(Q48352739)

English

A gain-of-function mutation in synaptotagmin-1 reveals a critical role of Ca2+-dependent soluble N-ethylmaleimide-sensitive factor attachment protein receptor complex binding in synaptic exocytosis.

scientific article published in November 2006

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17135417%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

A gain-of-function mutation in synaptotagmin-1 reveals a critical role of Ca2+-dependent soluble N-ethylmaleimide-sensitive factor attachment protein receptor complex binding in synaptic exocytosis (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17135417%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

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inferred from title

Christian Rosenmund

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17135417%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Zhiping P. Pang

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17135417%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Thomas C. Südhof

5

object named as

Thomas C Südhof

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17135417%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

2

object named as

Ok-Ho Shin

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17135417%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

author name string

Alexander C Meyer

3

1 reference

Europe PubMed Central

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22 December 2019

language of work or name

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publication date

1 November 2006

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Europe PubMed Central

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22 December 2019

number of pages

10

0 references

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17135417%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

26

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17135417%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

48

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17135417%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

12556-12565

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17135417%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Probing fundamental aspects of synaptic transmission with strontium

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptotagmin I functions as a calcium regulator of release probability

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The C2B domain of synaptotagmin I is a Ca2+-binding module.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptotagmin modulation of fusion pore kinetics in regulated exocytosis of dense-core vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Short-term synaptic plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+-dependent synaptotagmin binding to SNAP-25 is essential for Ca2+-triggered exocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure/function analysis of Ca2+ binding to the C2A domain of synaptotagmin 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of calcium-independent synaptotagmin binding to target SNAREs

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sr2+ binding to the Ca2+ binding site of the synaptotagmin 1 C2B domain triggers fast exocytosis without stimulating SNARE interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane fusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synaptotagmin C2A domain is part of the calcium sensor controlling fast synaptic transmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Examining synaptotagmin 1 function in dense core vesicle exocytosis under direct control of Ca2+

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HPC-1 is associated with synaptotagmin and omega-conotoxin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptotagmin interaction with the syntaxin/SNAP-25 dimer is mediated by an evolutionarily conserved motif and is sensitive to inositol hexakisphosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fusion pore dynamics are regulated by synaptotagmin*t-SNARE interactions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synaptic vesicle cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-molecule studies of synaptotagmin and complexin binding to the SNARE complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SNARE complexes prepare for membrane fusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autonomous function of synaptotagmin 1 in triggering synchronous release independent of asynchronous release

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and function of SNARE and SNARE-interacting proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol phosphates as co-activators of Ca2+ binding to C2 domains of synaptotagmin 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Domain structure of synaptotagmin (p65)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrostatic and hydrophobic interactions of synapsin I and synapsin I fragments with phospholipid bilayers

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipids of synaptic vesicles: relevance to the mechanism of membrane fusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complexins: cytosolic proteins that regulate SNAP receptor function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+ regulates the interaction between synaptotagmin and syntaxin 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium-dependent interaction of the cytoplasmic region of synaptotagmin with membranes. Autonomous function of a single C2-homologous domain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of synaptotagmin-binding domains on syntaxin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Definition of the readily releasable pool of vesicles at hippocampal synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SNAP-25 is required for a late postdocking step in Ca2+-dependent exocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+ binding to synaptotagmin: how many Ca2+ ions bind to the tip of a C2-domain?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17135417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.3804-06.2006

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17135417%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17135417%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17135417%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

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