(Q48275808)

English

Genistein promotes the metabolic transformation of acetaminophen to glucuronic acid in human L-O2, HepG2 and Hep3b cells via the Nrf2/Keap1 pathway.

scientific article published on 26 October 2016

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scholarly article

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26 March 2020

Genistein promotes the metabolic transformation of acetaminophen to glucuronic acid in human L-O2, HepG2 and Hep3b cells via the Nrf2/Keap1 pathway (English)

1 reference

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26 March 2020

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26 March 2020

author name string

Wei Wei

2

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26 March 2020

Luo Jian-Ping

3

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26 March 2020

Jin Yu-Xia

4

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26 March 2020

Dai Zi-Ling

5

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26 March 2020

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1 November 2016

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26 March 2020

Food & Function

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26 March 2020

7

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26 March 2020

11

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26 March 2020

4683-4692

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26 March 2020

Comparison of flavonoids and isoflavonoids as antioxidants

1 reference

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21 January 2018

Dietary flavonoids: effects on xenobiotic and carcinogen metabolism

1 reference

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21 January 2018

Genistein protection against acetaminophen-induced liver injury via its potential impact on the activation of UDP-glucuronosyltransferase and antioxidant enzymes

1 reference

https://api.crossref.org/works/10.1039%2FC6FO00889E

21 January 2018

Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice

1 reference

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21 January 2018

The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation

1 reference

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21 January 2018

The predicted molecular weight of Nrf2: it is what it is not.

1 reference

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21 January 2018

Targeting the redox sensitive Nrf2-Keap1 defense pathway in cardiovascular disease: protection afforded by dietary isoflavones

1 reference

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21 January 2018

Dietary isoflavones and vascular protection: activation of cellular antioxidant defenses by SERMs or hormesis?

1 reference

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21 January 2018

Dietary phytochemicals and cancer prevention: Nrf2 signaling, epigenetics, and cell death mechanisms in blocking cancer initiation and progression.

1 reference

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21 January 2018

Ginsenoside Rb1 protects against 6-hydroxydopamine-induced oxidative stress by increasing heme oxygenase-1 expression through an estrogen receptor-related PI3K/Akt/Nrf2-dependent pathway in human dopaminergic cells.

1 reference

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21 January 2018

Nutritional strategies to modulate inflammation and oxidative stress pathways via activation of the master antioxidant switch Nrf2.

1 reference

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21 January 2018

Caffeic acid prevents acetaminophen-induced liver injury by activating the Keap1-Nrf2 antioxidative defense system

1 reference

https://api.crossref.org/works/10.1039%2FC6FO00889E

21 January 2018

Flavones: an important scaffold for medicinal chemistry

1 reference

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21 January 2018

A review of acetaminophen poisoning

1 reference

https://api.crossref.org/works/10.1039%2FC6FO00889E

21 January 2018

Cytotoxicity of paracetamol and 3,5-dihalogenated analogues: Role of cytochrome P-450 and formation of GSH conjugates and protein adducts.

1 reference

https://api.crossref.org/works/10.1039%2FC6FO00889E

21 January 2018

Genistein as a neuroprotective antioxidant attenuates redox imbalance induced by beta-amyloid peptides 25-35 in PC12 cells

1 reference

https://api.crossref.org/works/10.1039%2FC6FO00889E

21 January 2018

Metabolism and disposition of acetaminophen: recent advances in relation to hepatotoxicity and diagnosis

1 reference

https://api.crossref.org/works/10.1039%2FC6FO00889E

21 January 2018

UDP-glucuronosyltransferase 1A6: structural, functional, and regulatory aspects

1 reference

https://api.crossref.org/works/10.1039%2FC6FO00889E

21 January 2018

Nrf2-Keap1 defines a physiologically important stress response mechanism

1 reference

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21 January 2018

Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression.

1 reference

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21 January 2018

Fenofibrate activates Nrf2 through p62-dependent Keap1 degradation

1 reference

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21 January 2018

The rise of antioxidant signaling--the evolution and hormetic actions of Nrf2.

1 reference

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21 January 2018

The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin

1 reference

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21 January 2018

Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice

1 reference

https://api.crossref.org/works/10.1039%2FC6FO00889E

21 January 2018

Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway

1 reference

https://api.crossref.org/works/10.1039%2FC6FO00889E

21 January 2018

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

1 reference

https://api.crossref.org/works/10.1039%2FC6FO00889E

21 January 2018

NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection

1 reference

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21 January 2018

Nrf2 and the promotion of atherosclerosis: lessons to be learned

1 reference

https://api.crossref.org/works/10.1039%2FC6FO00889E

21 January 2018

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

1 reference

https://api.crossref.org/works/10.1039%2FC6FO00889E

21 January 2018

The complexity of the Nrf2 pathway: beyond the antioxidant response

1 reference

https://api.crossref.org/works/10.1039%2FC6FO00889E

21 January 2018

α-Lipoic acid protects against the cytotoxicity and oxidative stress induced by cadmium in HepG2 cells through regeneration of glutathione by glutathione reductase via Nrf2/ARE signaling pathway

1 reference

https://api.crossref.org/works/10.1039%2FC6FO00889E

21 January 2018

Activation of glutathione peroxidase via Nrf1 mediates genistein's protection against oxidative endothelial cell injury

1 reference

https://api.crossref.org/works/10.1039%2FC6FO00889E

21 January 2018

Genistein attenuates ischemic oxidative damage and behavioral deficits via eNOS/Nrf2/HO-1 signaling.

1 reference

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21 January 2018

Identifiers

10.1039/C6FO00889E

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27781231%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27781231%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

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