(Q48357484)

10 February 2018

review article

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title

Transgenic and knockout mice in research on prion diseases (English)

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10 February 2018

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Raeber AJ

1

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10 February 2018

Brandner S

2

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10 February 2018

Klein MA

3

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10 February 2018

Benninger Y

4

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10 February 2018

Musahl C

5

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10 February 2018

Frigg R

6

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10 February 2018

Roeckl C

7

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10 February 2018

Fischer MB

8

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10 February 2018

Weissmann C

9

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10 February 2018

Aguzzi A

10

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10 February 2018

publication date

1 October 1998

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10 February 2018

published in

Brain Pathology

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10 February 2018

volume

8

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10 February 2018

issue

4

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10 February 2018

page(s)

715-733

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10 February 2018

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Normal host prion protein necessary for scrapie-induced neurotoxicity.

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The cellular prion protein binds copper in vivo

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Role of microglia and host prion protein in neurotoxicity of a prion protein fragment.

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Transmission of bovine spongiform encephalopathy and scrapie to mice: strain variation and the species barrier

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Biological evidence that scrapie agent has an independent genome

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Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent

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Mice devoid of PrP are resistant to scrapie

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Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

21 January 2018

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Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice

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Cellular isoform of the scrapie agent protein participates in lymphocyte activation

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Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain

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MRI assessment of the blood-brain barrier in a hamster model of scrapie.

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BSE: a decade on--Part I.

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Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.

21 January 2018

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Prion protein is necessary for normal synaptic function

21 January 2018

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Selective neuronal targeting in prion disease

21 January 2018

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Identification of a gene which controls the incubation period of some strains of scrapie agent in mice

21 January 2018

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Scrapie-associated prion protein accumulates in astrocytes during scrapie infection

21 January 2018

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Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible

21 January 2018

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Letter: Hepatitis with hindsight

21 January 2018

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Pathogenesis of Scrapie Virus Infection in the Mouse

21 January 2018

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Neurotoxicity of a prion protein fragment

21 January 2018

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Neuronal spread of scrapie agent and targeting of lesions within the retino-tectal pathway

21 January 2018

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Pathogenesis of Scrapie in the Mouse: the Role of the Spleen

21 January 2018

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Ionising radiation has no influence on scrapie incubation period in mice

21 January 2018

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Transmissible and non-transmissible amyloidoses: autocatalytic post-translational conversion of host precursor proteins to beta-pleated sheet configurations

21 January 2018

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Transmissible familial Creutzfeldt-Jakob disease associated with five, seven, and eight extra octapeptide coding repeats in the PRNP gene

21 January 2018

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Mutations in familial Creutzfeldt-Jakob disease and Gerstmann-Sträussler-Scheinker's syndrome

21 January 2018

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Self-replication and scrapie

21 January 2018

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Molecular pathology of scrapie-associated fibril protein (PrP) in mouse brain affected by the ME7 strain of scrapie

21 January 2018

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Copper binding to the N-terminal tandem repeat regions of mammalian and avian prion protein.

21 January 2018

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Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome

21 January 2018

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Spontaneous neurodegeneration in transgenic mice with mutant prion protein

21 January 2018

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Are Sinc and the PrP gene congruent? Evidence from PrP gene analysis in Sinc congenic mice

21 January 2018

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Linkage of the scrapie-associated fibril protein (PrP) gene and Sinc using congenic mice and restriction fragment length polymorphism analysis

21 January 2018

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Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform

21 January 2018

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Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

21 January 2018

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Pathogenesis of mouse scrapie. Evidence for direct neural spread of infection to the CNS after injection of sciatic nerve.

21 January 2018

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Evidence that the Transmission of One Source of Scrapie Agent to Hamsters Involves Separation of Agent Strains from a Mixture

21 January 2018

1 reference

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Pathogenesis of mouse scrapie: Effect of route of inoculation on infectivity titres and dose-response curves

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Pathogenesis of scrapie (strain 263K) in hamsters infected intracerebrally, intraperitoneally or intraocularly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Pathogenesis of scrapie in mice after intragastric infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Bovine spongiform encephalopathy. Epidemiology, low dose exposure and risks

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Prion (PrPSc)-specific epitope defined by a monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Complementary hydropathy identifies a cellular prion protein receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

A protease-resistant protein is a structural component of the scrapie prion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Mice with gene targetted prion protein alterations show that Prnp, Sinc and Prni are congruent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Transgenic analysis of prion diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Double replacement gene targeting for the production of a series of mouse strains with different prion protein gene alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Developmental expression of the prion protein gene in glial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Heritable disorder resembling neuronal storage disease in mice expressing prion protein with deletion of an alpha-helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

A cellular gene encodes scrapie PrP 27-30 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Molecular basis of phenotypic variability in sporadic Creutzfeldt-Jakob disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Novel proteinaceous infectious particles cause scrapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

21 January 2018

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Molecular biology of prion diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

21 January 2018

Inherited prion diseases

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https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Prion diseases and the BSE crisis

21 January 2018

1 reference

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Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Scrapie prions aggregate to form amyloid-like birefringent rods

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.

21 January 2018

1 reference

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Scrapie infectivity found in resistant species.

21 January 2018

1 reference

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Neuron-specific expression of a hamster prion protein minigene in transgenic mice induces susceptibility to hamster scrapie agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

The human 37-kDa laminin receptor precursor interacts with the prion protein in eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

NMR structure of the mouse prion protein domain PrP(121-231)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells

21 January 2018

1 reference

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No propagation of prions in mice devoid of PrP.

21 January 2018

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Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene.

21 January 2018

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Prion protein gene variation among primates

21 January 2018

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Conjunctival instillation of scrapie in mice can produce disease

21 January 2018

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Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques.

21 January 2018

1 reference

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Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Chimeric prion protein expression in cultured cells and transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice

21 January 2018

1 reference

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Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions.

21 January 2018

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Biochemical typing of scrapie strains

21 January 2018

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Scrapie prion protein contains a phosphatidylinositol glycolipid

21 January 2018

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Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice.

21 January 2018

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Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity

21 January 2018

1 reference

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Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein

21 January 2018

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Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein

21 January 2018

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A 'unified theory' of prion propagation

21 January 2018

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The Ninth Datta Lecture. Molecular biology of transmissible spongiform encephalopathies

21 January 2018

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A novel progressive spongiform encephalopathy in cattle

21 January 2018

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Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins

21 January 2018

1 reference

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Distinct prion proteins in short and long scrapie incubation period mice

21 January 2018

1 reference

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Paradoxical shortening of scrapie incubation times by expression of prion protein transgenes derived from long incubation period mice

21 January 2018

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Bovine spongiform encephalopathy: epidemiological features 1985 to 1990

21 January 2018

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A new variant of Creutzfeldt-Jakob disease in the UK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Identification of candidate proteins binding to prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Neuro-immune connection in spread of prions in the body?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

21 January 2018

A suspicious signature

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

The same prion strain causes vCJD and BSE

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Type of prion protein in UK farmers with Creutzfeldt-Jakob disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Rescue of neurophysiological phenotype seen in PrP null mice by transgene encoding human prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

BSE transmission to macaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

Altered circadian activity rhythms and sleep in mice devoid of prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.1998.TB00197.X

10.1111/J.1750-3639.1998.TB00197.X

21 January 2018

Identifiers

DOI

1 reference

10 February 2018

1 reference

10 February 2018