Pant

8

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

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publication date

24 June 2003

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

Journal of Biological Chemistry

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Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

278

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Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

35702-35709

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

37

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Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

Neuronal cdc2-like kinase: a cdc2-related protein kinase with predominantly neuronal expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

A brain-specific activator of cyclin-dependent kinase 5.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Reelin signaling and Cdk5 in the control of neuronal positioning

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Regulation of Munc-18/syntaxin 1A interaction by cyclin-dependent kinase 5 in nerve endings

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Regulation of exocytosis by cyclin-dependent kinase 5 via phosphorylation of Munc18

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Amphiphysin 1 binds the cyclin-dependent kinase (cdk) 5 regulatory subunit p35 and is phosphorylated by cdk5 and cdc2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Regulation of NMDA receptors by cyclin-dependent kinase-5

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Neurotoxicity induces cleavage of p35 to p25 by calpain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

p35nck5a and cyclin-dependent kinase 5 colocalize in Lewy bodies of brains with Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Niemann-Pick disease type C yields possible clue for why cerebellar neurons do not form neurofibrillary tangles.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Callosal axon guidance defects in p35(-/-) mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Role of neuregulins in glial cell development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Identification of heregulin, a specific activator of p185erbB2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Ligands for ErbB-family receptors encoded by a neuregulin-like gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Neuregulins and their receptors: a versatile signaling module in organogenesis and oncogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Multiple essential functions of neuregulin in development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Neuregulins and neuregulin receptors in neural development.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Aberrant development of motor axons and neuromuscular synapses in erbB2-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Neu differentiation factor is a neuron-glia signal and regulates survival, proliferation, and maturation of rat Schwann cell precursors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Neuregulin and erbB receptors play a critical role in neuronal migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Glial growth factor restricts mammalian neural crest stem cells to a glial fate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

T cell activation-dependent association between the p85 subunit of the phosphatidylinositol 3-kinase and Grb2/phospholipase C-gamma 1-binding phosphotyrosyl protein pp36/38.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Neuregulin and ErbB receptor signaling pathways in the nervous system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

cdc2-like kinase from rat spinal cord specifically phosphorylates KSPXK motifs in neurofilament proteins: isolation and characterization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Cloning of the rat ErbB3 cDNA and characterization of the recombinant protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Isolation of the neu/HER-2 stimulatory ligand: a 44 kd glycoprotein that induces differentiation of mammary tumor cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Heregulin stimulates mitogenesis and phosphatidylinositol 3-kinase in mouse fibroblasts transfected with erbB2/neu and erbB3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Gene expression induced by cerebral ischemia: an apoptotic perspective

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Cell death during development of the nervous system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Neuronal cell death.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Cdk5 behind the wheel: a role in trafficking and transport?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Mechanism of protein kinase B activation by cyclic AMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Biochemical characterization of the protein tyrosine kinase homology domain of the ErbB3 (HER3) receptor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Activation of the phosphatidylinositol 3-kinase-Akt/protein kinase B signaling pathway in arachidonic acid-stimulated human myeloid and endothelial cells: involvement of the ErbB receptor family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302004200

21 January 2018

Identifiers

10.1074/JBC.M302004200

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/12824184

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