(Q48385313)

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Decreased axonal transport rates in the Tg2576 APP transgenic mouse: improvement with the gamma-secretase inhibitor MRK-560 as detected by manganese-enhanced MRI.

scientific article published on 10 September 2012

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12 February 2020

Decreased axonal transport rates in the Tg2576 APP transgenic mouse: improvement with the gamma-secretase inhibitor MRK-560 as detected by manganese-enhanced MRI (English)

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12 February 2020

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Fu-Hua Wang

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12 February 2020

Paulina Appelkvist

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12 February 2020

Tomas Klason

3

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Anna Bogstedt

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Kristina Eliason

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12 February 2020

Stefan Martinsson

7

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12 February 2020

Sveinn Briem

8

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Anders Andersson

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12 February 2020

Sandra A G Visser

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Magnus Ivarsson

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12 February 2020

Mattias Lindberg

12

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12 February 2020

Karin Agerman

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10 September 2012

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European Journal of Neuroscience

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3165-3172

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12 February 2020

In vivo characterization of Abeta(40) changes in brain and cerebrospinal fluid using the novel gamma-secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) in the rat.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

Improved neuronal tract tracing using manganese enhanced magnetic resonance imaging with fast T(1) mapping.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

4-substituted cyclohexyl sulfones as potent, orally active gamma-secretase inhibitors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

The olfactory bulbs in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

Interactions of colchicine with tubulin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

GSK3: a possible link between beta amyloid peptide and tau protein.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

Neuropsychology of cognitive ageing, minimal cognitive impairment, Alzheimer's disease, and vascular cognitive impairment

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

In vivo trans-synaptic tract tracing from the murine striatum and amygdala utilizing manganese enhanced MRI (MEMRI).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

Axonal transport of manganese and its relevance to selective neurotoxicity in the rat basal ganglia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

In vivo axonal transport rates decrease in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

R-flurbiprofen improves axonal transport in the Tg2576 mouse model of Alzheimer's disease as determined by MEMRI.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

Aryl sulfones: a new class of gamma-secretase inhibitors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

Brain Abeta amyloidosis in APPsw mice induces accumulation of presenilin-1 and tau.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

Oral treatment with a gamma-secretase inhibitor improves long-term potentiation in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2012.08258.X

21 January 2018

Identifiers

10.1111/J.1460-9568.2012.08258.X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22958226%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22958226%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

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