(Q48387514)

English

DNA polymerase-beta is expressed early in neurons of Alzheimer's disease brain and is loaded into DNA replication forks in neurons challenged with beta-amyloid.

scientific article published in October 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17065437

DNA polymerase-beta is expressed early in neurons of Alzheimer's disease brain and is loaded into DNA replication forks in neurons challenged with beta-amyloid (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

Alzheimer's disease

0 references

Jeroen Hoozemans

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

Marco Calafiore

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

Maria Angela Sortino

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

Ferdinando Nicoletti

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

author name string

Agata Copani

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

Elise S Van Haastert

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

Robert Veerhuis

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

Annemieke J M Rozemuller

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

Eleonora Aronica

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

language of work or name

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publication date

1 October 2006

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17065437

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

26

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

43

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

10949-10957

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F x DP, in B-amyloid-induced neuronal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitotic signaling by beta-amyloid causes neuronal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential modulation of chemosensitivity to alkylating agents and platinum compounds by DNA repair modulators in human lung cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central role for cdc45 in establishing an initiation complex of DNA replication in Xenopus egg extracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of chromosome replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA replication precedes neuronal cell death in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erratic expression of DNA polymerases by beta-amyloid causes neuronal death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of eukaryotic DNA replication at the initiation step

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle regulation of neuronal apoptosis in development and disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal COX-2 expression and phosphorylation of pRb precede p38 MAPK activation and neurofibrillary changes in AD temporal cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of the 5'-deoxyribose-5-phosphate lyase and DNA synthesis activities of mammalian DNA polymerase beta by apurinic/apyrimidinic endonuclease 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Divide and die: cell cycle events as triggers of nerve cell death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The unfolded protein response is activated in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The origin recognition core complex regulates dendrite and spine development in postmitotic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The emerging role of DNA repair proteins as predictive, prognostic and therapeutic targets in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the JAK-STAT pathway in protection of hydrogen peroxide preconditioning against apoptosis induced by oxidative stress in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinctive, rapid, and easy labeling of diffuse plaques in the Alzheimer brains by a new methenamine silver stain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian DNA polymerase beta can substitute for DNA polymerase I during DNA replication in Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA polymerase beta involvement in DNA endoreduplication in rat giant trophoblast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Global Deterioration Scale for assessment of primary degenerative dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Staging of Alzheimer's disease-related neurofibrillary changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of mammalian DNA polymerase-beta in base-excision repair.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The scaffold/matrix attachment region binding protein hnRNP-U (SAF-A) is directly bound to chromosomal DNA in vivo: a chemical cross-linking study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical localization of redox factor-1 (Ref-1) in Alzheimer's hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17065437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.2793-06.2006

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674652&resulttype=core&format=json

11 May 2020

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