(Q42976903)

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Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons.

scientific article published on July 2010

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610750%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610750%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Michael A. Silverman

5

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7 February 2020

2

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7 February 2020

Sérgio Teixeira Ferreira

4

object named as

Sergio T Ferreira

1 reference

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7 February 2020

author name string

Helena Decker

1

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7 February 2020

Sandra M Unger

3

1 reference

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7 February 2020

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publication date

1 July 2010

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7 February 2020

Journal of Neuroscience

1 reference

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7 February 2020

30

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7 February 2020

9166-9171

1 reference

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7 February 2020

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7 February 2020

describes a project that uses

1 reference

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6632489/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate and Amyloid β-Protein Rapidly Inhibit Fast Axonal Transport in Cultured Rat Hippocampal Neurons by Different Mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble beta-amyloid1-40 induces NMDA-dependent degradation of postsynaptic density-95 at glutamatergic synapses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute effect of beta amyloid on synchronized spontaneous Ca2+ oscillations in cultured hippocampal networks.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau-dependent microtubule disassembly initiated by prefibrillar beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathways by which Abeta facilitates tau pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LTP inhibits LTD in the hippocampus via regulation of GSK3beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Culturing hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble protein oligomers as emerging toxins in Alzheimer's and other amyloid diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of GSK-3 in synaptic plasticity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A bi-directional carboxypeptidase E-driven transport mechanism controls BDNF vesicle homeostasis in hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presynaptic ryanodine receptor-CamKII signaling is required for activity-dependent capture of transiting vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular transport and kinesin superfamily proteins, KIFs: structure, function, and dynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced glycogenesis is involved in cellular senescence via GSK3/GS modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myosin Vb mobilizes recycling endosomes and AMPA receptors for postsynaptic plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria in neuroplasticity and neurological disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of Ca2+ -dependent regulation of kinesin-mediated mitochondrial motility

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GSK-3: a key player in neurodegeneration and memory.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynactin regulates bidirectional transport of dense-core vesicles in the axon and dendrites of cultured hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic targeting by A beta oligomers (ADDLS) as a basis for memory loss in early Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basic mechanisms for recognition and transport of synaptic cargos

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New insights in the biology of BDNF synthesis and release: implications in CNS function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axonal transport defects in neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposite-polarity motors activate one another to trigger cargo transport in live cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is abnormal axonal transport a cause, a contributing factor or a consequence of the neuronal pathology in Alzheimer's disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium, ischemia and excitotoxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gelsolin inhibition of fast axonal transport indicates a requirement for actin microfilaments

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau is enriched on dynamic microtubules in the distal region of growing axons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau binds to the distal axon early in development of polarity in a microtubule- and microfilament-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20610750

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.1074-10.2010

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610750%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610750%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610750%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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