(Q48389775)

English

Mice deficient in the alpha subunit of G(z) show changes in pre-pulse inhibition, anxiety and responses to 5-HT(1A) receptor stimulation, which are strongly dependent on the genetic background.

scientific article published on 9 August 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17684732

Mice deficient in the alpha subunit of G(z) show changes in pre-pulse inhibition, anxiety and responses to 5-HT(1A) receptor stimulation, which are strongly dependent on the genetic background. (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17684732

author name string

Maarten van den Buuse

1

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17684732

Sally Martin

2

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17684732

Joan Holgate

3

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17684732

Klaus Matthaei

4

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17684732

Ian Hendry

5

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17684732

publication date

9 August 2007

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17684732

Psychopharmacology

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17684732

195

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17684732

2

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17684732

273-283

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17684732

https://scigraph.springernature.com/pub.10.1007/s00213-007-0888-7

0 references

The 5-HT(1A) receptor knockout mouse and anxiety

1 reference

https://api.crossref.org/works/10.1007%2FS00213-007-0888-7

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Different behavioural profiles of the R(+)- and S(-)-enantiomers of 8-hydroxy-2-(di-n-propylamino) tetralin in the murine elevated plus-maze.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

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Susceptibility genes for schizophrenia: characterisation of mutant mouse models at the level of phenotypic behaviour.

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The 5-HT1A receptor in schizophrenia: a promising target for novel atypical neuroleptics?

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https://pubmed.ncbi.nlm.nih.gov/17684732

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Molecular, pharmacological and functional diversity of 5-HT receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

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Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies

1 reference

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Inbred strain differences in prepulse inhibition of the mouse startle response

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

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Gz, a guanine nucleotide-binding protein with unique biochemical properties.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

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The fallacy of behavioral phenotyping without standardisation

1 reference

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Variability in the benzodiazepine response of serotonin 5-HT1A receptor null mice displaying anxiety-like phenotype: evidence for genetic modifiers in the 5-HT-mediated regulation of GABA(A) receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

12 December 2020

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Stimulation of 5-HT1A receptors by systemic or medial septum injection induces anxiogenic-like effects and facilitates acquisition of a spatial discrimination task in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

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Association of the functional -1019C/G 5-HT1A polymorphism with prefrontal cortex and amygdala activation measured with 3 T fMRI in panic disorder.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

12 December 2020

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Focus on The 5-HT1A receptor: emerging role of a gene regulatory variant in psychopathology and pharmacogenetics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

12 December 2020

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The recombinant 5-HT1A receptor: G protein coupling and signalling pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

12 December 2020

based on heuristic

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5-HT1A and 5-HT2A receptor mRNAs and binding site densities are differentially altered in schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

12 December 2020

based on heuristic

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The anxiety-like phenotype of 5-HT receptor null mice is associated with genetic background-specific perturbations in the prefrontal cortex GABA-glutamate system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

12 December 2020

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Reduced effects of amphetamine on prepulse inhibition of startle in gastrin-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

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Loss of signaling through the G protein, Gz, results in abnormal platelet activation and altered responses to psychoactive drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

12 December 2020

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Selective breeding, congenic strains, and other classical genetic approaches to the analysis of alcohol-related polygenic pleiotropisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

12 December 2020

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Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

12 December 2020

based on heuristic

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Gz proteins are functionally coupled to dopamine D2-like receptors in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

12 December 2020

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Human 5-HT1A receptor C(-1019)G polymorphism and psychopathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

12 December 2020

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Genetics of mouse behavior: interactions with laboratory environment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

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Differences in fear motivated behaviors among inbred mouse strains.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

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Animal models of 'anxiety': where next?

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https://pubmed.ncbi.nlm.nih.gov/17684732

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5-HT1A receptors, gene repression, and depression: guilt by association

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

12 December 2020

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Knockout mice reveal opposite roles for serotonin 1A and 1B receptors in prepulse inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

12 December 2020

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Effect of 5-HT1A receptor gene polymorphism on negative and depressive symptom response to antipsychotic treatment of drug-naive psychotic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

12 December 2020

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Use of the elevated plus maze in the search for novel anxiolytic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

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Enhanced serotonin response in the hippocampus of Galphaz protein knock-out mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

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Regional differences in the coupling of 5-hydroxytryptamine-1A receptors to G proteins in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

12 December 2020

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Effects of strain and serotonergic agents on prepulse inhibition and habituation in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

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Oestrogen modulation of the effect of 8-OH-DPAT on prepulse inhibition: effects of aromatase deficiency and castration in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

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Mouse genetic models for prepulse inhibition: an early review

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

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Enhanced effect of dopaminergic stimulation on prepulse inhibition in mice deficient in the alpha subunit of G(z).

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

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8-OH-DPAT-induced effects on prepulse inhibition: pre- vs. post-synaptic 5-HT1A receptor activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

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Hypertolerance to morphine in G(z alpha)-deficient mice

1 reference

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5-HT1A receptor binding sites in post-mortem brain samples from depressed suicides and controls

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Gene targeting: technical confounds and potential solutions in behavioral brain research

1 reference

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Strain-dependent expression of signaling proteins in the mouse hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17684732

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Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests

1 reference

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Identifiers

10.1007/S00213-007-0888-7

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17684732

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17684732

ResearchGate publication ID

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