(Q48290310)

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Paracrine Factors Secreted by MSCs Promote Astrocyte Survival Associated With GFAP Downregulation After Ischemic Stroke via p38 MAPK and JNK.

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/25752945

Paracrine Factors Secreted by MSCs Promote Astrocyte Survival Associated With GFAP Downregulation After Ischemic Stroke via p38 MAPK and JNK. (English)

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PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/25752945

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5 June 2020

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Weiyi Huang

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5 June 2020

Bingke Lv

2

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5 June 2020

Huijun Zeng

3

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5 June 2020

Dandan Shi

4

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5 June 2020

Yi Liu

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5 June 2020

Fanfan Chen

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5 June 2020

Xinghui Liu

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5 June 2020

Rong Zhu

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5 June 2020

Lei Yu

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5 June 2020

Xiaodan Jiang

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5 June 2020

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1 October 2015

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10 February 2018

http://europepmc.org/abstract/MED/25752945

Journal of Cellular Physiology

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5 June 2020

230

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5 June 2020

10

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5 June 2020

2461-2475

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5 June 2020

Stem cell therapy for cerebral ischemia: from basic science to clinical applications

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Mesenchymal stem cell conditioned media attenuates in vitro and ex vivo myocardial reperfusion injury.

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Mesenchymal stem cells in joint disease and repair.

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Lymphocyte cell kinase activation mediates neuroprotection during ischemic preconditioning

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Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia

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Cell type-specific activation of p38 MAPK in the brain regions of hypoxic preconditioned mice

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Pathophysiology of ischaemia-reperfusion injury

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Astrocytic modulation of blood brain barrier: perspectives on Parkinson's disease.

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Acrylamide-induced astrogliotic and apoptotic responses in human astrocytoma cells.

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Transplantation of bone marrow-derived MSCs improves cisplatinum-induced renal injury through paracrine mechanisms.

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Molecular signalling mediating the protective effect of A1 adenosine and mGlu3 metabotropic glutamate receptor activation against apoptosis by oxygen/glucose deprivation in cultured astrocytes

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A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

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Neuronal caspase-3 signaling: not only cell death

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Recent molecular approaches to understanding astrocyte function in vivo

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Intermediate filaments are important for astrocyte response to oxidative stress induced by oxygen-glucose deprivation and reperfusion

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Pathobiology of injury after stroke: the neurovascular unit and beyond

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Intranasally administered mesenchymal stem cells promote a regenerative niche for repair of neonatal ischemic brain injury

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Therapeutic applications of mesenchymal stromal cells: paracrine effects and potential improvements

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Nanotubular crosstalk with distressed cardiomyocytes stimulates the paracrine repair function of mesenchymal stem cells.

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IL-27 abrogates receptor activator of NF-kappa B ligand-mediated osteoclastogenesis of human granulocyte-macrophage colony-forming unit cells through STAT1-dependent inhibition of c-Fos.

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21 January 2018

Bone marrow stromal cells increase astrocyte survival via upregulation of phosphoinositide 3-kinase/threonine protein kinase and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways and stimulate astrocyte trophic f

1 reference

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21 January 2018

Bone marrow stromal cells reduce ischemia-induced astrocytic activation in vitro

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21 January 2018

Traumatic scratch injury in astrocytes triggers calcium influx to activate the JNK/c-Jun/AP-1 pathway and switch on GFAP expression.

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Paracrine mechanisms in adult stem cell signaling and therapy

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21 January 2018

Advances and challenges in treatment and prevention of ischemic stroke

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17β-Estradiol prevents cell death and mitochondrial dysfunction by an estrogen receptor-dependent mechanism in astrocytes after oxygen-glucose deprivation/reperfusion

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21 January 2018

Dysfunctional cell-cell signaling in the neurovascular unit as a paradigm for central nervous system disease

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c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

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Umbilical cord tissue-derived mesenchymal stem cells induce apoptosis in PC-3 prostate cancer cells through activation of JNK and downregulation of PI3K/AKT signaling.

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A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis

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Mesenchymal stem cells: therapeutic outlook for stroke.

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Tanshinone IIA dampens the cell proliferation induced by ischemic insult in rat astrocytes via blocking the activation of HIF-1α/SDF-1 signaling

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21 January 2018

Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association

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Upregulation of glutamate transporter GLT-1 by mTOR-Akt-NF-кB cascade in astrocytic oxygen-glucose deprivation

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Neuroprotective effects of bilobalide on cerebral ischemia and reperfusion injury are associated with inhibition of pro-inflammatory mediator production and down-regulation of JNK1/2 and p38 MAPK activation.

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Activation of p38 mitogen-activated protein kinase is required for in vivo brain-derived neurotrophic factor production in the rat hippocampus

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STAT1 as a key modulator of cell death

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Role of p38 and JNK in liver ischemia and reperfusion

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Role of p38 MAP Kinase Signal Transduction in Solid Tumors

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Functions of astrocytes and their potential as therapeutic targets

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Mesenchymal stem cells that produce neurotrophic factors reduce ischemic damage in the rat middle cerebral artery occlusion model

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An overview of stress response and hypometabolic strategies in Caenorhabditis elegans: conserved and contrasting signals with the mammalian system

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Paracrine factors from mesenchymal stem cells: a proposed therapeutic tool for acute lung injury and acute respiratory distress syndrome

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The p-ERK-p-c-Jun-cyclinD1 pathway is involved in proliferation of smooth muscle cells after exposure to cigarette smoke extract.

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Paracrine mechanisms of mesenchymal stem cell-based therapy: current status and perspectives.

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Phosphatase Wip1 negatively regulates neutrophil development through p38 MAPK-STAT1.

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Mesenchymal stem cells inhibit lipopolysaccharide-induced inflammatory responses of BV2 microglial cells through TSG-6.

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CaMKII activates ASK1 to induce apoptosis of spinal astrocytes under oxygen-glucose deprivation

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Mechanisms involved in the therapeutic properties of mesenchymal stem cells

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Involvement of mitogen-activated protein kinase pathways in expression of the water channel protein aquaporin-4 after ischemia in rat cortical astrocytes

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Role of the JNK pathway in human diseases

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"Super p53" mice display retinal astroglial changes.

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Immunomodulatory influence of bone marrow-derived mesenchymal stem cells on neuroinflammation in astrocyte cultures

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Mesenchymal stromal cells rescue cortical neurons from apoptotic cell death in an in vitro model of cerebral ischemia

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Astrocyte responses to injury: VEGF simultaneously modulates cell death and proliferation

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Molecular dissection of reactive astrogliosis and glial scar formation

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In vitro toxicity of particulate matter (PM) collected at different sites in the Netherlands is associated with PM composition, size fraction and oxidative potential--the RAPTES project

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p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents

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Mesenchymal stem cell therapy for treatment of cardiovascular disease: helping people sooner or later

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p53: death star

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Signal integration by JNK and p38 MAPK pathways in cancer development

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Roles of activated astrocytes in bone marrow stromal cell proliferation and differentiation

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Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition

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Oxygen-glucose deprivation induced glial scar-like change in astrocytes

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Multipotent mesenchymal stromal cells decrease transforming growth factor β1 expression in microglia/macrophages and down-regulate plasminogen activator inhibitor 1 expression in astrocytes after stroke

1 reference

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Multipotent mesenchymal stromal cells increase tPA expression and concomitantly decrease PAI-1 expression in astrocytes through the sonic hedgehog signaling pathway after stroke (in vitro study).

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Repeated preconditioning with hyperbaric oxygen induces neuroprotection against forebrain ischemia via suppression of p38 mitogen activated protein kinase

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Blocking epidermal growth factor receptor attenuates reactive astrogliosis through inhibiting cell cycle progression and protects against ischemic brain injury in rats.

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Transplantation of mesenchymal stem cells exerts anti-apoptotic effects in adult rats after spinal cord ischemia-reperfusion injury

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Genomic analysis of reactive astrogliosis

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21 January 2018

Targeting astrocytes for stroke therapy

1 reference

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Identifiers

10.1002/JCP.24981

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25752945%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25752945%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

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