(Q44840270)

English

Modulation of the 5'-deoxyribose-5-phosphate lyase and DNA synthesis activities of mammalian DNA polymerase beta by apurinic/apyrimidinic endonuclease 1.

scientific article published on 11 April 2004

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scholarly article

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Europe PubMed Central

PubMed publication ID

6 December 2017

Modulation of the 5'-deoxyribose-5-phosphate lyase and DNA synthesis activities of mammalian DNA polymerase beta by apurinic/apyrimidinic endonuclease 1. (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

author name string

Donny Wong

1

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

Bruce Demple

2

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

language of work or name

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publication date

11 April 2004

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Europe PubMed Central

PubMed publication ID

6 December 2017

number of pages

8

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Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

6 December 2017

279

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Europe PubMed Central

PubMed publication ID

6 December 2017

24

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

25268-25275

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

DNA damage and repair

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DNA glycosylases in the base excision repair of DNA

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Recent progress in the biology, chemistry and structural biology of DNA glycosylases

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Repair of oxidative damage to DNA: enzymology and biology

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5'-nicked apurinic/apyrimidinic sites are resistant to beta-elimination by beta-polymerase and are persistent in human cultured cells after oxidative stress.

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A method for detecting abasic sites in living cells: age-dependent changes in base excision repair

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Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair

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Structure and function of mammalian DNA ligases

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Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair: the 3' ends justify the means

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The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA.

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An exonucleolytic activity of human apurinic/apyrimidinic endonuclease on 3' mispaired DNA

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Modulation of the 3'-->5'-exonuclease activity of human apurinic endonuclease (Ape1) by its 5'-incised Abasic DNA product

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Going APE over ref-1.

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Human AP-endonuclease 1 and hnRNP-L interact with a nCaRE-like repressor element in the AP-endonuclease 1 promoter

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Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A

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Requirement of mammalian DNA polymerase-beta in base-excision repair.

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The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

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A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity.

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The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity

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Deoxyribose phosphate excision by the N-terminal domain of the polymerase beta: the mechanism revisited

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Covalent trapping of human DNA polymerase beta by the oxidative DNA lesion 2-deoxyribonolactone

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Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps

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Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

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Dynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and product

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AP endonuclease 1 coordinates flap endonuclease 1 and DNA ligase I activity in long patch base excision repair

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Increased activity and fidelity of DNA polymerase beta on single-nucleotide gapped DNA.

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DNA structure and aspartate 276 influence nucleotide binding to human DNA polymerase beta. Implication for the identity of the rate-limiting conformational change

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Incision Activity of Human Apurinic Endonuclease (Ape) at Abasic Site Analogs in DNA

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Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites

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AP lyases and dRPases: commonality of mechanism

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Structure of the DNA repair enzyme endonuclease IV and its DNA complex: double-nucleotide flipping at abasic sites and three-metal-ion catalysis

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DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

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Strategic down-regulation of DNA polymerase beta by antisense RNA sensitizes mammalian cells to specific DNA damaging agents

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Two distinct human DNA diesterases that hydrolyze 3′-blocking deoxyribose fragments from oxidized DNA

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Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis

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XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro

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FEN1 stimulation of DNA polymerase beta mediates an excision step in mammalian long patch base excision repair.

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Identification of 5'-deoxyribose phosphate lyase activity in human DNA polymerase gamma and its role in mitochondrial base excision repair in vitro

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5'-Deoxyribose phosphate lyase activity of human DNA polymerase iota in vitro

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Identifiers

10.1074/JBC.M400804200

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 December 2017

ResearchGate publication ID

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