(Q48385648)

11 February 2018

title

Identification of a single QTL, Mptp1, for susceptibility to MPTP-induced substantia nigra pars compacta neuron loss in mice (English)

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11 February 2018

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4

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11 February 2018

Richard J Smeyne

5

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11 February 2018

author name string

Ruby Cook

1

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11 February 2018

Lu Lu

2

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11 February 2018

Jing Gu

3

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11 February 2018

publication date

1 February 2003

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11 February 2018

published in

Molecular Brain Research

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11 February 2018

volume

110

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11 February 2018

issue

2

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11 February 2018

page(s)

279-288

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11 February 2018

Estimation of nuclear population from microtome sections

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The clinical syndrome of striatal dopamine deficiency. Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

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Developmental expression of the GIRK family of inward rectifying potassium channels: implications for abnormalities in the weaver mutant mouse

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Dopaminergic cell death induced by MPP(+), oxidant and specific neurotoxicants shares the common molecular mechanism

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Plasticity of the nigrostriatal system in MPTP-treated mice. A biochemical and morphological correlation

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The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease

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Long-term effect of MPTP in the mouse brain in relation to aging: neurochemical and immunocytochemical analysis.

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Use of quantitative trait loci to map murine lung tumor susceptibility genes

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Comparative studies on the mechanisms of paraquat and 1-methyl-4-phenylpyridine (MPP+) cytotoxicity

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7 January 2021

A genetic map of the mouse with 4,006 simple sequence length polymorphisms

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Striatal dopaminergic correlates of stable parkinsonism and degree of recovery in old-world primates one year after MPTP treatment

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Complex interactions of new quantitative trait loci, Sluc1, Sluc2, Sluc3, and Sluc4, that influence the susceptibility to lung cancer in the mouse

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DNA pooling identifies QTLs on chromosome 4 for general cognitive ability in children

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A quantitative-trait locus on chromosome 6p influences different aspects of developmental dyslexia

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7 January 2021

Time-course and dose-response study on the effects of chronic L-DOPA administration on striatal dopamine levels and dopamine transporter following MPTP toxicity.

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7 January 2021

MPTP- and MPP(+)-induced effects on body temperature exhibit age- and strain-dependence in mice

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7 January 2021

Genetics of Parkinson's disease

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7 January 2021

Midbrain dopaminergic cell loss in Parkinson's disease: computer visualization

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7 January 2021

The neurotoxin MPTP causes degeneration of specific nucleus A8, A9 and A10 dopaminergic neurons in the mouse

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7 January 2021

The risk of Parkinson's disease with exposure to pesticides, farming, well water, and rural living

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7 January 2021

Differential strain susceptibility following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration acts in an autosomal dominant fashion: quantitative analysis in seven strains of Mus musculus.

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7 January 2021

Differential neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in Swiss-Webster mice from different sources.

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7 January 2021

No mutation of G209A in the alpha-synuclein gene in sporadic Parkinson's disease among Taiwan Chinese

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7 January 2021

Cell-free generation of the notch1 intracellular domain (NICD) and APP-CTfgamma: evidence for distinct intramembranous "gamma-secretase" activities

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https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Glutathione S-transferase Pi is a dopamine-inducible suppressor of dopamine-induced apoptosis in PC12 cells

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https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Evaluation of neurotoxicity of TIQ and MPTP and of parkinsonism-preventing effect of 1-MeTIQ by in vivo measurement of pre-synaptic dopamine transporters and post-synaptic dopamine D(2) receptors in the mouse striatum

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Mapping quantitative trait loci for behavioral traits in the mouse

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https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

From QTL to gene: the harvest begins

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https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Mapping of human potassium channel genes TREK-1 (KCNK2) and TASK (KCNK3) to chromosomes 1q41 and 2p23

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7 January 2021

A novel presenilin 2 gene mutation (D439A) in a patient with early-onset Alzheimer's disease.

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7 January 2021

The molecular bases of Alzheimer's disease and other neurodegenerative disorders

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7 January 2021

Quantitative trait locus mapping of susceptibilities to butylated hydroxytoluene-induced lung tumor promotion and pulmonary inflammation in CXB mice

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7 January 2021

Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration.

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7 January 2021

QTL analysis in a complex autopolyploid: genetic control of sugar content in sugarcane

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7 January 2021

Resistance of golden hamster to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: relationship with low levels of regional monoamine oxidase B.

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7 January 2021

Spontaneous regeneration of nigrostriatal dopaminergic neurons in MPTP-treated C57BL/6 mice

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7 January 2021

Differences in nigral neuron number and sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57/bl and CD-1 mice

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7 January 2021

Inhibition of the tyrosine hydroxylase system by MPTP, 1-methyl-4-phenylpyridinium ion (MPP+) and the structurally related compounds in vitro and in vivo

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7 January 2021

Difference in recovery patterns of striatal dopamine content, tyrosine hydroxylase activity and total biopterin content after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration: a comparison of young and older mice

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7 January 2021

Rate of progression in Parkinson's disease: a 6-[18F]fluoro-L-dopa PET study

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7 January 2021

Genetics of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Four genes for the calpain family locate on four distinct human chromosomes

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https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Etiology and pathogenesis of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Neuron death in the substantia nigra of weaver mouse occurs late in development and is not apoptotic.

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https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Genetic epidemiology of Parkinson's disease

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https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Quantitative trait loci (QTL) analyses and alcohol-related behaviors

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https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

The genetic basis of complex human behaviors

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https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Strain differences in systemic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in mice correlate best with monoamine oxidase activity at the blood-brain barrier

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https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Tyrosine hydroxylase and dopamine transporter expression in residual dopaminergic neurons: potential contributors to spontaneous recovery from experimental Parkinsonism

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7 January 2021

Long-term effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal dopamine content in young and mature mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Mapping QTLs associated with drought resistance in sorghum (Sorghum bicolor L. Moench).

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https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

The α-synuclein gene is not a major risk factor in familial Parkinson disease

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7 January 2021

Pattern of dopaminergic loss in the striatum of humans with MPTP induced parkinsonism

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7 January 2021

Neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and methamphetamine in several strains of mice

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7 January 2021

Alpha-synuclein in Lewy bodies

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7 January 2021

Comparison of intra- and extrasynaptosomal monoamine oxidase-A and -B activities in the striatum and frontal cortex of two mice strains with different sensitivities to the neurotoxic actions of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Etiology of Parkinson's disease

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https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Cell production and cell death in the generation of variation in neuron number

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https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Studies on the effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on central catecholamine neurons in C57BL/6 mice. Comparison with three other strains of mice

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https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900659-9

7 January 2021

Cns distribution of members of the two-pore-domain (KCNK) potassium channel family.

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7 January 2021

Five quantitative trait loci affecting 4-nitroquinoline 1-oxide-induced tongue cancer in the rat.

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7 January 2021

Mild parkinsonism in persons exposed to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

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7 January 2021

The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease.

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7 January 2021

Genetic dissection of complex and quantitative traits: from fantasy to reality via a community effort

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7 January 2021

A quantitative genetic analysis of slow-wave sleep in influenza-infected CXB recombinant inbred mice.

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7 January 2021

Implications of CAD and DNase II in ischemic neuronal necrosis specific for the primate hippocampus

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7 January 2021

Genomic structure and expression of human KCNJ9 (Kir3.3/GIRK3).

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7 January 2021

Genetic and environmental risk factors in Parkinson's disease

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7 January 2021

Natural variation in neuron number in mice is linked to a major quantitative trait locus on Chr 11.

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7 January 2021

Fine mapping and characterization of candidate lung tumor resistance genes for the Par2 locus on mouse chromosome 18.

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7 January 2021

10.1016/S0169-328X(02)00659-9

Identifiers

DOI

1 reference

11 February 2018

1 reference

11 February 2018